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OptimizeRx Corporation (OPRX)
NASDAQ:OPRX
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OptimizeRx (OPRX) AI Stock Analysis

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OPRX

OptimizeRx

(NASDAQ:OPRX)

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Neutral 58 (OpenAI - 4o)
Rating:58Neutral
Price Target:
$16.50
▲(5.43% Upside)
OptimizeRx's overall stock score reflects a mix of strong revenue growth and operational improvements, as highlighted in the earnings call, but is weighed down by technical indicators showing bearish momentum and a challenging valuation due to negative profitability. The company's financial performance shows potential, but profitability and technical trends need improvement for a higher score.
Positive Factors
Revenue Growth
The 22% YoY revenue growth in Q3 indicates strong market demand and successful product adoption, supporting long-term business expansion.
Gross Margin Expansion
Improved gross margins reflect efficient cost management and economies of scale, enhancing profitability potential over time.
Debt Reduction
Accelerated debt reduction strengthens the balance sheet, reducing financial risk and improving long-term financial flexibility.
Negative Factors
Profitability Challenges
Ongoing profitability issues, with negative net income and EBIT margins, could hinder long-term financial sustainability and growth.
Operating Expenses
Rising operating expenses from variable compensation can strain margins, impacting operational efficiency and financial performance.
Flat Revenue Growth Expectations
Flat revenue growth expectations for Q4 may indicate market saturation or competitive pressures, affecting future growth prospects.

OptimizeRx (OPRX) vs. SPDR S&P 500 ETF (SPY)

OptimizeRx Business Overview & Revenue Model

Company DescriptionOptimizeRx (OPRX) is a healthcare technology company that operates in the digital health sector, focusing on improving patient outcomes through its innovative platform. The company provides a suite of solutions designed to enhance patient access to medications and streamline communication between healthcare providers, patients, and pharmaceutical companies. OptimizeRx's core products include electronic health record (EHR) integrations that facilitate the delivery of patient savings programs and medication information directly within the clinical workflow, thereby enhancing the prescribing process and adherence to treatment regimens.
How the Company Makes MoneyOptimizeRx generates revenue primarily through its digital health platform, which offers services to pharmaceutical companies, healthcare providers, and payers. The company earns money by charging pharmaceutical manufacturers for access to its platform, where they can promote their patient support programs and discounts directly to healthcare providers. Additionally, OptimizeRx monetizes its EHR integrations by providing value-added services that enhance the functionality of electronic health records, driving user engagement and adoption. Partnerships with leading EHR vendors and collaborations with various healthcare stakeholders further contribute to its revenue streams by expanding its market reach and enhancing its service offerings.

OptimizeRx Earnings Call Summary

Earnings Call Date:Nov 06, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Feb 19, 2026
Earnings Call Sentiment Positive
The earnings call reflected strong financial performance in Q3 with significant revenue and EBITDA growth, increased guidance for the current and following fiscal year, and strategic debt reduction. Despite these achievements, expectations for Q4 are conservative, and operating expenses have increased due to higher variable compensation. Overall, the sentiment is positive, with a focus on continued growth and operational excellence.
Q3-2025 Updates
Positive Updates
Strong Third Quarter Performance
Q3 revenues increased 22% year-over-year to $26.1 million, with adjusted EBITDA at $5.1 million, an improvement of over $2 million from the same period last year.
Increased Guidance for 2025 and 2026
Guidance updated to $105 million - $109 million in revenue for 2025, with adjusted EBITDA between $16 million and $19 million. Initial guidance for 2026 projects revenue of $118 million to $124 million and adjusted EBITDA of $19 million to $22 million.
Operational Excellence and Debt Reduction
Paid down an additional $2 million on the term loan principal, with a total principal paydown for the year at $7.5 million. The company intends to continue debt reduction at an accelerated rate.
Gross Margin Expansion
Gross margin increased from 63.1% in Q3 2024 to 67.2% in Q3 2025, driven by favorable product mix and economies of scale.
Positive RFP Trends
Favorable RFP trends for 2026 with increased interest in both HCP and DTC channels, suggesting continued growth potential.
Negative Updates
Flat Revenue Growth Expectations for Q4
Implied guidance for Q4 suggests a slight year-over-year decline at the top end of the range, with the focus on full-year performance rather than quarterly results.
Variable Compensation Impact on Operating Expenses
Cash operating expenses increased due to higher bonus and commission payouts, reflecting strong performance but impacting overall operating leverage.
Company Guidance
During OptimizeRx's third-quarter fiscal year 2025 earnings call, the company reported a 22% year-over-year increase in Q3 revenues, reaching $26.1 million, and a significant improvement in adjusted EBITDA, which rose to $5.1 million, an increase of over $2 million from the previous year. The company announced upward revisions to its full-year guidance, now expecting 2025 revenues between $105 million and $109 million and adjusted EBITDA between $16 million and $19 million. Additionally, OptimizeRx introduced initial guidance for fiscal year 2026, projecting revenues between $118 million and $124 million, with adjusted EBITDA anticipated to be between $19 million and $22 million. The company highlighted a successful focus on operational excellence, evidenced by strong contracted revenue growth and improvements in average revenue per customer, with the top 5 customers generating over $11 million each. OptimizeRx also emphasized its strategic efforts in enhancing gross margins, primarily driven by favorable product mix and economies of scale, and announced plans to continue accelerating debt repayment, reducing its term loan principal by an additional $2 million beyond the scheduled payments.

OptimizeRx Financial Statement Overview

Summary
OptimizeRx shows positive revenue and cash flow growth, but faces profitability challenges with negative net profit margins. The strong equity position and low leverage provide a stable financial foundation.
Income Statement
55
Neutral
OptimizeRx shows a positive revenue growth trend, with a TTM revenue increase of 2.43% compared to the previous year. However, the company is facing profitability challenges, as indicated by negative EBIT and net income margins. The gross profit margin remains strong at 62.97%, but the net profit margin is negative at -16.33%, reflecting ongoing operational inefficiencies.
Balance Sheet
65
Positive
The balance sheet reflects a solid equity position with a debt-to-equity ratio of 0.28, indicating low leverage. The equity ratio is robust at 69.28%, showing a strong capital structure. However, the company has experienced a decline in total assets, which may impact future growth potential.
Cash Flow
70
Positive
OptimizeRx demonstrates a positive trend in cash flow, with a significant increase in free cash flow by 32.12% in the TTM period. The operating cash flow to net income ratio is favorable, indicating efficient cash generation relative to net losses. However, the company needs to maintain this momentum to ensure long-term financial stability.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue104.75M92.13M71.52M62.45M61.29M43.31M
Gross Profit67.45M59.38M42.90M38.97M35.64M24.11M
EBITDA1.04M-8.90M-21.31M-9.42M2.33M646.89K
Net Income-9.87M-20.11M-17.57M-11.44M378.08K-2.21M
Balance Sheet
Total Assets169.26M171.17M183.37M134.65M140.99M60.33M
Cash, Cash Equivalents and Short-Term Investments16.59M13.38M13.85M74.14M84.68M10.52M
Total Debt3.85M33.19M36.82M234.43K327.71K448.75K
Total Liabilities49.98M54.17M56.82M8.54M9.61M10.35M
Stockholders Equity119.28M117.00M126.55M126.11M131.38M49.97M
Cash Flow
Free Cash Flow10.16M4.78M-8.11M10.41M240.04K-6.44M
Operating Cash Flow10.41M4.89M-7.24M10.65M726.04K-6.31M
Investing Cash Flow-340.00K-450.00K-25.34M-58.18M-486.00K-124.72K
Financing Cash Flow-8.45M-4.91M28.22M-18.95M73.92M-1.90M

OptimizeRx Technical Analysis

Technical Analysis Sentiment
Negative
Last Price15.65
Price Trends
50DMA
18.87
Negative
100DMA
16.59
Negative
200DMA
12.63
Positive
Market Momentum
MACD
-0.15
Positive
RSI
34.65
Neutral
STOCH
17.61
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For OPRX, the sentiment is Negative. The current price of 15.65 is below the 20-day moving average (MA) of 19.66, below the 50-day MA of 18.87, and above the 200-day MA of 12.63, indicating a neutral trend. The MACD of -0.15 indicates Positive momentum. The RSI at 34.65 is Neutral, neither overbought nor oversold. The STOCH value of 17.61 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for OPRX.

OptimizeRx Risk Analysis

OptimizeRx disclosed 33 risk factors in its most recent earnings report. OptimizeRx reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

OptimizeRx Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
72
Outperform
$283.64M17.2110.88%9.04%1.47%11.33%
69
Neutral
$1.60B83.681.62%10.67%
67
Neutral
$734.21M36.525.87%0.48%3.68%5.62%
58
Neutral
$351.62M0.03%24.19%
57
Neutral
$288.37M-22.761.68%3.75%
57
Neutral
$316.27M-4.26-86.09%13.66%-2.65%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
OPRX
OptimizeRx
15.65
9.59
158.25%
TBRG
TruBridge
19.42
5.11
35.71%
HSTM
HealthStream
24.65
-7.79
-24.01%
OMCL
Omnicell
35.68
-13.18
-26.98%
SPOK
Spok Holdings
13.44
-2.36
-14.94%
SOPH
SOPHiA GENETICS
4.37
0.58
15.30%

OptimizeRx Corporate Events

OptimizeRx Earnings Call: Strong Q3 and Upbeat Outlook
Nov 8, 2025

The recent earnings call for OptimizeRx Corporation showcased a strong financial performance in the third quarter, marked by significant revenue and EBITDA growth. The company has raised its guidance for the current and upcoming fiscal years, while also making strategic moves to reduce debt. Despite these achievements, the company remains conservative in its expectations for the fourth quarter, citing increased operating expenses due to higher variable compensation. Overall, the sentiment of the call was positive, with a clear focus on sustained growth and operational excellence.

OptimizeRx Reports Strong Q3 Growth and Raises Guidance
Nov 7, 2025

OptimizeRx Corporation, headquartered in Waltham, Massachusetts, is a prominent healthcare technology company that specializes in connecting life science brands with patients and healthcare providers through innovative AI-driven tools. The company’s platform facilitates timely and relevant engagement, enhancing healthcare outcomes.

Business Operations and StrategyExecutive/Board Changes
OptimizeRx Announces Leadership Changes for Strategic Growth
Positive
Aug 19, 2025

On August 19, 2025, OptimizeRx Corporation announced leadership changes aimed at accelerating its strategic growth and achieving the Rule of 40 strategy, which balances sustained growth with increased profitability. Brendan Merrell was appointed as the Chief Operating Officer, while Edward Stelmakh transitioned to the role of Chief Financial & Strategic Officer to lead corporate strategy and financial operations. These changes reflect the company’s commitment to aligning talent and structure with its long-term strategic objectives under CEO Steve Silvestro’s management. The leadership advancements, including the promotion of Andy D’Silva to Chief Business Officer, are designed to enhance the company’s focus on profitable growth and shareholder value creation.

The most recent analyst rating on (OPRX) stock is a Hold with a $18.50 price target. To see the full list of analyst forecasts on OptimizeRx stock, see the OPRX Stock Forecast page.

OptimizeRx Earnings Call: Strong Growth and Positive Outlook
Aug 13, 2025

The recent earnings call for OptimizeRx Corporation painted a predominantly positive picture, marked by significant revenue growth, improved financial health, and increased guidance for the coming year. While the company expressed confidence in its strategic positioning and operational excellence, there were some concerns about the sustainability of revenue growth due to reliance on managed services and uncertainties in future revenue predictions. Nonetheless, the positive elements of the call notably outweighed the concerns, leaving investors with an optimistic outlook.

OptimizeRx Reports Strong Q2 2025 Financial Growth
Aug 8, 2025

OptimizeRx Corporation, a healthcare technology company based in Waltham, Massachusetts, specializes in connecting life sciences brands with healthcare providers and patients through AI-driven tools. The company recently reported a significant financial improvement for the second quarter of 2025, showcasing a 55% increase in revenue to $29.2 million and a 59% rise in gross profit to $18.6 million year-over-year.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 08, 2025