Mrna-1345, Mrna-1365
Respiratory Syncytial Virus (Rsv), Human Metapneuomovirus (Hmpv)
Phase I
Not Yet Recruiting
A Study to Investigate Safety, Reactogenicity, and Immunogenicity of mRNA-1365 (Profile 2) in Older Healthy Adults
Aug 10, 2026
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Intismeran, Pembrolizumab Coformulated With Berahyaluronidase Alfa, Mrna-4157, V940
Non-small Cell Lung Cancer
Phase III
Recruiting
A Clinical Trial of Adjuvant Intismeran (V940) With or Without Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) in High-Risk Stage I Non-Small Cell Lung Cancer (V940-014)
Apr 01, 2026
Mrna-1273, Mrna-1283, Mrna-1283.222, Mrna-1273.222, Mrna-1283.815, Mrna-1273.815, Mrna-1283.211, Mrna-1283.529, Mrna-1283.251 Variant-Containing Formulation
Sars-Cov-2
Phase IV
Recruiting
A Study to Evaluate the Efficacy and Safety of mRNA-1283 and mRNA-1273 in Participants 50 to 64 Years of Age Without High-Risk Conditions for Severe Coronavirus Disease 2019 (COVID-19)
Nov 25, 2025
Carboplatin, Pembrolizumab, Paclitaxel, Nab-Paclitaxel, Intismeran Autogene, V940, Keytruda, Mrna-4157
Squamous Non-Small Cell Lung Cancer
Phase II
Recruiting
A Study of Intismeran Autogene (V940)/Placebo + Pembrolizumab and Chemotherapy in Metastatic Squamous Non-Small Cell Lung Cancer (V940-013)
Oct 24, 2025
FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Moderna (MRNA) have in its pipeline
MRNA is currently developing the following drugs: Mrna-1345, Mrna-1365, Mrna-1469, Mrna-1982. These drug candidates are in various stages of clinical development as the company works toward FDA approval.