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Cue Biopharma (CUE)
NASDAQ:CUE
US Market
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Cue Biopharma (CUE) AI Stock Analysis

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CUE

Cue Biopharma

(NASDAQ:CUE)

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Neutral 48 (OpenAI - 5.2)
Rating:48Neutral
Price Target:
$27.00
▼(-15.94% Downside)
Action:Reiterated
Date:08/04/26
The score is primarily held back by weak financial performance—large losses and persistent cash burn despite improving revenue and strong gross margins. Technicals also point to a soft near-term trend (below key moving averages with negative MACD). Offsetting these, recent corporate actions—particularly the $50M private placement and leadership upgrades—support liquidity and execution capacity, modestly lifting the overall assessment.
Positive Factors
Revenue Growth & Margins
Sustained revenue growth (+19.2% TTM) combined with very high gross margins (~72.6%) indicates the company records revenue with favorable unit economics. Over months this supports more efficient use of R&D spend, an ability to scale collaborative revenue, and a clearer path to narrowing operating losses if growth persists.
Negative Factors
Cash Burn
Persistent negative operating and free cash flow (~ -$24.6M TTM) signals ongoing funding requirements to sustain operations. Absent accelerating revenue or repeat non-dilutive funding, continued burn increases reliance on financings, raising dilution risk and potentially constraining progress on costly clinical trials over the medium term.
Read all positive and negative factors
Positive Factors
Negative Factors
Revenue Growth & Margins
Sustained revenue growth (+19.2% TTM) combined with very high gross margins (~72.6%) indicates the company records revenue with favorable unit economics. Over months this supports more efficient use of R&D spend, an ability to scale collaborative revenue, and a clearer path to narrowing operating losses if growth persists.
Read all positive factors

Cue Biopharma (CUE) vs. SPDR S&P 500 ETF (SPY)

Cue Biopharma Business Overview & Revenue Model

Company Description
Cue Biopharma, Inc. is a clinical-stage biopharmaceutical enterprise focused on creating biological therapies. Its central objective is the precise manipulation of the human immune system to address a spectrum of severe conditions, such as various...
How the Company Makes Money
Cue Biopharma does not have publicly established, recurring product sales from approved therapies; its revenue has primarily been generated through collaboration-related arrangements and other sources typical of clinical-stage biotech companies. K...

Cue Biopharma Financial Statement Overview

Summary
Revenue is improving (+19.2% TTM) and gross margin is strong (~72.6%), but the business remains deeply unprofitable (TTM net margin ~-59.6%) with significant ongoing cash burn (TTM FCF about -$24.6M). Leverage is modest (debt-to-equity ~0.16), yet declining equity/assets and sharply negative ROE (~-1.65) keep overall fundamentals weak.
Income Statement
34
Negative
Balance Sheet
56
Neutral
Cash Flow
28
Negative
BreakdownTTMDec 2025Mar 2025Mar 2024Dec 2022Dec 2021
Income Statement
Total Revenue37.65M27.47M9.29M5.49M1.25M14.94M
Gross Profit37.54M27.47M9.29M-32.61M1.25M16.72M
EBITDA-95.89M-22.27M-37.53M-46.05M-50.49M-45.44M
Net Income-164.11M-26.60M-40.67M-50.73M-53.01M-44.16M
Balance Sheet
Total Assets30.71M42.21M32.19M61.53M91.28M83.40M
Cash, Cash Equivalents and Short-Term Investments17.39M27.14M23.39M48.51M76.29M64.37M
Total Debt3.08M4.20M8.88M14.70M19.32M12.02M
Total Liabilities28.40M15.78M14.69M24.45M25.60M17.91M
Stockholders Equity2.31M26.43M17.50M37.09M65.68M65.49M
Cash Flow
Free Cash Flow-50.17M-21.86M-36.40M-39.96M-41.98M-39.75M
Operating Cash Flow-50.05M-21.69M-36.33M-39.96M-41.81M-38.84M
Investing Cash Flow131.00K75.00K32.00K25.00M-24.61M9.11M
Financing Cash Flow39.82M26.29M10.24M11.86M53.66M19.23M

Cue Biopharma Technical Analysis

Technical Analysis Sentiment
Positive
Last Price32.12
Price Trends
50DMA
29.53
Positive
100DMA
24.23
Positive
200DMA
18.37
Positive
Market Momentum
MACD
0.15
Negative
RSI
61.86
Neutral
STOCH
89.64
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CUE, the sentiment is Positive. The current price of 32.12 is above the 20-day moving average (MA) of 29.81, above the 50-day MA of 29.53, and above the 200-day MA of 18.37, indicating a bullish trend. The MACD of 0.15 indicates Negative momentum. The RSI at 61.86 is Neutral, neither overbought nor oversold. The STOCH value of 89.64 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CUE.

Cue Biopharma Risk Analysis

Cue Biopharma disclosed 66 risk factors in its most recent earnings report. Cue Biopharma reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Cue Biopharma Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$233.46M-1.27-1032.19%354.37%-63.33%
44
Neutral
$43.03M-0.94-160.72%893.01%41.74%
44
Neutral
$85.16M-2.21-284.80%-7.28%
42
Neutral
$20.14M-0.19411.46%-51.03%-35.20%
42
Neutral
$83.56M-1.04-70.14%16.04%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CUE
Cue Biopharma
34.20
9.64
39.23%
CELU
Celularity
0.70
-3.46
-83.25%
ALGS
Aligos Therapeutics
6.89
-1.88
-21.44%
GNTA
Genenta Science SpA Sponsored ADR
1.30
-2.28
-63.69%
MAIA
MAIA Biotechnology, Inc.
1.40
-0.18
-11.39%
ACRV
Acrivon Therapeutics, Inc.
1.95
0.56
40.29%

Cue Biopharma Corporate Events

Business Operations and StrategyExecutive/Board Changes
Cue Biopharma Appoints Veteran James Ahlers as CFO
Positive
Aug 3, 2026
Cue Biopharma, Inc. announced on August 3, 2026, that its board appointed veteran life sciences finance executive James Ahlers as chief financial officer and principal financial officer, effective July 30, 2026, underscoring the company’s fo...
Business Operations and StrategyPrivate Placements and Financing
Cue Biopharma Announces $50 Million Private Placement
Positive
Jul 10, 2026
On July 9, 2026, Cue Biopharma entered into a securities purchase agreement with accredited investors, including Cormorant Asset Management and Columbia Threadneedle Investments, to raise approximately $50 million through a private placement of co...
Business Operations and StrategyPrivate Placements and FinancingShareholder Meetings
Cue Biopharma Shareholders Approve 2026 Stock Incentive Plan
Positive
Jun 3, 2026
At a special meeting of stockholders held on June 1, 2026, Cue Biopharma shareholders approved the company’s 2026 Stock Incentive Plan, formalizing a new equity-based compensation framework previously adopted by the board. The plan’s a...
Business Operations and StrategyExecutive/Board Changes
Cue Biopharma Streamlines Governance and Strengthens Leadership Team
Positive
Jun 2, 2026
On May 29, 2026, Cue Biopharma announced that directors Jill Broadfoot, Peter Kiener, Frank Morich and Patrick Verheyen resigned from its board and board committees by mutual agreement, with the company emphasizing there were no disagreements rela...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 04, 2026