Vertex Pharmaceuticals (1VRTX) Stock Price & Analysis
1VRTX Stock Chart & Stats
- Day’s Range
- EUR 494.10 - EUR 494.10
- 52-Week Range
- EUR 316.00 - EUR 609.00
- Previous Close
- EUR 484.20
- Volume
- 1
- Average Volume (3M)
- 6
- Market Cap
- EUR 126.41B
- Enterprise Value
- EUR 120.88B
- Total Cash (Recent Filing)
- EUR 7.85B
- Total Debt (Recent Filing)
- EUR 1.98B
- Price to Earnings (P/E)
- 32.3
- Beta
- 0.06
- Next Earnings
- Nov 02, 2026 (Est.)
- EPS Estimate
- 4.3
- Next Dividend Ex-Date
- N/A
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
High Profitability And Cash Generation
Vertex converts its profitable operations into substantial cash, with free cash flow representing about 88% of net income. This supports internal funding for research, launches and strategic investment while reducing dependence on external financing over the next several quarters.
Conservative Balance Sheet
A strong equity base and currently reported zero TTM debt provide meaningful financial flexibility. Vertex can fund development, commercial expansion and shareholder returns from a position of strength, while remaining better positioned to absorb operating volatility.
Broadening Growth Platform
Growth is increasingly supported by multiple commercial products and advancing pipeline programs rather than a single new launch. Strong CF execution, rapid CASGEVY uptake and JOURNAVX expansion create additional avenues for durable revenue growth beyond the established franchise.
Bears Say
Acquisition Increases Leverage And Execution Risk
The Crinetics transaction adds a new commercial pillar but requires substantial funding and introduces integration complexity. Near-term earnings benefit is expected to be modest, while added debt and the long wait for accretion increase execution and capital-allocation risk.
Expense And Gross-margin Pressure
Investment in renal, pain and manufacturing capabilities is absorbing more of the benefit from revenue growth. Elevated operating costs and lower mix-adjusted margins could limit profit conversion in coming quarters, even if commercial expansion remains successful.
Dependence On The CF Franchise
Historical reliance on CF leaves Vertex exposed to concentration in one therapeutic franchise and the need to replace or supplement that contribution over time. New products and pipeline programs must scale successfully to make revenue diversification durable.
Vertex Pharmaceuticals News
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Vertex Pharmaceuticals Stock Smart Score
Company Description
Vertex Pharmaceuticals
Vertex Pharmaceuticals Incorporated is a leading biotechnology firm primarily focused on the discovery, advancement, and marketing of innovative treatments, particularly for cystic fibrosis (CF). The company offers a range of approved medications for CF patients, including SYMDEKO/SYMKEVI, ORKAMBI, and KALYDECO, which target specific mutations within the cystic fibrosis transmembrane conductance regulator gene. Additionally, they provide TRIKAFTA for individuals with CF aged six years and older who possess at least one F508del mutation. Beyond its established CF therapies, Vertex maintains a robust and diverse clinical pipeline. This includes VX-864, currently in Phase 2 for alpha-1 antitrypsin (AAT) deficiency; VX-147, also in Phase 2, addressing APOL1-mediated focal segmental glomerulosclerosis (FSGS) and other serious kidney conditions; VX-880, a potential treatment for Type 1 Diabetes undergoing Phase 1/2 trials; VX-548, a NaV1.8 inhibitor in Phase 2 for various forms of acute, neuropathic, and musculoskeletal pain; and CTX001, which is in Phase 3 development for severe sickle cell disease (SCD) and transfusion-dependent beta-thalassemia (TDT). The company distributes its pharmaceutical products through specialty pharmacies and distributors across the United States, while international sales are facilitated via a network of specialty distributors, retail chains, hospitals, and clinics. Vertex also engages in numerous strategic collaborations with partners such as Affinia Therapeutics, Arbor Biotechnologies, CRISPR Therapeutics, Kymera Therapeutics, Mammoth Biosciences, Moderna, Obsidian Therapeutics, Skyhawk Therapeutics, Ribometrix, Genomics plc, Merck KGaA, and X-Chem. Established in 1989, Vertex Pharmaceuticals is headquartered in Boston, Massachusetts.
- Sector
- Healthcare
- Industry
- Biotechnology
- CEO
- Reshma Kewalramani
- Employees
- 6,400
- Website
- www.vrtx.com
- Address
- 50 Northern Avenue, Boston, MA, 02210, US
Vertex Pharmaceuticals (1VRTX) Earnings & Revenues
1VRTX Company Deck
1VRTX Earnings Call
Earnings Call SentimentPositive
The call presented a largely positive commercial and clinical update: revenue and key product launches (ALYFTREK, CASGEVY, JOURNAVX) showed strong momentum, guidance was raised, multiple clinical and regulatory milestones were achieved or on track (Pove BLA accepted, AMPLITUDE/AMPLIFIED/AGLOW enrollment complete or progressing, VX‑017 IND cleared), and the Crinetics acquisition adds a new specialty pillar. Offsetting factors include higher SG&A and upcoming operating expense at the high end of guidance, gross margin pressure from product mix and manufacturing investments, short‑term revenue volatility for cell therapies and PSP‑driven gross‑to‑net impacts (normalization expected in H1 2027), and near‑term costs and debt associated with the Crinetics deal. Overall, the positive commercial execution and pipeline progress outweigh the near‑term cost and execution risks.
View all IT:1VRTX earnings summaries1VRTX Net sales Breakdown
- 85.93% TRIKAFTA/KAFTRIO
- 6.98% ALYFTREK
- 6.83% Other product revenues
- 0.26% Other revenues
1VRTX Stock 12 Month Forecast
Average Price Target
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 15 | 2 | 5 |
| Technical Analysis | 3 | 2 | 5 |
| Moving Averages | 12 | 0 | 0 |