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Charles River Labs (CRL) AI Stock Analysis

MX:CRL

Charles River Labs

(BMV:CRL)

Rating:―N/A
Action:N/A
Date:―

No summary available

Positive Factors
DSA DemandStronger bookings, backlog, and book-to-bill indicate improving demand for Charles River’s discovery and safety services. These indicators support revenue visibility over the next several quarters and reinforce the company’s role in customers’ preclinical development programs.
Negative Factors
Profitability DeclineThe shift from double-digit net margins in earlier years to losses materially weakens current earnings power. Sustained profitability recovery will be necessary to restore financial resilience, support reinvestment, and demonstrate that recent margin actions are durable.

Charles River Labs (CRL) vs. SPDR S&P 500 ETF (SPY)

-25%0%25%50%75%100%125%MX:CRL+107.67%SPY+11.79%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
Market Cap
MXN 17.31B
Dividend Yield
―
Average Volume (3M)
20
Price to Earnings (P/E)
-74.3
Beta (1Y)
-0.21
Revenue Growth
-9.60%
EPS Growth
-209.99%
Country
Mexico
Employees
19,000
Sector
Healthcare
Sector Strength
51
Industry
Medical - Diagnostics & Research

Charles River Labs Business Overview & Revenue Model

Company Description

Charles River Laboratories International, Inc. operates as a contract research organization (CRO), providing essential preclinical services to the pharmaceutical and biotechnology industries. Its core business revolves around assisting clients with d...

Charles River Labs Earnings Call Summary

Earnings Call Date:Aug 04, 2026(Q2-2026)|% Change Since:65.65%|Next Earnings Date:Nov 03, 2026
Earnings Call SentimentPositive

The call highlighted clear operational progress: better-than-expected Q2 results, sequential margin improvement (420 bps), stronger DSA demand signals with bookings/backlog gains and raised full-year guidance (organic revenue guidance improved by ~150 bps and EPS guidance raised). Strategic actions (divestitures, NHP supply integration, partnerships, AI/digital investments and lab expansions) are positioned to drive further margin and growth upside. However, notable near-term challenges remain: RMS softness driven by North American academic/government funding constraints, Q2 free cash flow decline, higher corporate costs and an elevated tax rate headwind, plus timing risk with material NHP sourcing benefits largely back-loaded into Q4 and pricing improvements not yet realized. On balance, positives (outperformance, raised guidance, bookings/backlog strength, margin momentum and strategic partnerships) outweigh the lowlights, though some operational and timing risks persist.

Positive Updates

Beat Quarterly Outlook and Raised Full-Year Guidance
Q2 results exceeded prior outlook for revenue and non-GAAP EPS; company raised full-year organic revenue guidance to flat to +1% (150 bps improvement) and increased non-GAAP EPS guidance to $11.15–$11.45 (8%–11% YoY growth).

Negative Updates

RMS Segment Underperformance
RMS organic revenue declined -1.4% in Q2 driven by lower volumes for small research models and research model services (GEMS) in North America; company still expects low-to-mid single-digit organic RMS decline for the year.

Company Guidance

The company raised its full-year 2026 outlook, now expecting reported revenue to decline 2.5%–3.5% while organic revenue should be flat to up 1% (a 150‑bp improvement versus prior guidance); by segment management guides DSA to low single‑digit organic growth, Manufacturing to low‑ to mid‑single‑digit organic growth, and RMS to a low‑ to mid‑single‑digit organic decline. Full‑year non‑GAAP operating margin is forecast to expand ~120–150 bps, with a clear line of sight to at least a 500‑bp improvement in H2 versus H1 (about half of the H2 improvement from completed portfolio actions and lower NHP sourcing costs, ~150 bps from lower corporate costs, remainder from operational contributions), and non‑GAAP EPS is raised to $11.15–$11.45 (≈8%–11% YoY). Additional metrics: Q3 reported revenue is expected to decline ~4%–6% while Q3 organic revenue should grow ~1%–3%, Q3 non‑GAAP EPS is guided to $2.90–$3.00 (≈20% YoY) with roughly +200 bps sequential margin improvement, full‑year non‑GAAP tax rate 23%–24% (≈+100 bps; ~$0.20 EPS headwind), net interest expense $103M–$108M, free cash flow raised to $400M–$420M, average diluted shares ~48.5M, net leverage ~2.5x, and $300M of share repurchases year‑to‑date (including $100M in Q2) under a $1B authorization.

Charles River Labs Risk Analysis

Charles River Labs disclosed 41 risk factors in its most recent earnings report. Charles River Labs reported the most risks in the "Legal & Regulatory" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Legal & Regulatory - Litigation, compliance, new legislation, and taxation risks

Latest Risks Added

1 New Risk
1.We have in the past experienced and in the future could experience unauthorized access into our information systems.Q1, 2026

Charles River Labs Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

MX:CRL against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
MEDPMEDP84Outperform$18.24B35.5199.76%―20.35%25.24%
TMOTMO77Outperform$257.71B36.7013.31%0.26%8.27%9.59%
LHLH75Outperform$29.31B29.4511.54%0.80%6.02%19.63%
IQVIQV74Outperform$44.06B32.1321.82%―8.88%13.11%
ICLRICLR69Neutral$16.31B36.134.85%―0.67%43.70%
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%

* Healthcare Sector Average

Performance Comparison

-50%0%50%100%MX:CRLICLRLHTMOIQVMEDPDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26
MX:CRL and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
MX:CRLCharles River Laboratories Intl6559.903401.14107.67%
ICLRIcon Plc211.3642.5725.22%
LHLabcorp Holdings Inc.361.39106.1341.58%
TMOThermo Fisher Scientific697.00134.1023.82%
IQVIQVIA Holdings267.3353.4524.99%
MEDPMedpace Holdings Inc652.0157.999.76%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
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SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.