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Hyperion DeFi (HYPD) AI Stock Analysis

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HYPD

Hyperion DeFi

(NASDAQ:HYPD)

Select Model
Rating:56Neutral
Price Target:$3.00â–²(10.29% Upside)
Action:reiterated
Date:11/13/26

The score is primarily constrained by weak cash-flow fundamentals and flagged earnings-quality/volatility concerns, despite a currently strong balance sheet. Technicals also weigh on the rating given the price is below all major moving averages with negative MACD. Offsetting these, the latest earnings call was constructive with reiterated improved guidance, early delivery of positive adjusted operating cash flow, debt repayment, and buybacks, but valuation signals are limited by a negative P/E and no dividend yield data.

Positive Factors
Adjusted Gross Profit GrowthRapid adjusted gross profit expansion and reiterated full-year guidance indicate that recently launched DeFi strategies are gaining commercial traction. If sustained, this growth can improve operating leverage, strengthen the platform’s market position, and support reinvestment across its ecosystem.
Negative Factors
Persistent Cash BurnSustained negative operating and free cash flow indicates the business has not consistently self-funded its operations despite recent adjusted cash-flow improvement. Persistent cash burn can constrain investment, increase reliance on asset sales or financing, and weaken resilience if growth slows.

Hyperion DeFi (HYPD) vs. SPDR S&P 500 ETF (SPY)

-50%-40%-30%-20%-10%0%10%20%HYPD-36.00%SPY+13.89%Dec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
Market Cap
$41.23M
Dividend Yield
―
Average Volume (3M)
463.18K
Price to Earnings (P/E)
-0.7
Beta (1Y)
3.54
Revenue Growth
452.71%
EPS Growth
90.06%
Country
US
Employees
9
Sector
Healthcare
Sector Strength
51
Industry
Asset Management - Cryptocurrency

Hyperion DeFi Business Overview & Revenue Model

Company Description

Hyperion DeFi, Inc. is a U.S. publicly listed company that is building a long-term strategic treasury of HYPE, the native token of the Hyperliquid blockchain. The company's primary objective is to provide shareholders with streamlined access to the H...

Hyperion DeFi Earnings Call Summary

Earnings Call Date:Nov 12, 2026(Q3-2026)|% Change Since:0.37%|Next Earnings Date:Apr 01, 2027
Earnings Call SentimentPositive

The call was strongly positive, with record net income, substantial adjusted gross profit growth, positive core operating earnings and adjusted operating cash flow, lower operating expenses, full repayment of legacy debt, and progress across diversified DeFi revenue streams. The main negatives were the sequential decline in HYPE token holdings, lower adjusted EBITDA and treasury gains, variability in ecosystem rewards, remaining regulatory approval requirements, and the unresolved sports prediction-market opportunity.

Positive Updates

Best Quarter to Date Under New Operating Strategy
Q3 was described as Hyperion DeFi's best quarter to date under its new operating strategy, with the highest income quarter to date and growth in core business lines supported by recently launched strategies.

Negative Updates

HYPE Treasury Tokens Declined Sequentially
Gross HYPE tokens decreased from 2.04 million in Q2 to 1.85 million in Q3, primarily because HYPE was sold to fund retirement of legacy debt.

Company Guidance

Hyperion reiterated full year 2026 adjusted gross profit guidance of $7 million to $8 million, after originally guiding to $4 million to $6 million and raising it to $5 million to $7 million; through the first 9 months of the year, it had generated $4.9 million, roughly 70% of the low end of that range. Adjusted net operating cash flow was guided to flip positive by the end of '26, which the company said it delivered in Q3, while Q3 operating expenses, excluding stock-based compensation, were within the guided range of $2.0 million to $2.25 million and core operating earnings were above the guided $0 million to $0.5 million range. The company said costs will be completely gone beginning in Q4 for certain legal and biotech-exit items, aspires to continue to reduce costs, and does not expect costs to materially increase unless there's some sort of step-wise change in the scope of what it does.

Hyperion DeFi Financial Statement Overview

Summary

Balance sheet strength is a clear positive (very low leverage and large equity), but cash flow is a major concern with deeply negative TTM operating and free cash flow and a multi-year pattern of cash burn. Income statement shows a sharp TTM profitability swing, yet the cross-statement consistency and volatility flagged in the provided analysis reduce confidence in earnings quality.

Income Statement

58Neutral

Balance Sheet

74Positive

Cash Flow

27Negative
Financial statement breakdown
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue1.91M813.46K57.34K3,787014.00M
Gross Profit1.61M510.17K-3.87M-12.22K012.40M
EBITDA40.06B-43.76M-46.21M-24.11M-26.32M-12.17M
Net Income39.59B-45.31M-49.82M-27.26M-28.01M-12.78M
Balance Sheet
Total Assets146.29B51.76M3.67M28.78M31.04M31.66M
Cash, Cash Equivalents and Short-Term Investments6.62B6.44M2.12M14.85M22.86M19.46M
Total Debt529.31M8.51M11.24M16.08M10.12M7.15M
Total Liabilities4.20B10.70M16.76M19.78M13.80M11.19M
Stockholders Equity142.09B41.06M-13.10M9.00M17.23M20.47M
Cash Flow
Free Cash Flow-8.77B-14.77M-30.28M-27.81M-25.98M-22.49M
Operating Cash Flow-8.76B-14.77M-30.12M-23.84M-25.11M-20.87M
Investing Cash Flow-4.92M-71.95M-161.48K-3.97M-874.75K-1.62M
Financing Cash Flow16.34M91.05M17.55M19.79M21.51M21.46M

Hyperion DeFi Technical Analysis

Technical Analysis SentimentNegative
Last Price2.72

Price Trends

50DMA3.33Negative
100DMA3.13Negative
200DMA3.34Negative

Market Momentum

MACD-0.18Positive
RSI42.52Neutral
STOCH30.75Neutral

Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HYPD, the sentiment is Negative. The current price of 2.72 is below the 20-day moving average (MA) of 2.89, below the 50-day MA of 3.33, and below the 200-day MA of 3.34, indicating a bearish trend. The MACD of -0.18 indicates Positive momentum. The RSI at 42.52 is Neutral, neither overbought nor oversold. The STOCH value of 30.75 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HYPD.

Hyperion DeFi Risk Analysis

Hyperion DeFi disclosed 48 risk factors in its most recent earnings report. Hyperion DeFi reported the most risks in the "Finance & Corporate" category.

Higher RiskSector Avg.Lower RiskFinance & CorporateTech & InnovationLegal & RegulatoryProductionAbility to SellMacro & Political
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy

Latest Risks Added

3 New Risks
1.The Company's deposits into the Rysk Institutional Volatility Income Vault and smart contract enabled options activity expose the Company to additional risks and earnings volatility.Q2, 2026
2.The Company's deposits into the Rysk Institutional Volatility Income Vault and smart contract enabled options activity expose the Company to additional risks and earnings volatility.Q1, 2026
3.Our ability to achieve profitability is highly dependent on the commercial success of Mydcombi and clobetasol propionate, and to the extent Mydcombi and clobetasol propionate are not successful, our business, financial condition and results of operations may be materially adversely affected and the price of our common stock may decline.Q4, 2023

Hyperion DeFi Peers Comparison

Overall Rating

UnderperformOutperform
Sector (51)

Financial Indicators

HYPD against its peers
NameOverall RatingMarket CapP/E RatioROEDividend YieldRevenue GrowthEPS Growth
HYPDHYPD56Neutral$42.11M-0.72111.28%―452.71%90.06%
SRTSSRTS54Neutral$56.14M-3.48-34.09%―-53.40%-1719.88%
Sector *51Neutral$7.86B-0.30-43.30%2.27%22.53%-2.21%
TELATELA48Neutral$42.56M-1.10425.91%―1.46%15.79%
CTSOCTSO47Neutral$16.83M-0.96-445.14%―8.64%-61.01%
BDMDBDMD42Neutral$3.33M-0.19-48.23%―――
ICCMICCM42Neutral$2.54M-0.10-174.26%―41.62%20.47%

* Healthcare Sector Average

Performance Comparison

0%100%HYPDCTSOSRTSTELAICCMBDMDDec '25Jan '26Feb '26Mar '26Apr '26May '26Jun '26Jul '26Aug '26Sep '26Oct '26Nov '26
HYPD and its peers over the selected period
Show on chartTickerCompany NamePriceChange% Change
HYPDHyperion Defi, Inc.2.72-2.29-45.71%
CTSOCytosorbents Corp5.37-7.83-59.32%
SRTSSensus Healthcare, Inc.3.22-1.10-25.46%
TELATela Bio, Inc.0.86-0.14-14.00%
ICCMIcecure Medical Ltd.0.70-20.68-96.73%
BDMDBaird Medical Investment Holdings Ltd0.11-1.16-91.57%

Hyperion DeFi Corporate Events

Stock BuybackFinancial Disclosures

Hyperion DeFi Reports Record Quarterly Results and Debt Retirement

Positive
Nov 12, 2026

Hyperion DeFi, a U.S. publicly listed decentralized-finance company building on Hyperliquid, reported results for the quarter ended September 30, 2026, on November 12, 2026. The company reported record net income of $39.6 million and adjusted EBITDA...

Business Operations and StrategyStock BuybackFinancial DisclosuresPrivate Placements and Financing

Hyperion DeFi Highlights Debt-Free Balance Sheet and Buybacks

Positive
Oct 2, 2026

On September 28, 2026, Hyperion DeFi voluntarily repaid in full all outstanding obligations under its Avenue Capital loan agreement, terminating roughly $15 million in available term loan capacity and releasing all liens and security interests on its...

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.

Date of analysis: Nov 13, 2026