Ultragenyx Pharmaceutical (0LIF) Share Price & Analysis
0LIF Stock Chart & Stats
- Day’s Range
- $15.88 - $17.41
- 52-Week Range
- $12.87 - $41.50
- Previous Close
- $17.44
- Volume
- N/A
- Average Volume (3M)
- 9,532
- Market Cap
- $1.69B
- Enterprise Value
- $2.45B
- Total Cash (Recent Filing)
- $266.00M
- Total Debt (Recent Filing)
- $1.19B
- Price to Earnings (P/E)
- ―
- Beta
- 0.96
- Next Earnings
- Feb 18, 2027 (Est.)
- EPS Estimate
- -0.71
- Next Dividend Ex-Date
- N/A
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
Revenue Growth And Gross Margin
Strong revenue expansion combined with high gross margins indicates growing commercial adoption of Ultragenyx’s rare-disease medicines and attractive product economics. If sustained, this profile can support reinvestment, improve operating leverage, and provide a durable foundation for eventual profitability.
Expanded Approved Product Portfolio
Adding two gene therapies broadens the commercial platform and increases the number of products capable of contributing to future growth. The approvals also strengthen Ultragenyx’s position in high-need genetic diseases, while active treatment-center preparation supports eventual market adoption.
Nondilutive Capital And Profitability Plan
The PRV proceeds provide substantial nondilutive funding, while planned R&D reductions and continued product growth offer a defined route toward lower cash consumption. Reaching the 2027 targets would improve financial flexibility and reduce reliance on future equity financing.
Bears Say
Deep Ongoing Losses
Persistent deep losses show that commercial growth has not yet translated into sustainable earnings under the current cost structure. This limits internally generated capital, increases dependence on execution and expense reductions, and leaves profitability sensitive to launch timing and pipeline outcomes.
Significant Cash Burn
Large recurring operating and free-cash-flow outflows indicate that the business is not yet self-funding. Continued burn can constrain investment choices and increase financing sensitivity, particularly if new product launches or cost reductions take longer than management expects to deliver.
Negative Equity And Balance-Sheet Uncertainty
Negative equity reflects accumulated losses that have materially weakened the capital base and reduced financial flexibility. The differing debt figures add uncertainty to the balance-sheet picture, increasing sensitivity to financing conditions until sustained profitability or recapitalization improves resilience.
Ultragenyx Pharmaceutical News
Ultragenyx’s GTX-102 Angelman Syndrome Study Terminated: What Investors Should Know
Ultragenyx Pharmaceutical, Inc. ($RARE) announced an update on their ongoing clinical study. Study Overview: Ultragenyx’s Phase 3 study, officially titled “A Phase 3, Randomized, Double-blind, Sham-controlled Study Investigating the Efficacy
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Ultragenyx Pharmaceutical Stock Smart Score
Company Description
Ultragenyx Pharmaceutical
Ultragenyx Pharmaceutical Inc. is a biopharmaceutical firm dedicated to discovering, developing, and commercializing innovative treatments for rare and ultra-rare genetic conditions. Its operations span North America, Europe, and other international markets. The company's portfolio of marketed biologic products addresses several serious diseases. This includes Crysvita (burosumab), an antibody that targets fibroblast growth factor 23, used to treat X-linked hypophosphatemia and tumor-induced osteomalacia. Mepsevii offers enzyme replacement therapy for both pediatric and adult patients suffering from Mucopolysaccharidosis VII. Dojolvi is available for individuals with long-chain fatty acid oxidation disorders, while Evkeeza (evinacumab) provides a treatment option for homozygous familial hypercholesterolemia. Ultragenyx also boasts a robust pipeline of investigational therapies. Notable candidates include DTX401, an adeno-associated virus 8 (AAV8) gene therapy for glycogen storage disease type Ia, and DTX301, another AAV8 gene therapy aimed at ornithine transcarbamylase deficiency. Other promising developments feature UX143, a human monoclonal antibody for osteogenesis imperfecta; GTX-102, an antisense oligonucleotide designed for Angelman syndrome; UX701, targeting Wilson disease; and UX053, in development for glycogen storage disease type III. To advance its research and development efforts, Ultragenyx Pharmaceutical Inc. maintains strategic collaboration and licensing agreements with numerous partners, such as Kyowa Kirin Co., Ltd., Saint Louis University, REGENXBIO Inc., Bayer Healthcare LLC, GeneTx, Mereo, University of Pennsylvania, Arcturus Therapeutics Holdings Inc., Solid Biosciences Inc., and Daiichi Sankyo Co., Ltd. The company was founded in 2010 and operates from its headquarters in Novato, California.
- Sector
- Healthcare
- Industry
- Biotechnology
- CEO
- Emil D. Kakkis
- Employees
- 1,371
- Website
- www.ultragenyx.com
- Address
- 60 Leveroni Court, Novato, CA, 94949, US
Ultragenyx Pharmaceutical (0LIF) Earnings & Revenues
0LIF Earnings Call
Earnings Call SentimentNeutral
The call had substantial positive developments, including two first-ever gene therapy approvals, strong demand and launch preparation, growth across established products, approximately $350 million in nondilutive proceeds, and reaffirmed 2027 profitability expectations. These were balanced by the GTX-102 Phase 3 failure, termination of UX701, a roughly 20% workforce reduction, restructuring charges, and uncertainty around the setrusumab regulatory path. Overall sentiment was mixed and balanced.
View all GB:0LIF earnings summaries0LIF Stock 12 Month Forecast
Average Price Target
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 4 | 5 | 13 |
| Technical Analysis | 4 | 5 | 1 |
| Moving Averages | 0 | 0 | 12 |










