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Cellectar Biosciences (CLRB)
NASDAQ:CLRB
Clr 131
High-Grade Glioma
Phase I
Active Not Recruiting
Novel Targeted Radiotherapy in Pediatric Patients With Inoperable Relapsed or Refractory HGG
Oct 28, 2022
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Clr 131
Osteosarcoma, Neuroblastoma, Rhabdomyosarcoma, Pediatric Solid Tumor, Ewing Sarcoma, Dipg, Pediatric Lymphoma, Pediatric Brain Tumor
Phase I
Active Not Recruiting
Dose Escalation Study of CLR 131 in Children, Adolescents, and Young Adults With Relapsed or Refractory Malignant Tumors Including But Not Limited to Neuroblastoma, Rhabdomyosarcoma, Ewings Sarcoma, and Osteosarcoma
Mar 20, 2018
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Iopofosine I 131 Single Dose, Iopofosine I 131 Multiple Dose, Iopofosine I 131 Fractionated Dose
Multiple Myeloma, Marginal Zone Lymphoma, Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Diffuse Large B Cell Lymphoma, Mantle Cell Lymphoma, Lymphoplasmacytic Lymphoma, Waldenstrom Macroglobulinemia, Central Nervous System Lymphoma
Phase II
Active Not Recruiting
Study of Iopofosine I 131 (CLR 131) in Select B-Cell Malignancies (CLOVER-1) and Pivotal Expansion in Waldenstrom Macroglobulinemia
Oct 28, 2016
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Dexamethasone, I-131-Clr1404
Multiple Myeloma
Phase I
Completed
Dose Escalation Study of I-131-CLR1404 in Patients With Relapsed or Refractory Multiple Myeloma
Oct 22, 2014
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I-124-Clr1404
Glioblastoma
Phase II
Terminated
Imaging Trial With I-124-CLR1404 in Patients With Newly Diagnosed or Recurrent Glioblastoma
Jul 08, 2013
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Nov-205
Hepatitis C
Phase II
Completed
A Trial of NOV-205 in Hepatitis C Patients Who Failed Standard Therapy
Jan 26, 2010
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Carboplatin, Paclitaxel, Nov-002
Non Small Cell Lung Cancer
Phase III
Completed
Study of NOV-002 in Combination With Chemotherapy to Treat Lung Cancer
Jun 29, 2006
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Cellectar Biosciences (CLRB) have in its pipeline
CLRB is currently developing the following drugs: Clr 131, Clr 131, Iopofosine I 131 Single Dose, Iopofosine I 131 Multiple Dose, Iopofosine I 131 Fractionated Dose. These drug candidates are in various stages of clinical development as the company works toward FDA approval.