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Crinetics Pharma (CRNX)
:CRNX
Atumelnant
Healthy Volunteers
Phase I
Recruiting
A Study to Assess Pharmacokinetics, Safety, and Tolerability of Atumelnant in Healthy Japanese and Caucasian Participants
Oct 22, 2025
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Atumelnant
Congenital Adrenal Hyperplasia, Classic Congenital Adrenal Hyperplasia
Phase II/III
Not Yet Recruiting
A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)
Aug 29, 2025
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Atumelnant
Congenital Adrenal Hyperplasia, Classic Congenital Adrenal Hyperplasia
Phase III
Not Yet Recruiting
A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia
Aug 20, 2025
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Paltusotine
Carcinoid Syndrome, Carcinoid, Carcinoid Tumor, Carcinoid Tumor Of Ileum, Carcinoid Tumor Of Cecum, Carcinoid Tumor Of Liver, Carcinoid Tumor Of Pancreas, Carcinoid Syndrome Diarrhea, Carcinoid Intestine Tumor
Phase III
Recruiting
Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen
Jul 09, 2025
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Crn09682
Neuroendocrine Tumors, Sst2-Positive Neuroendocrine Neoplasms, Neuroendocrine Neoplasm
Phase I/II
Not Yet Recruiting
A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors
Jul 01, 2025
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Atumelnant (Crn04894)
Congenital Adrenal Hyperplasia, Classic Congenital Adrenal Hyperplasia
Phase II
Recruiting
An Extension Study to Evaluate Safety and Efficacy in Participants Treated With CRN04894
Nov 27, 2024
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Atumelnant (Crn04894)
Congenital Adrenal Hyperplasia, Classic Congenital Adrenal Hyperplasia
Phase II
Completed
Evaluate the Safety, Efficacy, and Pharmacokinetics of CRN04894 in Participants With Congenital Adrenal Hyperplasia (TouCAHn)
Jun 08, 2023
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Atumelnant
Cushing Syndrome, Cushing Disease, Ectopic Acth Syndrome
Phase I/II
Recruiting
A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome
Mar 27, 2023
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Paltusotine
Acromegaly
Phase III
Active Not Recruiting
A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (PATHFNDR-2)
Jan 05, 2022
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Paltusotine
Acromegaly
Phase III
Active Not Recruiting
A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly
Apr 06, 2021
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Crinetics Pharma (CRNX) have in its pipeline
CRNX is currently developing the following drugs: Atumelnant, Atumelnant, Atumelnant. These drug candidates are in various stages of clinical development as the company works toward FDA approval.