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Biofrontera AG (DE:B8FK)
XETRA:B8FK
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Biofrontera (B8FK) AI Stock Analysis

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DE:B8FK

Biofrontera

(XETRA:B8FK)

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Neutral 50 (OpenAI - Gpt-5.6Sol)
Rating:50Neutral
Price Target:
€3.50
▲(38.34% Upside)
Action:Reiterated
Date:09/26/26
The score is held back primarily by weak financial performance—especially ongoing cash burn and persistent losses—despite low leverage. Technicals are a near-term positive (price above key moving averages with positive MACD), but the extremely overbought RSI raises reversal risk. Valuation is difficult to support with a negative P/E and no dividend yield data.
Positive Factors
Strong Gross Margin
An approximately 83% gross margin indicates the products retain substantial economics after direct costs. If maintained, this margin can provide a foundation for funding commercial activity and eventually converting prescription demand into operating profitability despite current losses.
Negative Factors
Persistent Cash Burn
Ongoing negative operating and free cash flow means the core business is consuming cash rather than funding itself. Continued burn can increase reliance on external financing, constrain investment in growth, and raise the risk that additional capital is needed before profitability is reached.
Read all positive and negative factors
Positive Factors
Negative Factors
Strong Gross Margin
An approximately 83% gross margin indicates the products retain substantial economics after direct costs. If maintained, this margin can provide a foundation for funding commercial activity and eventually converting prescription demand into operating profitability despite current losses.
Read all positive factors

Biofrontera (B8FK) vs. iShares MSCI Germany ETF (EWG)

Biofrontera Business Overview & Revenue Model

Company Description
Biofrontera AG operates as a biopharmaceutical company specializing in dermatology. It conducts research, development, and commercialization of skin-related products across Germany, Spain, the United Kingdom, the broader European continent, the Un...
How the Company Makes Money
Biofrontera makes money primarily by selling prescription dermatology products and associated photodynamic therapy (PDT) equipment into clinical channels. The core revenue stream historically has been product sales of Ameluz (topical gel used as a...

Biofrontera Financial Statement Overview

Summary
Overall fundamentals are weak. Income statement performance is pressured by volatile revenue (large drop after 2023) and continued net losses despite strong gross margin (~83% in 2025). Cash flow is the biggest drag, with negative operating and free cash flow in 2025 (~-4.4M / ~-4.45M) continuing a multi-year cash burn pattern. The balance sheet helps (very low leverage; debt-to-equity ~0.04), but shrinking equity and negative ROE (~-27%) keep the financial score low.
Income Statement
38
Negative
Balance Sheet
67
Positive
Cash Flow
30
Negative
BreakdownTTMDec 2025Dec 2024Mar 2024Mar 2023Mar 2022
Income Statement
Total Revenue32.25M13.19M12.18M32.25M25.74M28.79M
Gross Profit26.00M10.91M10.12M25.37M20.98M24.87M
EBITDA-172.00K-560.00K-301.00K5.57M2.34M-12.59M
Net Income-369.00K-3.96M-4.35M-369.00K-44.17M37.75M
Balance Sheet
Total Assets30.73M20.64M30.15M30.73M32.73M76.13M
Cash, Cash Equivalents and Short-Term Investments3.08M3.62M3.28M3.08M6.38M6.91M
Total Debt1.15M626.00K765.00K1.15M1.50M3.30M
Total Liabilities10.75M5.80M11.30M10.75M12.39M18.70M
Stockholders Equity19.98M14.90M18.86M19.98M20.34M57.43M
Cash Flow
Free Cash Flow772.00K-4.45M-2.75M-2.83M-4.88M29.81M
Operating Cash Flow772.00K-4.40M-2.54M-1.92M-3.90M30.44M
Investing Cash Flow0.005.33M-210.00K-912.00K-981.00K-42.26M
Financing Cash Flow0.00-452.00K2.79M-467.00K4.34M2.18M

Biofrontera Technical Analysis

Technical Analysis Sentiment
Positive
Last Price2.53
Price Trends
50DMA
2.59
Positive
100DMA
2.50
Positive
200DMA
2.52
Positive
Market Momentum
MACD
0.28
Negative
RSI
67.86
Neutral
STOCH
47.84
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DE:B8FK, the sentiment is Positive. The current price of 2.53 is below the 20-day moving average (MA) of 2.72, below the 50-day MA of 2.59, and above the 200-day MA of 2.52, indicating a bullish trend. The MACD of 0.28 indicates Negative momentum. The RSI at 67.86 is Neutral, neither overbought nor oversold. The STOCH value of 47.84 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for DE:B8FK.

Biofrontera Peers Comparison

Overall Rating
UnderperformOutperform
Sector (55)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
67
Neutral
€761.53M15.6919.49%1.75%4.42%35.68%
65
Neutral
€1.93B14.2122.38%2.24%0.39%38.58%
63
Neutral
€58.70B25.408.08%1.59%-0.40%-17.22%
55
Neutral
$6.65B3.83-15.92%6.20%10.91%7.18%
50
Neutral
€21.15M-1.88-127.78%―27.97%-1432.58%
43
Neutral
€120.70M-3.69444.89%―77.97%-41.49%
41
Neutral
€499.22M-2.58-26.46%―-7.72%-26.61%
* General Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DE:B8FK
Biofrontera
3.50
0.79
29.15%
DE:EUZ
Eckert & Ziegler Strahlen und Medizintechnik
12.55
-4.95
-28.28%
DE:EVT
Evotec
2.86
-3.21
-52.88%
DE:MRK
Merck KGaA
138.45
33.26
31.62%
DE:HPHA
Heidelberg Pharma AG
2.58
-0.38
-12.84%
DE:DMP
Dermapharm Holding SE
39.35
7.45
23.36%

Biofrontera Corporate Events

Business Operations and StrategyDelistings and Listing Changes
Biofrontera Plans Move from Prime Standard to Frankfurt’s Scale Segment
Neutral
Jul 28, 2026
Biofrontera AG’s management board, with supervisory board approval, has decided to prepare a transfer of its stock exchange listing from the regulated market’s Prime Standard to the Scale segment of the Frankfurt Stock Exchange’s...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 26, 2026