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Inhibikase Therapeutics, Inc. (IKT)
:IKT

Inhibikase Therapeutics (IKT) AI Stock Analysis

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Inhibikase Therapeutics

(NASDAQ:IKT)

46Neutral
Inhibikase Therapeutics' stock score is primarily impacted by its poor financial performance, marked by declining revenues and persistent losses. Technical analysis paints a mixed picture, with short-term indicators slightly positive but overshadowed by longer-term negative trends. Valuation metrics indicate caution due to a negative P/E ratio. The recent leadership change provides a potential positive catalyst for future performance, but its impact remains to be seen.
Positive Factors
Financial Performance
The company raised $110M in gross proceeds, which is expected to provide sufficient financial support into 2027, enhancing the company's stability and growth potential.
Regulatory Approval
Inhibikase received IND-clearance from the FDA for the Phase 2b 702 trial of IkT-001Pro in pulmonary arterial hypertension, marking a significant milestone for the company's drug development.
Negative Factors
Earnings
Inhibikase reported 4Q24 EPS of ($0.17), which was worse than the estimated ($0.10), indicating financial underperformance.
Product Development
The company halted further development of risvodetinib and there is no clinical data yet for IkT-001Pro in PAH, leading to a Neutral rating on the stock.

Inhibikase Therapeutics (IKT) vs. S&P 500 (SPY)

Inhibikase Therapeutics Business Overview & Revenue Model

Company DescriptionInhibikase Therapeutics, Inc., a clinical stage pharmaceutical company, develops therapeutics for Parkinson's Disease (PD) and related disorders that arise inside and outside of the brain. The company's product candidates include IkT-148009, a small molecule Abelson tyrosine kinase inhibitor for use in the treatment of PD, as well as gastrointestinal complications that arise as early symptoms of PD, such as swallowing, dysphagia, neurogenic constipation, and multiple system atrophy; and IkT-001Pro, a prodrug of the anti-cancer agent Imatinib that is in preclinical development to minimize gastrointestinal side effects and for the treatment of blood and stomach cancers. It is also involved in developing various research programs for other neurological diseases. The company has research and development collaborations with The Johns Hopkins University, Arizona State University, and Michigan State University, as well as Louisiana State University. Inhibikase Therapeutics, Inc. was founded in 2008 and is headquartered in Atlanta, Georgia.
How the Company Makes MoneyInhibikase Therapeutics makes money through the development and commercialization of its pharmaceutical products. The company's revenue model is primarily based on advancing its drug candidates through clinical trials and achieving successful regulatory approvals. Key revenue streams include potential partnerships with larger pharmaceutical companies for the co-development or licensing of its therapies, as well as possible future revenues from product sales once the drugs reach the market. Additionally, the company may receive funding through research grants, collaborations, and milestone payments from strategic alliances, which help support its research and development efforts.

Inhibikase Therapeutics Financial Statement Overview

Summary
Inhibikase Therapeutics is facing significant financial challenges with diminishing total revenue, consistent net losses, and negative operating cash flow. The balance sheet is strong in terms of equity due to financing activities, but the company's reliance on external financing is concerning.
Income Statement
Inhibikase Therapeutics shows diminishing total revenue over the years, with a sharp drop to zero in the latest year. The company consistently reports negative net income, indicating ongoing losses. Margins such as EBIT and EBITDA are negative due to high expenses relative to the revenue. Revenue growth is negative when comparing to previous periods, highlighting challenges in revenue generation.
Balance Sheet
30
The company's balance sheet reflects a strong equity position relative to debt, as seen in the low debt-to-equity ratio. However, the high level of equity is primarily due to financing activities rather than retained earnings. The equity ratio is high, reflecting the company's reliance on equity financing. There is minimal debt, reducing leverage risks, but the persistent losses affect return on equity negatively.
Cash Flow
Operating cash flow remains negative, indicating the company is not generating positive cash from its core operations. While free cash flow is negative, indicating the company is spending more than it earns, there is considerable financing inflow, which supports liquidity. The ratios of cash flow to net income are unfavorable due to consistent net losses.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
0.00260.50K123.44K3.10M698.47K
Gross Profit
0.00-13.36M116.72K-8.26M-195.33K
EBIT
-28.59M-20.09M-18.13M-14.77M-2.82M
EBITDA
-28.59M-19.91M-18.12M-14.77M-2.82M
Net Income Common Stockholders
-27.52M-19.03M-17.91M-14.81M-2.88M
Balance SheetCash, Cash Equivalents and Short-Term Investments
97.54M13.25M23.05M40.75M13.95M
Total Assets
98.60M14.51M24.94M42.47M14.78M
Total Debt
110.52K622.00K351.29K248.91K319.00K
Net Debt
-56.38M-8.54M-6.84M-40.50M-13.63M
Total Liabilities
3.73M3.53M3.90M4.05M5.00M
Stockholders Equity
94.87M10.98M21.04M38.42M9.78M
Cash FlowFree Cash Flow
-19.15M-18.10M-17.59M-14.30M-1.13M
Operating Cash Flow
-19.15M-18.09M-17.35M-14.30M-1.13M
Investing Cash Flow
-37.00M11.66M-16.01M0.000.00
Financing Cash Flow
103.48M8.41M-204.77K41.09M15.06M

Inhibikase Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price2.25
Price Trends
50DMA
2.18
Positive
100DMA
2.53
Negative
200DMA
2.14
Positive
Market Momentum
MACD
0.02
Negative
RSI
55.47
Neutral
STOCH
86.66
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For IKT, the sentiment is Positive. The current price of 2.25 is above the 20-day moving average (MA) of 2.02, above the 50-day MA of 2.18, and above the 200-day MA of 2.14, indicating a bullish trend. The MACD of 0.02 indicates Negative momentum. The RSI at 55.47 is Neutral, neither overbought nor oversold. The STOCH value of 86.66 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for IKT.

Inhibikase Therapeutics Risk Analysis

Inhibikase Therapeutics disclosed 89 risk factors in its most recent earnings report. Inhibikase Therapeutics reported the most risks in the “Tech & Innovation” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Inhibikase Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
53
Neutral
$325.29M-74.36%-10.43%
52
Neutral
$5.35B3.81-42.57%2.86%17.10%1.33%
IKIKT
46
Neutral
$167.27M-52.00%-100.00%38.72%
46
Neutral
$162.63M2152.93%54.68%
45
Neutral
$170.18M-43.31%95.23%15.47%
42
Neutral
$181.28M-53.27%2.53%
38
Underperform
$163.24M-57.58%15.18%-9.47%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
IKT
Inhibikase Therapeutics
2.25
0.96
74.42%
RZLT
Rezolute
4.00
0.73
22.32%
ACIU
AC Immune SA
1.72
-0.68
-28.33%
DMAC
Diamedica Therapeutics
4.23
0.73
20.86%
TNGX
Tango Therapeutics
1.51
-6.38
-80.86%
NBTX
Nanobiotix
3.34
-2.98
-47.15%

Inhibikase Therapeutics Earnings Call Summary

Earnings Call Date:Mar 27, 2025
(Q2-2024)
|
% Change Since: -5.06%|
Next Earnings Date:May 19, 2025
Earnings Call Sentiment Neutral
The earnings call presented a mix of positive developments, such as the completion of trial enrollments and financial strengthening, alongside challenges like observed adverse events and increased expenses. The potential for significant advancements, particularly in PAH and Parkinson's disease treatments, is promising, though tempered by some operational hurdles.
Q2-2024 Updates
Positive Updates
Completion of Phase II 201 Trial Enrollment
Inhibikase Therapeutics has completed enrollment for the Phase II 201 Trial for risvodetinib in Parkinson's disease, marking a significant milestone. Top line data from the trial is expected in November.
Progress with IkT-001Pro for PAH
The company filed the IND for IkT-001Pro targeting pulmonary arterial hypertension (PAH) and plans to initiate a Phase IIb study. The market value for PAH treatments is estimated at $7.7 billion annually.
Financial Strength
Inhibikase raised $4 million from a registered direct offering and concurrent private placement, extending their cash runway into December 2024.
Decrease in Net Loss
Net loss for Q2 2024 was $5.0 million, or $0.66 per share, compared to $5.8 million, or $0.94 per share, for Q2 2023, indicating improved financial management.
Negative Updates
Adverse Events in Phase II 201 Trial
In the Phase II 201 Trial, 41 mild and 8 moderate adverse events were observed that may be related to risvodetinib treatment, with 6 participants withdrawing from the trial.
Increased SG&A Expenses
Selling, general, and administrative expenses increased to $2.0 million from $1.8 million in Q2 2023, driven by higher legal and consulting fees.
Financial Constraints Impacting Trial Timelines
Financial constraints have delayed the formal launch of the 12-month open-label extension study for risvodetinib, potentially impacting patient treatment continuity.
Company Guidance
During the Inhibikase Therapeutics Q2 2024 earnings call, executives highlighted several key metrics and developments. The company completed enrollment for the Phase II trial of risvodetinib in Parkinson's disease, expecting to report top-line data in November. They observed 49 adverse events and had six withdrawals from the trial. For their IkT-001Pro, a prodrug formulation aimed at pulmonary arterial hypertension (PAH), they filed an IND on August 9, 2024, with plans for a Phase IIb trial involving around 100 patients. Financially, Inhibikase reported a net loss of $5.0 million for the quarter, with R&D expenses decreasing by $1.5 million to $3.1 million, and a cash position of $7.9 million as of June 30, 2024. The company expects its cash runway to extend into December 2024, bolstered by raising $4 million in May from registered direct offering and concurrent private placement.

Inhibikase Therapeutics Corporate Events

Executive/Board Changes
Inhibikase Therapeutics Appoints New Chief Financial Officer
Neutral
Apr 14, 2025

Inhibikase Therapeutics has announced the resignation of Garth Lees-Rolfe as Chief Financial Officer, effective April 11, 2025. His departure was amicable, and he will continue to provide consulting services to the company until August 15, 2025. David McIntyre has been appointed as the new Chief Financial Officer effective April 14, 2025. McIntyre brings over two decades of experience in the life sciences sector, having held various executive roles in biotech and medical device companies. His appointment is expected to strengthen the company’s financial leadership and strategic direction.

Spark’s Take on IKT Stock

According to Spark, TipRanks’ AI Analyst, IKT is a Underperform.

Inhibikase Therapeutics is struggling financially, with consistent net losses and negative cash flow. The stock’s technical indicators are bearish, and the valuation is not compelling due to the negative P/E ratio. However, recent leadership changes provide a glimmer of hope for strategic improvement. The stock’s overall score reflects these concerns, with financial performance being the most significant drag on the score, mitigated slightly by positive corporate events.

To see Spark’s full report on IKT stock, click here.

Executive/Board ChangesM&A Transactions
Inhibikase Therapeutics Completes Merger with CorHepta Pharmaceuticals
Neutral
Feb 24, 2025

On February 21, 2025, Inhibikase Therapeutics completed a merger with CorHepta Pharmaceuticals, making CorHepta a wholly-owned subsidiary. The transaction involved a $15 million payment in the form of company shares, with some shares contingent on future milestones. The company also announced leadership changes, appointing Chris Cabell as President and Head of Research and Development, and Vincent Aurentz to the Board of Directors, aiming to enhance its strategic positioning in the biopharmaceutical industry.

Executive/Board ChangesBusiness Operations and Strategy
Inhibikase Therapeutics Appoints Mark Iwicki as New CEO
Positive
Feb 18, 2025

Inhibikase Therapeutics announced the resignation of Milton H. Werner as CEO and the appointment of Mark Iwicki, effective February 14, 2025. Werner’s departure was amicable, with a consulting agreement extending his service. Iwicki, a seasoned biopharmaceutical executive, brings extensive experience and is expected to advance the company’s lead product, IkT-001Pro, enhancing Inhibikase’s positioning in the cardiopulmonary therapeutic market. Additionally, Amit Munshi has been appointed as the new Chair of the Board, reflecting a strategic leadership shift aimed at driving growth and fulfilling unmet needs in PAH treatment.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.