Aav2-Haqp1
Grade 2 And 3 Late Xerostomia Caused By Radiotherapy For Cancers Of The Upper Aerodigestive Tract, Excluding The Parotid Glands
Phase II
Enrolling By Invitation
Long-term Follow-up of Gene Therapy for Radiation-Induced Xerostomia
Aug 05, 2024
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Aav2-Haqp1 Concentration 1, Aav2-Haqp1 Concentration 2, Aav2-Haqp1 Concentration 3, Aav2-Haqp1 Concentration 4
Grade 2 And 3 Late Xerostomia Caused By Radiotherapy For Cancers Of The Upper Aerodigestive Tract, Excluding The Parotid Glands
Phase II
Recruiting
A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia
Jun 22, 2023
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Aav-Gad
Parkinson's Disease
Phase I/II
Active Not Recruiting
Long-term Follow-up of Glutamic Acid Decarboxylase (GAD) Gene Transfer in Parkinson's Disease
May 30, 2023
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Aav-Gad Low Dose, Aav-Gad High Dose, Sham Surgery
Parkinson's Disease
Phase I/II
Completed
A Double-blind Study to Evaluate the Safety of Glutamic Acid Decarboxylase Gene Transfer in Parkinson's Participants
Oct 12, 2022
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Aav2haqp1
Squamous Cell Head And Neck Cancer, Radiation Induced Xerostomia, Salivary Hypofunction
Phase I
Active Not Recruiting
Safety of a Single Administration of AAV2hAQP1, an Adeno-Associated Viral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in People With Irradiation-Induced Parotid Salivary Hypofunction
May 14, 2015
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Meiragtx Holdings Plc (328) have in its pipeline
328 is currently developing the following drugs: Aav2-Haqp1, Aav2-Haqp1 Concentration 1, Aav2-Haqp1 Concentration 2, Aav2-Haqp1 Concentration 3, Aav2-Haqp1 Concentration 4, Aav-Gad. These drug candidates are in various stages of clinical development as the company works toward FDA approval.