Clinical Trial EnrollmentSome investors remain cautious about GOSS' ability to enroll their target PAH patient population in light of Winrevair's approval in the US.
Clinical TrialsNeither an improvement in PVR nor in the 6-minute walk test (6MWT) was seen with treatment with AV-101 vs. placebo, which resulted in missing both the primary and secondary endpoints of the trial.
Market CompetitionSkeptical that acceleration of that path forward (even if it is the more attractive of the potential pivotal studies) is enough to overcome the backdrop of poor optics given what is expected to be a compelling Winrevair launch and limited GOSS catalyst flow over the next 12 months.