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BioNTech SE (BNTX) Q2 2026 Earnings Report
BNTX Q2 2026 EPS Results
- Actual EPS
- -$3.63
- Consensus EPS
- -$2.35
- Beat/Miss
- Missed by -$1.28
- One Year Ago EPS
- -$1.79
BNTX Q2 2026 Revenue Results
- Actual Revenue
- $122.78M
- Expected Revenue
- $176.79M
- Beat/Miss
- Missed by -$54.01M
- YoY Revenue Growth
- -58.46%
Earnings Announcement Details
- Quarter
- Q2 2026
- Date
- 08/04/2026
- Time
- Before Open
- Conference Call
- Tuesday, August 4, 2026
BioNTech SE's next earnings date is estimated for November 3, 2026, based on past reporting schedules.
Q2 2026 Earnings Call Audio
Q2 2026 Earnings Slide Deck
Q2 2026 Earnings Call Summary
The call balances meaningful near‑term financial headwinds (sharp Q2 revenue decline, guidance reduction, increased SG&A and some timeline pushes) against substantial clinical and strategic progress: multiple encouraging Phase II signals (pumitamig, gotistobart), initiation of a Phase III for LCD, continued advancement of mRNA oncology programs, a strong cash position (EUR 16.6B) and active capital return. The pipeline momentum and capital strength mitigate short‑term revenue weakness, but the quarter highlights both execution progress and clear near‑term commercial challenges.
BioNTech revised its full‑year 2026 guidance to revenues of EUR 1.6–1.9 billion, adjusted R&D expenses of EUR 2.0–2.3 billion and adjusted SG&A unchanged at EUR 700–800 million. In Q2 the company reported revenues of EUR 106 million (vs. EUR 261 million a year ago) and H1 revenues of EUR 224 million; Q2 adjusted R&D was EUR 477 million (vs. EUR 509 million) and H1 adjusted R&D was EUR 1,004 million; Q2 adjusted SG&A was EUR 198 million (vs. EUR 137 million) and H1 adjusted SG&A was EUR 349 million. BioNTech ended the quarter with EUR 16.6 billion in cash, cash equivalents and securities (vs. EUR 16.0 billion a year earlier), is executing an up to $1 billion share repurchase program (USD 152 million repurchased so far), expects to recognize a EUR 613 million BMS collaboration payment largely in Q3, and cited a roughly EUR 400 million midpoint guidance reduction driven ~80% by softer COVID vaccine demand (with the remainder from milestone timing and other event‑driven items); near‑term results also reflect impairments and restructuring costs related to manufacturing footprint consolidation.
- Promising pumitamig Phase II Global DataPumitamig (PD-L1/VEGF bispecific) showed robust activity in a global Phase II cohort (40 evaluable patients): unconfirmed ORR 72.5% and confirmed ORR 62.5%. Notable subgroup efficacy: PD-L1 TPS <1% (≈58% of cohort) confirmed ORR 47.6%; TPS 1–49% 77.8%; TPS ≥50% 100% (6/6). Data consistent across China and global cohorts in multiple tumor types (SCLC, NSCLC, TNBC), supporting ongoing pivotal Phase III programs.
- Gotistobart Demonstrates Durable Benefit in IO-Pretreated NSCLCGotistobart (selective TREG-depleting anti–CTLA-4) from non‑pivotal Stage 1 of PRESERVE-003 showed a 12‑month PFS rate of 25% vs 0% for docetaxel, a 54% reduction in risk of death (HR 0.46), median OS not yet reached vs ~10 months for docetaxel, and 12‑month OS of 63% vs 30%. Pivotal-stage interim analysis expected toward end of 2026.
- LCD (B7-H3 ADC) Advances to Phase III in mCRPCLCD (elfetabart drozuntecan, BNT324) dosed first patient in a Phase III trial vs docetaxel for taxane‑naive metastatic castration‑resistant prostate cancer. Over 1,000 patients treated to date across >10 tumor types (including ~400 patients in combination with pumitamig), with favorable safety profile supporting registrational development.
- Progress Across mRNA Cancer Immunotherapy PortfolioKey programs advanced: autogene cevumeran randomized adjuvant colorectal cancer Phase II enrollment complete and DSMB recommended continuing blinded; final readout expected 2027. BNT113 (HPV16 FixVac) Phase II/III interim PFS analysis expected in 2026. T‑PAM is in two pivotal trials (endometrial and HER2‑low HR+ breast); primary breast analysis expected Q4 2026.
- Strong Balance Sheet and Capital ReturnsCash, cash equivalents and investments of EUR 16.6 billion at quarter end vs EUR 16.0 billion a year earlier (+EUR 0.6 billion, +3.8% YoY). Share repurchase program execution: $152 million repurchased to date against an up-to-$1 billion authorization (~15.2% executed).
- R&D Prioritization and Cost DisciplineAdjusted R&D expenses in Q2 decreased to EUR 477 million from EUR 509 million YoY (−6.3%), reflecting portfolio prioritization and favorable cost-sharing with partners while maintaining investment in prioritized oncology and ADC programs.
BNTX Earnings History
| Report Date | Fiscal Quarter | Forecast / EPS | Last Year's EPS | EPS YoY Change | Press Release |
|---|---|---|---|---|---|
| Nov 03, 2026 | 2026 (Q3) | 0.75- | -0.13 | ― | ― |
| Aug 04, 2026 | 2026 (Q2) | -2.35-3.63 | -1.79 | -102.50% (-1.84) | |
| May 05, 2026 | 2026 (Q1) | -2.46-2.35 | -1.94 | -21.39% (-0.41) | |
| Mar 10, 2026 | 2025 (Q4) | -0.18-1.40 | 1.21 | -215.74% (-2.61) | |
| Nov 03, 2025 | 2025 (Q3) | -1.07-0.13 | 0.91 | -114.81% (-1.04) | |
| Aug 04, 2025 | 2025 (Q2) | -2.56-1.79 | -3.77 | 52.38% (+1.97) | |
| May 05, 2025 | 2025 (Q1) | -2.57-1.94 | -1.47 | -32.06% (-0.47) | |
| Mar 10, 2025 | 2024 (Q4) | 0.501.21 | 2.13 | -43.16% (-0.92) | |
| Nov 04, 2024 | 2024 (Q3) | -1.750.91 | 0.75 | 20.90% (+0.16) | |
| Aug 05, 2024 | 2024 (Q2) | -2.29-3.77 | -0.89 | -325.32% (-2.88) |
The table shows recent earnings report dates and whether the forecast was beat or missed. See the change in forecast and EPS from the previous year.
