2LB Stock Chart & Stats
€7.30
-€0.05(-1.01%)
At close: 4:00 PM EDT
€7.30
-€0.05(-1.01%)
Day’s Range― - ―
52-Week Range€1.59 - €14.88
Previous CloseN/A
Volume0.00
Average Volume (3M)1.05K
Market Cap
€6.02B
Enterprise Value€1.62B
Total Cash (Recent Filing)€297.67M
Total Debt (Recent Filing)€46.00M
Price to Earnings (P/E)―
Beta-0.45
Next Earnings
Nov 05, 2026EPS Estimate
-0.08Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-0.73
Shares Outstanding452,971,440
10 Day Avg. Volume509
30 Day Avg. Volume1,051
Financial Highlights & Ratios
PEG Ratio0.17
Price to Book (P/B)1.40
Price to Sales (P/S)3.70
P/FCF Ratio-2.90
Enterprise Value/Market CapN/A
Enterprise Value/RevenueN/A
Enterprise Value/Gross ProfitN/A
Enterprise Value/EbitdaN/A
Forecast
1Y Price Target
€12.91Price Target Upside76.90% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering10
EPS Forecast (FY)-0.4
Revenue Forecast (FY)€369.26M
Bulls Say, Bears Say
Bulls Say
Commercial Growth And Margin ExpansionRapid revenue growth and sharply improved gross margin indicate that AMTAGVI is gaining commercial traction while the operating model scales. If patient volumes and manufacturing efficiency continue improving, the company should have increasing capacity to fund expansion and move toward sustainable profitability.
Differentiated TIL Platform And PipelineThe TIL platform is extending beyond melanoma into lung cancer and other solid tumors, creating potential growth avenues from the same therapeutic technology. Biomarker selection and planned registrational studies could improve efficacy, broaden indications, and reinforce Iovance’s competitive position.
Low Leverage And Extended Cash RunwayVery low leverage reduces mandatory financing pressure as Iovance expands its commercial infrastructure and advances clinical programs. The sizable cash position and stated runway provide time to execute on growth initiatives without relying immediately on substantial debt or equity funding.
Bears Say
Persistent Operating LossesThe business has not yet established a sustainable earnings base, because revenue growth still does not cover operating expenses. Continued losses could pressure equity over time and make successful commercial execution, margin expansion, and disciplined spending essential to reaching profitability.
Negative Operating And Free Cash FlowOngoing cash burn means Iovance must rely on improving operations or external funding to sustain commercialization and clinical development. Even with improved burn versus prior years, fluctuating outflows can reduce financial flexibility before the company achieves consistent positive cash generation.
Early-Stage Clinical Evidence RiskPromising response rates in additional indications remain statistically fragile because they are based on very small patient cohorts. Larger and more mature studies must confirm durability, safety, and efficacy before these programs can support approvals or materially diversify revenue.
Iovance Biotherapeutics News
2LB FAQ
What was Iovance Biotherapeutics Inc’s price range in the past 12 months?
Iovance Biotherapeutics Inc lowest stock price was €1.59 and its highest was €14.88 in the past 12 months.
What is Iovance Biotherapeutics Inc’s market cap?
Iovance Biotherapeutics Inc’s market cap is €6.02B.
When is Iovance Biotherapeutics Inc’s upcoming earnings report date?
Iovance Biotherapeutics Inc’s upcoming earnings report date is Nov 05, 2026 which is in 6 days.
How were Iovance Biotherapeutics Inc’s earnings last quarter?
Iovance Biotherapeutics Inc released its earnings results on Aug 06, 2026. The company reported -€0.098 earnings per share for the quarter, beating the consensus estimate of -€0.119 by €0.021.
Is Iovance Biotherapeutics Inc overvalued?
According to Wall Street analysts Iovance Biotherapeutics Inc’s price is currently Undervalued.
Does Iovance Biotherapeutics Inc pay dividends?
Iovance Biotherapeutics Inc does not currently pay dividends.
What is Iovance Biotherapeutics Inc’s EPS estimate?
Iovance Biotherapeutics Inc’s EPS estimate is -0.08.
How many shares outstanding does Iovance Biotherapeutics Inc have?
Iovance Biotherapeutics Inc has 452,971,440 shares outstanding.
What happened to Iovance Biotherapeutics Inc’s price movement after its last earnings report?
Iovance Biotherapeutics Inc reported an EPS of -€0.098 in its last earnings report, beating expectations of -€0.119. Following the earnings report the stock price went up 45.845%.
Which hedge fund is a major shareholder of Iovance Biotherapeutics Inc?
Currently, no hedge funds are holding shares in DE:2LB
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Iovance Biotherapeutics Stock Smart Score
Outperform
1
2
3
4
5
6
7
8
9
10
Analyst Consensus
Strong Buy
Average Price Target:
€12.91 (76.90% Upside)
€12.91 (76.90% Upside)
Blogger Sentiment
Bullish
DE:2LB Sentiment 90%
Sector Average 65%
Sector Average 65%
News Sentiment
Very Bullish
Bullish news 100%
Bearish news 0%
Bearish news 0%
Technicals
SMA
Positive
20 days / 200 days
Momentum
576.25%
12-Months-Change
Fundamentals
Return on Equity
-40.51%
Trailing 12-Months
Asset Growth
0.89%
Trailing 12-Months
Learn more about TipRanks Smart Score
Company Description
Iovance Biotherapeutics Inc
Iovance Biotherapeutics, Inc., a biotechnology firm currently in the clinical development stage, is committed to discovering and bringing to market cancer immunotherapy solutions. Its core mission involves leveraging the patient's own immune system to effectively combat and eradicate cancerous cells. The company is presently conducting six Phase 2 clinical trials. These include study C-144-01, evaluating its primary experimental compound, lifileucel, for individuals with advanced melanoma. Another trial, C-145-04, is assessing lifileucel's potential for treating cervical cancer that is recurrent, metastatic, or persistent. Additionally, investigational product LN-145 is undergoing evaluation in trial C-145-03 for recurrent and/or metastatic head and neck squamous cell carcinoma. Iovance Biotherapeutics, Inc. maintains strategic alliances and licensing arrangements with several distinguished entities, including H. Lee Moffitt Cancer Center, M.D. Anderson Cancer Center, Ohio State University, the Centre hospitalier de l'Université de Montreal, Cellectis S.A., and Novartis Pharma AG. Established in 2007, the company was previously known as Lion Biotechnologies, Inc. It adopted its current name, Iovance Biotherapeutics, Inc., in June 2017. Its corporate offices are located in San Carlos, California.
2LB Earnings Call
Q2 2026
0:00 / 0:00
Earnings Call Sentiment|Positive
The call conveyed strong commercial execution and meaningful operational progress: record revenue ($99.3M), a best-ever 56% gross margin, accelerating Amtagvi uptake (~$91M revenue, +51% sequential and +68% YoY), expanding ATC footprint (>95 ATCs), and important pipeline/regulatory milestones (LUN-202 near-complete enrollment, SARATOGA Fast Track). Key challenges include limited sample sizes in some early efficacy readouts, pending international reimbursement/approvals, near-term guidance review, and the need to sustain funding for continued scale and trials. On balance, the positive commercial momentum, margin expansion, pipeline advancement, and disciplined cost management significantly outweigh the near-term uncertainties.View all DE:2LB earnings summaries2LB Stock 12 Month Forecast
Average Price Target
€12.91
▲(76.90% Upside)
Technical Analysis
Nektar Therapeutics
―
Arcus Biosciences
―
Immatics
―
Nuvation Bio
―
Immunocore Holdings
―










