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Incyte (ICY) Drug Pipeline

Drug pipeline
Drug NameConditionStageStatusStudy NameTrial Start DateArticle
Inca033989, Best Available TreatmentEssential ThrombocythemiaPhase IIIRecruitingA Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential ThrombocythemiaMay 29, 2026―
Ruxolitinib, Povorcitinib, Incb054707Healthy ParticipantsPhase IRecruitingA Study to Evaluate Dermal Open-Flow Microperfusion and Plasma Pharmacokinetic Study of Multiple Doses of Oral Povorcitinib or Topical Ruxolitinib Cream in Healthy Adult ParticipantsMay 08, 2026
Incb161734, Investigator's Choice Of Chemotherapy, Mfolfirinox, GemnabpSolid TumorsPhase IIIRecruitingA Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal AdenocarcinomaApr 03, 2026
Inca033989Healthy ParticipantsPhase IRecruitingA Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of INCA033989 Following Subcutaneous or Intravenous Administration in Healthy Adult ParticipantsFeb 26, 2026
Standard Disease-Directed Therapy, Inca036978Myeloproliferative NeoplasmsPhase IRecruitingStudy of INCA036978 in Participants With Myeloproliferative NeoplasmsFeb 13, 2026
Bevacizumab, Folfox, Inca33890Crc (Colorectal Cancer)Phase IIIRecruitingA Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal CancerDec 09, 2025
Incb123667Healthy ParticipantsPhase ICompletedStudy Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]-INCB123667 in Healthy Male ParticipantsOct 16, 2025
PovorcitinibHidradenitis Suppurativa (Hs)Phase IIRecruitingPharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis SuppurativaOct 07, 2025
Incb123667, Investigator's Choice Of ChemotherapyOvarian CancerPhase IIIRecruitingStudy to Evaluate INCB123667 Versus Investigator's Choice of Chemotherapy in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 OverexpressionOct 06, 2025
Inca036873Solid Tumors, Hematologic MalignanciesPhase IRecruitingA Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological MalignanciesSep 19, 2025

FAQ

What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases: a. Preclinical testing b. Phase 1 – Safety and dosage c. Phase 2 – Effectiveness and side effects d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Incyte (CH:ICY) have in its pipeline
Incyte CH:ICY is currently developing the following drugs: Inca033989, Best Available Treatment, Ruxolitinib, Povorcitinib, Incb054707, Incb161734, Investigator's Choice Of Chemotherapy, Mfolfirinox, Gemnabp, Inca033989, Standard Disease-Directed Therapy, Inca036978, Bevacizumab, Folfox, Inca33890, Incb123667, Povorcitinib, Incb123667, Investigator's Choice Of Chemotherapy, Inca036873, Inca034176, Best Available Treatment, Inca000585, Ruxolitinib Cream, Incb000631, Itraconazole, Famotidine, Esomeprazole, Rifampin, Incb161734, Inca035784, Vehicle Cream, Ruxolitinib Cream, Incb057643, Retifanlimab, Incb177054, Inca034176, Best Available Therapy, Inca034176, Cetuximab, Mfolfirinox, Incb186748, Gemnabp, Vehicle Cream, Ruxolitinib, Axatilimab, Cyclophosphamide, Methotrexate, Mycophenolate Mofetil, Tacrolimus, Ruxolitinib, Corticosteroids, Inca034176, Ruxolitinib Ir, Ruxolitinib Xr, Tafasitamab, Rosuvastatin, Metformin, Digoxin, Probenecid, Povorcitinib, Corticosteroids, Ruxolitinib, Axatilimab, Incb160058. These drug candidates are in various stages of clinical development as the company works toward FDA approval.