Cyclophosphamide, Fludarabine, 131I-Apamistamab, Total Body Irradiation (Tbi), Allogeneic Hematopoietic Stem Cell Transplant (Hsct)
Acute Myeloid Leukemia, Acute Myelogenous Leukemia, Acute Leukemia, Myeloid Leukemia, Myelogenous Leukemia, Myelogenous Leukemia, Acute, Acute Myeloid Leukemia, In Relapse, Myelogenous Leukemia In Relapse, Transplant-Related Disorder, Allogeneic Disease, Refractory Aml
Phase II/III
Not Yet Recruiting
Radioimmunotherapy Conditioning With 131I- Apamistamab for Allogeneic Transplant in Relapse/Refractory AML (RADAR)
Aug 28, 2025
Venetoclax, Azacitidine, Lintuzumab-Ac225
Acute Myeloid Leukemia, Relapsed Adult Aml
Phase I/II
Withdrawn
Venetoclax, Azacitidine, and Lintuzumab-Ac225 in AML Patients
Apr 17, 2019
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Venetoclax, Spironolactone, Lintuzumab-Ac225
Acute Myeloid Leukemia, Relapsed Adult Aml
Phase I/II
Unknown
Venetoclax and Lintuzumab-Ac225 in AML Patients
Mar 06, 2019
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Lintuzumab Ac 225
Refractory Multiple Myeloma
Phase I
Terminated
A Phase I Study of Lintuzumab-Ac225 in Patients With Refractory Multiple Myeloma
Dec 12, 2016
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Iomab-B, Conventional Care, Hct
Acute Myeloid Leukemia, Leukemia, Myeloid, Acute, Acute Myelogenous Leukemia, Aml, Leukemia, Acute Myeloid, Myeloid Leukemia, Acute, Leukemia, Acute Myelogenous, Myelogenous Leukemia, Acute, Bone Marrow Transplant
Phase III
Active Not Recruiting
Study of Iomab-B vs. Conventional Care in Older Subjects With Active, Relapsed or Refractory Acute Myeloid Leukemia
Jan 22, 2016
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Spironolactone, Cytarabine (Phase 1 Only), Lintuzumab-Ac225, Furosemide (Phase 1 Only)
Aml
Phase I/II
Completed
Lintuzumab-Ac225 in Older Acute Myeloid Leukemia (AML) Patients
Oct 07, 2015
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Actinium Pharmaceuticals (7AY1) have in its pipeline
7AY1 is currently developing the following drugs: Cyclophosphamide, Fludarabine, 131I-Apamistamab, Total Body Irradiation (Tbi), Allogeneic Hematopoietic Stem Cell Transplant (Hsct), Venetoclax, Azacitidine, Lintuzumab-Ac225, Venetoclax, Spironolactone, Lintuzumab-Ac225. These drug candidates are in various stages of clinical development as the company works toward FDA approval.