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Heartseed, Inc. (219A) AI Stock Analysis
Heartseed, Inc.
(TSE/TYO:219A)
The overall score of 80 is heavily driven by an exceptional financial turnaround, characterized by robust free cash flow generation and a pristine, debt-free balance sheet. Strong technical momentum further supports the stock, with shares trending well above all major moving averages. These significant strengths are only partially offset by a weak trailing valuation profile, specifically a negative P/E ratio and no dividend.
Heartseed, Inc. (219A) vs. iShares MSCI Japan ETF (EWJ)
- Market Cap
- JPY 68.92B
- Dividend Yield
- ―
- Average Volume (3M)
- 477.52K
- Price to Earnings (P/E)
- -102.7
- Beta (1Y)
- 0.71
- Revenue Growth
- ―
- EPS Growth
- ―
- Country
- Japan
- Employees
- 43
- Sector
- General
- Sector Strength
- 55
- Industry
- Biotechnology
Heartseed, Inc. Business Overview & Revenue Model
Company Description
Heartseed Inc. is a Japan-based company engaged in research and development of regenerative medicine products. The company has established cardiac regenerative medicine, a therapy in which microtissue derived from iPS cells is transplanted into the h...
Heartseed, Inc. Financial Statement Overview
Summary
Exceptional financial health driven by a successful pivot to profitability with strong operating margins. The company boasts a pristine, virtually debt-free balance sheet and robust free cash flow conversion exceeding 1 billion.
Income Statement
88Very PositiveBalance Sheet
95Very PositiveCash Flow
90Very Positive| Breakdown | TTM | Oct 2025 | Oct 2024 | Oct 2023 | Oct 2022 |
|---|---|---|---|---|---|
Income Statement | |||||
| Total Revenue | 3.03B | 3.03B | 873.61M | 344.73M | 499.06M |
| Gross Profit | 3.03B | 3.03B | 0 | 0 | 0 |
| EBITDA | 778.63M | 278.71M | -996.98M | -1.45B | -1.46B |
| Net Income | 592.50M | 163.38M | -812.73M | -1.47B | -1.41B |
Balance Sheet | |||||
| Total Assets | 8.14B | 8.14B | 7.07B | 5.72B | 4.94B |
| Cash, Cash Equivalents and Short-Term Investments | 7.34B | 7.34B | 5.30B | 4.59B | 3.99B |
| Total Debt | 890.00K | 890.00K | 5.39M | 11.58M | 30.98M |
| Total Liabilities | 571.35M | 571.35M | 444.34M | 450.19M | 208.45M |
| Stockholders Equity | 7.57B | 7.57B | 6.62B | 5.27B | 4.73B |
Cash Flow | |||||
| Free Cash Flow | 1.05B | 1.05B | -1.36B | -1.13B | -1.92B |
| Operating Cash Flow | 1.08B | 1.08B | -1.34B | -797.93M | -1.92B |
| Investing Cash Flow | 72.64M | 72.64M | -67.13M | -425.69M | -994.00K |
| Financing Cash Flow | 375.76M | 375.76M | 2.12B | 1.85B | -22.16M |
Heartseed, Inc. Technical Analysis
Price Trends
Market Momentum
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:219A, the sentiment is Positive. The current price of 3010.00 is above the 20-day moving average (MA) of 2759.80, above the 50-day MA of 2550.94, and above the 200-day MA of 1977.65, indicating a bullish trend. The MACD of 134.03 indicates Negative momentum. The RSI at 65.38 is Neutral, neither overbought nor oversold. The STOCH value of 76.71 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for JP:219A.
Heartseed, Inc. Peers Comparison
Overall Rating
- JP:219A80Outperform
JP:493171Outperform
JP:334959.9Neutral
JP:435057Neutral
JP:190A43Neutral
JP:279643Neutral
Financial Indicators
| Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
| JP:219A | 80Outperform | JPY 69.13B | -102.66 | ― | ― | ― | ― |
| JP:4931 | 71Outperform | JPY 42.81B | 12.78 | ― | 2.87% | 3.38% | 32.41% |
| JP:3349 | 60Neutral | JPY 480.15B | 14.81 | ― | 1.37% | 8.99% | 3.61% |
| JP:4350 | 57Neutral | JPY 16.87B | 18.52 | ― | 2.18% | 8.19% | -25.81% |
| Sector * | 55Neutral | $6.65B | 3.83 | -15.92% | 6.20% | 10.91% | 7.18% |
| JP:190A | 43Neutral | JPY 3.79B | -2.48 | ― | ― | ― | 24.21% |
| JP:2796 | 43Neutral | JPY 5.89B | 59.48 | ― | 2.77% | 7.64% | ― |
* General Sector Average
Performance Comparison
| Show on chart | Ticker | Company Name | Price | Change | % Change |
|---|---|---|---|---|---|
| JP:219A | Heartseed, Inc. | 3010.00 | 1267.00 | 72.69% | |
| JP:2796 | Pharmarise Holdings Corp. | 505.00 | -5.26 | -1.03% | |
| JP:3349 | COSMOS Pharmaceutical Corporation | 6002.00 | -893.40 | -12.96% | |
| JP:4350 | Medical System Network Co., Ltd. | 550.00 | 63.13 | 12.97% | |
| JP:4931 | Shinnihonseiyaku Co., Ltd. | 1988.00 | -110.78 | -5.28% | |
| JP:190A | Chordia Therapeutics Inc. | 49.00 | -62.00 | -55.86% |
Heartseed, Inc. Corporate Events
Heartseed Advances HS-005 Cardiac Cell Therapy With First Ischemic Heart Disease Patient Dosed
Heartseed Inc. has dosed the first patient with severe heart failure secondary to ischemic heart disease in its EMERALD Phase I/II clinical trial of HS-005, an allogeneic iPS cell-derived cardiomyocyte spheroid therapy delivered via catheter. An Inde...
Heartseed Director Resigns After Appointment as Japan’s Digital Minister
Heartseed Inc. announced the resignation of independent board director Toshiharu Furukawa, effective September 17, 2026, following his appointment as Minister of State and Minister for Digital Transformation. The company stated it will continue to me...
Heartseed Secures ¥2 Billion Credit Line to Advance Heart Failure Cell Therapy
Heartseed Inc. has secured a 2 billion yen special overdraft facility from Sumitomo Mitsui Banking Corporation to support its push toward manufacturing and marketing approval for its lead cardiomyocyte replacement therapy, HS-001. The unsecured, one-...
Heartseed Books Subsidy-Driven Non-Operating Gain Without Changing Outlook
Heartseed Inc. reported non-operating income of 69,833 thousand yen for the six months ended June 30, 2026, driven mainly by a 52,000 thousand yen subsidy tied to the Japan Agency for Medical Research and Development’s program for basic technol...
Heartseed posts interim loss but keeps strong equity base as R&D weighs on 2026 outlook
Heartseed Inc. reported non-consolidated net sales of ¥467 million for the six months ended June 30, 2026, down from ¥1,919 million in the prior comparable period, and swung to an interim net loss of ¥554 million, versus a previous pro...
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.
Date of analysis: Sep 19, 2026