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Barinthus Biotherapeutics (BRNS)
NASDAQ:BRNS
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Barinthus Biotherapeutics (BRNS) AI Stock Analysis

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BRNS

Barinthus Biotherapeutics

(NASDAQ:BRNS)

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Neutral 44 (OpenAI - Gpt-5.6Sol)
Rating:44Neutral
Price Target:
$0.64
▼(-3.03% Downside)
Action:Reiterated
Date:08/06/26
The score is primarily held down by weak financial performance (zero TTM revenue, large ongoing losses, and sustained cash burn) and bearish technicals (price below key moving averages with negative MACD). Corporate events are mixed—transaction progress is constructive, but Nasdaq compliance/listing pressure is a meaningful risk—while valuation is constrained by negative earnings and no dividend support.
Positive Factors
Low financial leverage
Low debt relative to equity limits interest and refinancing pressure, giving Barinthus more flexibility to fund clinical programs and pursue strategic options while operating as a development-stage biotechnology company.
Negative Factors
No current commercial revenue
The absence of recurring product revenue leaves the company dependent on clinical execution, partnerships, and external financing, making earnings visibility weak until a candidate is successfully commercialized.
Read all positive and negative factors
Positive Factors
Negative Factors
Low financial leverage
Low debt relative to equity limits interest and refinancing pressure, giving Barinthus more flexibility to fund clinical programs and pursue strategic options while operating as a development-stage biotechnology company.
Read all positive factors

Barinthus Biotherapeutics (BRNS) vs. SPDR S&P 500 ETF (SPY)

Barinthus Biotherapeutics Business Overview & Revenue Model

Company Description
Barinthus Biotherapeutics PLC is a clinical-stage biopharmaceutical company focused on developing novel immunotherapeutic drug candidates for treating autoimmune and inflammatory diseases. The company is prioritizing the development of its proprie...
How the Company Makes Money
Barinthus Biotherapeutics primarily makes money through a combination of: (1) collaboration, licensing, and partnership-related revenue (such as upfront payments, research funding, and potential development/regulatory/sales milestone payments), wh...

Barinthus Biotherapeutics Financial Statement Overview

Summary
Development-stage profile with weak fundamentals: revenue is $0 in TTM/2025 after a one-year spike in 2024, while losses remain large (TTM net loss ~$41.7M; 2025 net loss ~$66.6M). Cash flow is consistently negative (TTM FCF about -$26.4M; 2025 about -$48.0M), implying ongoing funding needs. Balance sheet leverage is relatively low (TTM debt-to-equity ~0.17), but equity has fallen sharply over time, reflecting sustained burn/dilution risk.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
24
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.0014.97M802.00K44.70M268.00K
Gross Profit-1.76M-5.86M14.97M802.00K44.70M268.00K
EBITDA-37.52M-62.90M-55.37M-71.06M5.19M-47.87M
Net Income-41.74M-66.58M-61.07M-73.35M5.34M-50.87M
Balance Sheet
Total Assets81.89M98.17M160.33M214.51M270.20M280.71M
Cash, Cash Equivalents and Short-Term Investments59.30M70.46M110.66M142.09M194.38M214.05M
Total Debt10.29M11.28M12.01M12.98M8.77M7.22M
Total Liabilities24.76M23.88M30.19M27.51M27.00M28.15M
Stockholders Equity57.07M74.21M130.03M186.78M242.90M252.13M
Cash Flow
Free Cash Flow-26.43M-48.02M-29.83M-56.34M-20.57M-33.73M
Operating Cash Flow-26.43M-47.98M-28.94M-50.92M-14.43M-32.58M
Investing Cash Flow569.00K416.00K-892.00K-5.41M-5.75M-12.91M
Financing Cash Flow0.002.00K2.16M1.87M325.00K222.74M

Barinthus Biotherapeutics Risk Analysis

Barinthus Biotherapeutics disclosed 108 risk factors in its most recent earnings report. Barinthus Biotherapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Barinthus Biotherapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$46.65M-1.03-160.72%893.01%41.74%
49
Neutral
$276.55M-1.75-90.30%48.20%
48
Neutral
$66.88M-1.02-70.89%1.11%
44
Neutral
$26.96M-0.69-63.87%-100.00%41.21%
44
Neutral
$11.06M-3.13-70.74%373.88%-59.79%
40
Underperform
$5.48M-0.30-160.28%-84.26%14.73%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BRNS
Barinthus Biotherapeutics
0.71
-0.47
-40.12%
CLGN
Collplant Holdings
0.31
-2.46
-88.92%
ALXO
ALX Oncology Holdings
1.98
0.84
73.68%
ALGS
Aligos Therapeutics
7.51
-3.55
-32.10%
GDTC
CytoMed Therapeutics Limited
1.00
-1.00
-50.20%
BOLD
Boundless Bio Inc.
2.92
1.78
155.70%

Barinthus Biotherapeutics Corporate Events

Business Operations and StrategyDelistings and Listing ChangesM&A Transactions
Barinthus Advances Clywedog Merger and Nasdaq Relisting Plans
Neutral
Aug 25, 2026
On August 24, 2026, Barinthus Biotherapeutics announced progress on its all-stock combination with Clywedog Therapeutics, including plans to delist its American Depositary Shares from Nasdaq and transfer the listing to a new parent company, Beacon...
Executive/Board ChangesDelistings and Listing ChangesDividendsRegulatory Filings and ComplianceShareholder Meetings
Barinthus Biotherapeutics Holds 2026 Annual General Meeting
Negative
Jul 2, 2026
Barinthus Biotherapeutics held its 2026 Annual General Meeting on July 2, 2026, where shareholders approved all resolutions, including the re-election of directors Karen T. Dawes and Anne M. Phillips and the reappointment and remuneration authoriz...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 06, 2026