Bms-986446
Healthy Participants, Alzheimer's Disease
Phase I
Not Yet Recruiting
A Study to Evaluate the Drug Levels, Absolute Bioavailability, Safety, Tolerability, and Immunogenicity of Single-Dose of BMS-986446 in Healthy Adults After Single-dose Administration, and Participants With Early Alzheimer's Disease After Multiple Dose Administration
Aug 19, 2026
Carboplatin, Cisplatin, Pemetrexed, Osimertinib, Iza-Bren, Bms-986507
Non-small Cell Lung Cancer
Phase III
Not Yet Recruiting
Study of Izalontamab Brengitecan (BMS-986507) in Combination With Osimertinib Versus Osimertinib Monotherapy or Osimertinib in Combination With Platinum-based Chemotherapy for EGFRmt Non-small Cell Lung Cancer (IZABRIGHT-Lung02)
Jun 26, 2026
Pumitamig, Pm8002, Imzokitug, Bnt327, Bms-986340
Metastatic Non-Small Cell Lung Cancer (Nsclc), Locally Advanced Non-Small Cell Lung Cancer (Nsclc)
Phase II
Recruiting
A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Jun 26, 2026
Rosuvastatin, Dabigatran Etexilate, Famotidine, Bms-986533
Healthy Volunteers
Phase I
Recruiting
Single and Multiple Dose Study to Evaluate Safety and Pharmacokinetics of BMS-986533 in Healthy Participants and Assessments of Food and pH Effects on Relative Bioavailability, and Drug-Drug Interaction Potential in Healthy Participants
Jun 01, 2026
FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Bristol-Myers Squibb (BMY) have in its pipeline
BMY is currently developing the following drugs: Deucravacitinib, Bms-986446, Navlimetostat, [14C]Navlimetostat, Bms-986504. These drug candidates are in various stages of clinical development as the company works toward FDA approval.