Valerio Therapeutics (C4X) Stock Price & Analysis
C4X Stock Chart & Stats
- Day’s Range
- EUR 0.45 - EUR 0.50
- 52-Week Range
- EUR 0.06 - EUR 0.93
- Previous Close
- EUR 0.40
- Volume
- 0
- Average Volume (3M)
- 783
- Market Cap
- EUR 269.62M
- Enterprise Value
- EUR 77.01T
- Total Cash (Recent Filing)
- EUR 656.00K
- Total Debt (Recent Filing)
- EUR 12.84M
- Price to Earnings (P/E)
- ―
- Beta
- 0.60
- Next Earnings
- N/A
- EPS Estimate
- N/A
- Next Dividend Ex-Date
- N/A
- Dividend Yield
- N/A
Bulls Say, Bears Say
Bulls Say
Revenue Recovery
The sharp 2025 revenue rebound indicates improving activity across Valerio Therapeutics’ development programs after a stagnant prior year. If maintained, stronger revenue can support research investment, improve operating leverage, and provide a more durable base for future partnering or financing opportunities.
Gross Margin
Sustained gross margins of roughly 67–71% are favorable for a clinical-stage biotechnology model because incremental development-related revenue can retain meaningful contribution after direct costs. Maintaining this profile would improve the economics of future collaborations, licensing income, or eventual product commercialization.
Cash Flow Improvement
The return to positive operating and free cash flow in 2025 marks a meaningful improvement from several years of sizable cash burn. Although not yet proven consistent, internally generated cash can reduce near-term dependence on external financing and help fund ongoing oncology research activities.
Bears Say
Persistent Net Losses
Valerio Therapeutics remains loss-making despite the 2025 revenue improvement, showing that current activities have not yet produced consistent earnings power. Continued net losses can consume capital, limit financial resilience, and require additional funding before oncology programs generate substantial partnering or commercial returns.
High Leverage
Debt materially exceeds the company’s equity base, leaving Valerio Therapeutics with constrained financial flexibility. Elevated leverage can increase financing pressure, reduce room to absorb setbacks in clinical development, and make it harder to allocate capital between research programs and balance-sheet needs over the next several quarters.
Volatile Cash Generation
The 2025 cash-flow improvement has not yet demonstrated durability because free cash flow was highly volatile and fell sharply versus the preceding period as reported. A return to heavier research spending or renewed cash burn could therefore recreate dependence on equity issuance or other external financing.
Valerio Therapeutics News
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Company Description
Valerio Therapeutics
Headquartered in Paris, France, and founded in 1997, Valerio Therapeutics S.A. (known as Onxeo SA until June 2023) is a clinical-stage biotechnology company dedicated to the global research and development of oncology treatments. Their focus is on targeting the DNA repair processes crucial for tumor survival. The company's offerings include Beleodaq, an approved medication for peripheral T-cell lymphoma. Their development pipeline features AsiDNA, which is progressing through Phase 1 clinical trials for metastatic melanoma and is also being evaluated for relapsed ovarian cancer through a research collaboration with Gustave Roussy. Furthermore, Valerio Therapeutics is advancing OX401, a preclinical program targeting DNA damage response and immuno-oncology, along with its proprietary platON decoy oligonucleotide platform. The firm also holds a licensing agreement with Acrotech Biopharma LLC.
- Sector
- Healthcare
- Industry
- Biotechnology
- CEO
- Gilles Besin
- Employees
- 41
- Website
- valeriotx.com
- Address
- 49, Bd du Général Martial Valin, Paris, IF, 75015, FR
Valerio Therapeutics (C4X) Earnings & Revenues
Technical Analysis
Overall Consensus
| Indicator | Bullish | Neutral | Bearish |
|---|---|---|---|
| Overall Consensus | 11 | 6 | 5 |
| Technical Analysis | 3 | 6 | 1 |
| Moving Averages | 8 | 0 | 4 |



