Gross Margin CompressionSustained margin pressure from inflation, shipping costs, tariffs and FX can permanently depress unit economics on consumables and impair operating leverage. If low‑fifties gross margins persist, it will take larger volume gains or price recovery to translate revenue growth into durable profitability.
Still Negative Free Cash Flow And GAAP LossesAlthough cash generation has improved, recent FCF turned slightly negative and GAAP losses persist. Continued reliance on cash to build inventory or fund commercialization limits ability to self‑fund growth and increases sensitivity to financing markets until sustained positive FCF is achieved.
Geographic Revenue ConcentrationHeavy dependence on North American demand concentrates commercial risk (reimbursement, group purchasing, regional logistics). While NA growth is strong, limited geographic diversification exposes Cerus to policy, supply chain or payer changes that could disproportionately impact revenues.