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Hcw Biologics, Inc. (HCWB)
:HCWB
US Market
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HCW Biologics (HCWB) AI Stock Analysis

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HCWB

HCW Biologics

(NASDAQ:HCWB)

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Neutral 41 (OpenAI - 4o)
Rating:41Neutral
Price Target:
$4.00
▲(0.25% Upside)
HCW Biologics is struggling with financial instability and operational inefficiencies, reflected in its low financial performance score. The technical analysis indicates a bearish trend, and the valuation metrics are poor due to ongoing losses. These factors contribute to a low overall stock score, highlighting significant risks for investors.
Positive Factors
Strategic Partnerships
The partnership with Wugen provides HCW Biologics with potential revenue streams from equity interest and strengthens its strategic position in the biotech industry.
Innovative Product Pipeline
The development of HCW11-040 highlights HCW Biologics' focus on innovation in cancer therapies, potentially enhancing long-term growth through new product offerings.
Revenue from Licensing Agreements
Revenue from licensing agreements, such as with Wugen, provides a steady income stream, supporting financial stability and enabling further R&D investments.
Negative Factors
Declining Revenue
The negative revenue growth rate indicates challenges in market penetration or product sales, potentially impacting long-term financial health and operational sustainability.
High Leverage
High leverage and negative equity suggest financial instability, which could limit the company's ability to invest in growth opportunities and weather economic downturns.
Negative Cash Flow
Negative cash flow from operations indicates inefficiencies in converting revenue into cash, which may constrain the company's ability to fund operations and invest in growth.

HCW Biologics (HCWB) vs. SPDR S&P 500 ETF (SPY)

HCW Biologics Business Overview & Revenue Model

Company DescriptionHCW Biologics (HCWB) is a biotechnology company focused on the development and commercialization of innovative therapies for various diseases, particularly those related to cancer and immune disorders. The company specializes in biologics, utilizing advanced technologies to create targeted treatments that harness the body's immune system to fight diseases. HCWB operates in the healthcare sector with a commitment to improving patient outcomes through its cutting-edge research and development efforts.
How the Company Makes MoneyHCW Biologics generates revenue primarily through the development and commercialization of its proprietary therapeutic products. The company earns money by licensing its technology and products to pharmaceutical companies, receiving milestone payments, and royalties based on sales of these therapies. Additionally, HCWB may engage in collaborative partnerships with other biotech firms or research institutions to co-develop products, which can provide funding and shared resources. Grants and government funding for research initiatives may also contribute to its revenue stream, particularly in early-stage development phases.

HCW Biologics Financial Statement Overview

Summary
HCW Biologics is experiencing severe financial difficulties with declining revenues, high operational losses, and significant leverage. The negative equity and cash flow issues highlight financial instability and operational inefficiencies.
Income Statement
30
Negative
HCW Biologics has experienced declining revenue over the past year, with a negative revenue growth rate. The gross profit margin is positive but very low, indicating challenges in managing costs or pricing. The net profit margin is deeply negative, reflecting significant losses in operations, compounded by negative EBIT and EBITDA margins, which highlight inefficiencies in core business operations.
Balance Sheet
20
Very Negative
The company's balance sheet shows a high debt-to-equity ratio due to negative equity, indicating potential financial distress. The return on equity is also negative, reflecting losses. The equity ratio is negative, a sign of financial instability and potential risk for creditors. Overall, the balance sheet suggests significant leverage and financial challenges.
Cash Flow
35
Negative
HCW Biologics has negative operating cash flow, indicating cash burn from core operations. The free cash flow is also negative, showing cash outflows exceeding inflows. However, financing activities have provided a cash influx, slightly offsetting cash burn. The operating cash flow to net income ratio is negative, suggesting challenges in converting revenue into cash.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue832.84K2.57M2.84M6.72M0.004.10M
Gross Profit-515.94K959.40K560.36K2.59M-543.60K4.10M
EBITDA-11.42M-27.68M-23.58M-14.18M-12.82M-5.25M
Net Income-21.55M-30.02M-24.99M-14.72M-12.36M-5.78M
Balance Sheet
Total Assets28.91M30.24M28.51M46.81M53.51M15.40M
Cash, Cash Equivalents and Short-Term Investments2.44M4.67M3.60M32.06M36.71M8.46M
Total Debt6.42M13.69M6.30M6.41M0.00567.31K
Total Liabilities28.96M37.01M15.05M9.38M2.32M1.00M
Stockholders Equity-51.97K-6.77M13.46M37.43M51.19M14.40M
Cash Flow
Free Cash Flow-12.71M-14.49M-28.72M-20.66M-11.02M-10.62M
Operating Cash Flow-12.56M-14.23M-22.51M-10.39M-10.98M-10.43M
Investing Cash Flow-150.47K-261.62K3.80M14.71M-35.02M-186.68K
Financing Cash Flow13.99M15.57M-14.53K6.27M49.27M11.72M

HCW Biologics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3.99
Price Trends
50DMA
4.26
Negative
100DMA
4.44
Negative
200DMA
8.07
Negative
Market Momentum
MACD
-0.08
Positive
RSI
45.76
Neutral
STOCH
1.98
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HCWB, the sentiment is Negative. The current price of 3.99 is below the 20-day moving average (MA) of 4.07, below the 50-day MA of 4.26, and below the 200-day MA of 8.07, indicating a bearish trend. The MACD of -0.08 indicates Positive momentum. The RSI at 45.76 is Neutral, neither overbought nor oversold. The STOCH value of 1.98 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HCWB.

HCW Biologics Risk Analysis

HCW Biologics disclosed 48 risk factors in its most recent earnings report. HCW Biologics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

HCW Biologics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
$8.67M-61.65%-80.31%-293.92%
$8.79M-0.78-43.39%-100.00%49.47%
$7.86B-0.30-43.30%2.27%22.53%-2.21%
$8.14M-0.41-146.46%24.30%
$9.13M-2.01-51.83%-2.94%34.52%
$8.43M-78.77%61.32%
$7.54M-0.2191.46%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HCWB
HCW Biologics
3.92
-14.12
-78.27%
KPRX
Kiora Pharmaceuticals
2.56
-1.48
-36.63%
MTNB
Matinas BioPharma
1.60
-1.60
-50.00%
XBIO
Xenetic Biosciences
4.01
0.09
2.30%
ADXN
Addex Therapeutics
9.60
-1.41
-12.81%
CLDI
Calidi Biotherapeutics
1.54
-12.62
-89.12%

HCW Biologics Corporate Events

Delistings and Listing ChangesRegulatory Filings and Compliance
HCW Biologics Granted Nasdaq Compliance Extension
Neutral
Oct 16, 2025

On August 19, 2025, HCW Biologics Inc. received notice from Nasdaq that it was non-compliant with the Equity Rule for continued listing. Following a hearing on September 25, 2025, the Nasdaq Hearings Panel granted the company an extension to regain compliance, requiring it to meet all listing rules by February 16, 2026. The company must also notify Nasdaq of significant events affecting compliance and file necessary documentation for review.

The most recent analyst rating on (HCWB) stock is a Hold with a $4.50 price target. To see the full list of analyst forecasts on HCW Biologics stock, see the HCWB Stock Forecast page.

Business Operations and Strategy
HCW Biologics Extends License Fee Payment Deadline
Neutral
Sep 5, 2025

HCW Biologics Inc. and WY Biotech Co., Ltd. have agreed to extend the payment date for a $7.0 million upfront license fee under their worldwide exclusive license agreement to September 30, 2025. However, WY Biotech has not finalized necessary agreements with its partners and may not meet the new deadline, prompting ongoing negotiations for further revisions to the agreement.

The most recent analyst rating on (HCWB) stock is a Hold with a $4.50 price target. To see the full list of analyst forecasts on HCW Biologics stock, see the HCWB Stock Forecast page.

Delistings and Listing ChangesRegulatory Filings and Compliance
HCW Biologics Faces Nasdaq Non-Compliance Notice
Negative
Aug 19, 2025

On June 26, 2025, HCW Biologics Inc. announced that it had received formal notice from Nasdaq confirming its compliance with the Equity Rule for continued listing on the Nasdaq Capital Market. However, the company remains under a Panel Monitor until June 23, 2026, and must request a hearing to address any future non-compliance. On August 19, 2025, HCW Biologics was notified of non-compliance as of June 30, 2025, risking suspension of its securities from trading on Nasdaq unless a hearing is requested by August 26, 2025. The company plans to request a hearing to stay the suspension and is exploring options to regain compliance, though there is no assurance of success.

The most recent analyst rating on (HCWB) stock is a Hold with a $4.00 price target. To see the full list of analyst forecasts on HCW Biologics stock, see the HCWB Stock Forecast page.

HCW Biologics Delays Q2 10-Q Filing
Aug 15, 2025

HCW Biologics Inc. has announced a delay in filing its Form 10-Q (Quarter Report) for the financial period ending on June 30, 2025. The primary reason for this delay is the additional time required to prepare the financial statements for the quarter. The company has assured stakeholders that the report will be filed within the five-day grace period allowed by the Securities Exchange Act of 1934. HCW Biologics anticipates significant changes in its financial results compared to the previous year, largely due to a substantial decrease in legal fees from $10.4 million in Q2 2024 to $142,452 in Q2 2025, following the settlement of a long-running arbitration. The notification was signed by Rebecca Byam, the Chief Financial Officer, who confirmed the company’s commitment to compliance and timely filing.

The most recent analyst rating on (HCWB) stock is a Buy with a $3.00 price target. To see the full list of analyst forecasts on HCW Biologics stock, see the HCWB Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
HCW Biologics Amends Equity Purchase Agreement
Neutral
Aug 15, 2025

On August 14, 2025, HCW Biologics Inc. and Square Gate Capital Master Fund, LLC- Series 4 amended their Equity Purchase Agreement to allow multiple purchases and sales of shares on the same trading day. This amendment could enhance the company’s financial flexibility by enabling more dynamic trading of its shares, potentially impacting its market positioning and stakeholder interests.

The most recent analyst rating on (HCWB) stock is a Buy with a $3.00 price target. To see the full list of analyst forecasts on HCW Biologics stock, see the HCWB Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 17, 2025