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MetaVia (MTVA) AI Stock Analysis

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MTVA

MetaVia

(NASDAQ:MTVA)

Select Model
Rating:45Neutral
Price Target:$1.50â–²(4.17% Upside)
Action:reiterated
Date:11/07/26

The score is primarily held down by weak financial performance (no revenue, continued losses, and material cash burn with potential dilution risk). Technicals are also modestly negative with the price below key longer-term moving averages and a negative MACD, while valuation metrics offer limited support due to a negative P/E and no dividend yield.

Positive Factors
Clinical EfficacyThe interim Phase 1 results provide encouraging human evidence for DA-1726 across both liver-fat reduction and weight loss. If reproduced in larger and longer studies, this combination could support differentiation in obesity and broader cardiometabolic treatment markets.
Negative Factors
Pre-Revenue ModelMetaVia has not yet demonstrated commercial revenue generation, so its current operating model depends on advancing pipeline assets rather than established product sales. Persistent losses and negative gross profit leave future profitability contingent on successful development, approval, and eventual commercialization.

MetaVia (MTVA) vs. SPDR S&P 500 ETF (SPY)

-100%-75%-50%-25%0%25%50%MTVA-81.27%SPY+14.28%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
$9.49M
Dividend Yield
―
Average Volume (3M)
114.12K
Price to Earnings (P/E)
-0.4
Beta (1Y)
1.41
Revenue Growth
―
EPS Growth
79.26%
Country
US
Employees
8
Sector
Healthcare
Sector Strength
51
Industry
Biotechnology

MetaVia Business Overview & Revenue Model

Company Description

Headquartered in Cambridge, Massachusetts, MetaVia Inc. operates as a clinical-stage biotechnology company with a core focus on discovering and commercializing novel pharmaceutical solutions for cardiometabolic disorders. Its leading investigational...

MetaVia Financial Statement Overview

Summary

Financials are dominated by early-stage biotech risk: zero revenue, recurring net losses (TTM net income -$14.4M), and substantial ongoing cash burn (TTM operating/FCF about -$15.8M). The key offset is low leverage (minimal debt) and positive equity, but equity has trended down meaningfully, increasing future funding/dilution risk.

Income Statement

12Very Negative

Balance Sheet

58Neutral

Cash Flow

18Very Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Mar 2022
Income Statement
Total Revenue000000
Gross Profit-10.00K-19.00K-24.00K-7,000-28.00K-72.00K
EBITDA-14.50M-12.95M-27.57M-12.46M-11.76M-15.24M
Net Income-14.45M-12.97M-27.59M-12.47M-13.97M-15.28M
Balance Sheet
Total Assets13.27M11.12M16.26M22.78M33.53M16.80M
Cash, Cash Equivalents and Short-Term Investments12.63M10.28M16.02M22.43M33.36M16.39M
Total Debt177.00K210.00K136.00K203.00K071.00K
Total Liabilities6.45M5.79M8.33M6.10M11.78M2.20M
Stockholders Equity6.82M5.33M7.93M16.68M21.75M14.60M
Cash Flow
Free Cash Flow-15.84M-15.70M-24.72M-10.85M-11.71M-15.14M
Operating Cash Flow-15.84M-15.70M-24.71M-10.80M-11.71M-15.13M
Investing Cash Flow0-2,000-8,000-50.00K8,000-586.00K
Financing Cash Flow10.88M9.96M18.30M-80.00K28.68M22.03M

MetaVia Technical Analysis

Technical Analysis SentimentPositive
Last Price1.44

Price Trends

50DMA1.48Negative
100DMA1.52Negative
200DMA1.61Negative

Market Momentum

MACD-0.01Negative
RSI52.98Neutral
STOCH65.57Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MTVA, the sentiment is Positive. The current price of 1.44 is above the 20-day moving average (MA) of 1.30, below the 50-day MA of 1.48, and below the 200-day MA of 1.61, indicating a neutral trend. The MACD of -0.01 indicates Negative momentum. The RSI at 52.98 is Neutral, neither overbought nor oversold. The STOCH value of 65.57 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for MTVA.

MetaVia Risk Analysis

MetaVia disclosed 66 risk factors in its most recent earnings report. MetaVia reported the most risks in the "Tech & Innovation" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Tech & Innovation - Risks related to the company’s reliance on technology and ability to make innovative products

Latest Risks Added

2 New Risks
1.Adverse global economic conditions could have a negative effect on our business, results of operations and financial condition and liquidity.Q4, 2023
2.Conditions in the banking system and financial markets, including the failure of banks and financial institutions, could have an adverse effect on our operations and financial results.Q4, 2023

MetaVia Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

MTVA against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
RLYBRLYB54Neutral$84.85M3.4336.35%86.32%-35.61%―
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
MTVAMTVA45Neutral$9.82M-0.35-209.67%――79.26%
CTXRCTXR43Neutral$13.53M-0.23-67.15%――57.48%
PMNPMN40Underperform$35.69M-0.22-143.09%――-169.38%

* Healthcare Sector Average

Performance Comparison

0%100%200%MTVAPMNCTXRRLYBKAPADec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
MTVA and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
MTVAMetavia Inc.1.44-5.82-80.17%
PMNProMIS Neurosciences Inc.3.76-6.00-61.46%
CTXRCitius Pharma0.48-0.53-52.48%
RLYBRallybio Corporation15.8010.55201.07%
KAPAKairos Pharma, Ltd.0.51-5.03-90.81%

MetaVia Corporate Events

Product-Related Announcements

MetaVia Reports Positive Interim Results for DA-1726 Trial

Positive
Nov 5, 2026

On November 5, 2026, MetaVia reported positive interim results from Part 3B of DA-1726’s Phase 1 trial in otherwise healthy adults with obesity. The results, presented on November 4, showed statistically significant 68% placebo-adjusted liver-fat red...

Business Operations and StrategyProduct-Related Announcements

MetaVia highlights DA-1726 obesity trial data progress

Positive
Oct 28, 2026

On October 28, 2026, MetaVia announced that Phase 1 clinical trial data for its investigational dual GLP-1 and glucagon receptor agonist DA-1726 will be presented in an oral session at the Precision Liver Symposium 2026 on November 4 in Denver. The p...

Business Operations and StrategyExecutive/Board Changes

MetaVia Appoints New Chief Medical Officer for Pipeline

Positive
Oct 13, 2026

On October 13, 2026, MetaVia announced that Sarah Kaplan Browne, M.D., had been appointed Chief Medical Officer, effective October 12, 2026, bringing more than two decades of experience in clinical development, regulatory science and clinical medicin...

Business Operations and StrategyProduct-Related Announcements

MetaVia Highlights DA-1726 Preclinical Data for Obesity Program

Positive
Sep 9, 2026

On September 9, 2026, MetaVia reported preclinical tissue distribution data for its obesity drug candidate DA-1726, showing that DA-1726-derived radioactivity is slowly absorbed, broadly distributed, and most concentrated in adipose tissue, with mini...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Nov 07, 2026