EarningsQ4 2025 Earnings Report

Ionis Pharmaceuticals (IONS) Q4 2025 Earnings Report

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MX:IONS Q4 2025 EPS Results

Actual EPS-$25.39

Consensus EPS-$23.75

Beat/MissMissed by -$1.64

One Year Ago EPS-$11.88

Actual Revenue$3.65B

Expected Revenue$2.84B

Beat/MissBeat by +$815.99M

YoY Revenue Growth-10.57%

QuarterQ4 2025

Date02/25/2026

TimeBefore Open

Conference CallWednesday, February 25, 2026

MX:IONS Upcoming Earnings

Ionis Pharmaceuticals's next earnings date is estimated for November 4, 2026, based on past reporting schedules.

MX:IONS Q4 2025 Earnings Call

0:00 / 0:00

No earnings call summary is available for this earnings event.

Report Date	Fiscal Quarter	Forecast / EPS	Last Year's EPS	EPS YoY Change
Nov 04, 2026	2026 (Q3)	-21.79 / -	-14.404	―
Jul 29, 2026	2026 (Q2)	-19.61 / -12.42	12.603	-198.57% (-25.03)
Apr 29, 2026	2026 (Q1)	-15.79 / -10.08	-16.744	39.78% (+6.66)
Feb 25, 2026	2025 (Q4)	-23.75 / -25.39	-11.883	-113.64% (-13.50)
Oct 29, 2025	2025 (Q3)	-21.93 / -14.40	-17.104	15.79% (+2.70)
Jul 30, 2025	2025 (Q2)	-1.64 / 12.60	-8.102	255.56% (+20.71)
Apr 30, 2025	2025 (Q1)	-19.77 / -16.74	-17.645	5.10% (+0.90)
Feb 19, 2025	2024 (Q4)	-20.24 / -11.88	-1.08	-1000.00% (-10.80)
Nov 06, 2024	2024 (Q3)	-20.47 / -17.10	-18.545	7.77% (+1.44)
Aug 01, 2024	2024 (Q2)	-16.87 / -8.10	-10.803	25.00% (+2.70)

The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.

Beat

Missed