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Immutep Ltd (AU:IMM)
ASX:IMM
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Immutep Ltd (IMM) AI Stock Analysis

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AU:IMM

Immutep Ltd

(Sydney:IMM)

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Neutral 41 (OpenAI - 4o)
Rating:41Neutral
Price Target:
AU$0.00
▼(-100.00% Downside)
Immutep Ltd's overall stock score is primarily impacted by its financial performance, which is hindered by persistent losses and negative cash flows. Technical analysis indicates a bearish trend, and valuation metrics are unattractive due to the lack of profitability. The absence of earnings call data and corporate events means these factors do not influence the score.

Immutep Ltd (IMM) vs. iShares MSCI Australia ETF (EWA)

Immutep Ltd Business Overview & Revenue Model

Company DescriptionImmutep Limited, a biotechnology company, engages in the research and development of pharmaceutical products. The company develops immunotherapeutic products for the treatment of cancer and autoimmune diseases. Its lead product candidate is eftilagimod alpha (efti or IMP321), a recombinant protein that is in Phase IIb clinical trial as a chemo-immunotherapy combination for metastatic breast cancer. The company also develops TACTI-002, which is in a Phase II clinical trial for the treatment of head and neck squamous cell carcinoma (HNSCC) and non-small cell lung cancer; TACTI-003 that is in Phase IIb clinical trial to treat HNSCC; and INSIGHT-003, which is in a Phase I clinical trial for the treatment of solid tumors, as well as INSIGHT-005 that is in Phase I/IIa clinical trial to treat solid tumors. In addition, it offers IMP761, an agonist of lymphocyte activation gene 3 for autoimmune disease; IMP701, an antagonist antibody that acts to stimulate T cell proliferation in cancer patients; and IMP731, a depleting antibody that removes T cells involved in autoimmunity. Immutep Limited has collaboration agreements with GlaxoSmithKline, Novartis, CYTLIMIC Inc., Merck & Co., Inc., Institute of Clinical Cancer Research, Merck KGaA, and EOC Pharma. The company was formerly known as Prima BioMed Ltd and changed its name to Immutep Limited in November 2017. Immutep Limited was incorporated in 1987 and is headquartered in Sydney, Australia.
How the Company Makes MoneyImmutep generates revenue primarily through a combination of collaborations, partnerships, and potential product sales. The company engages in strategic collaborations with larger pharmaceutical companies that often include upfront payments, milestone payments based on development progress, and royalties on future sales of products developed through these partnerships. Additionally, Immutep may receive funding through government grants and research initiatives aimed at advancing their clinical programs. Their focus on clinical trials and research grants allows them to explore new therapeutic avenues and expand their product pipeline, which can lead to future monetization through licensing agreements or direct sales once therapies are approved.

Immutep Ltd Financial Statement Overview

Summary
Immutep Ltd faces significant financial challenges with persistent losses and negative cash flows. Despite a strong equity position and low leverage, the company's inability to generate profits and positive cash flows is concerning. Improvements in operational efficiency and revenue generation are needed for financial stability.
Income Statement
35
Negative
Immutep Ltd has shown modest revenue growth, but the company is struggling with negative margins across the board. The gross profit margin and net profit margin are both negative, indicating that the company is not currently profitable. The EBIT and EBITDA margins are also negative, suggesting operational inefficiencies. Overall, the income statement reflects significant challenges in achieving profitability.
Balance Sheet
50
Neutral
The balance sheet shows a low debt-to-equity ratio, indicating conservative leverage and a strong equity position. However, the return on equity is negative, reflecting ongoing losses. The equity ratio is relatively healthy, suggesting a stable capital structure, but the company's inability to generate positive returns remains a concern.
Cash Flow
40
Negative
The cash flow statement highlights significant negative operating and free cash flows, although there is a notable improvement in free cash flow growth. The operating cash flow to net income ratio is negative, indicating cash flow challenges. The free cash flow to net income ratio is slightly above 1, suggesting that cash flow is somewhat aligned with net income, but overall cash flow performance is weak.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue5.04M5.04M3.84M3.51M170.37K3.86M
Gross Profit-56.37M-56.37M-37.70M1.44M-1.89M1.79M
EBITDA-62.88M-62.88M-44.54M-42.88M-31.87M-20.72M
Net Income-61.43M-61.43M-42.72M-39.90M-32.21M-29.90M
Balance Sheet
Total Assets156.98M156.98M201.58M147.45M102.17M82.03M
Cash, Cash Equivalents and Short-Term Investments129.69M129.69M181.88M123.42M80.00M60.13M
Total Debt1.63M1.63M1.59M1.23M1.73M2.82M
Total Liabilities13.35M13.35M12.06M10.98M8.09M8.76M
Stockholders Equity143.64M143.64M189.52M136.47M94.08M73.27M
Cash Flow
Free Cash Flow-62.10M-62.10M-35.75M-35.93M-30.25M-17.66M
Operating Cash Flow-62.05M-62.05M-34.82M-35.88M-30.23M-17.64M
Investing Cash Flow-38.53M-38.53M-21.02M-31.00K-22.91K-15.60K
Financing Cash Flow-525.12K-525.12K95.18M76.04M50.33M52.68M

Immutep Ltd Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.26
Price Trends
50DMA
0.27
Negative
100DMA
0.26
Negative
200DMA
0.27
Negative
Market Momentum
MACD
>-0.01
Positive
RSI
37.85
Neutral
STOCH
6.67
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AU:IMM, the sentiment is Negative. The current price of 0.26 is below the 20-day moving average (MA) of 0.29, below the 50-day MA of 0.27, and below the 200-day MA of 0.27, indicating a bearish trend. The MACD of >-0.01 indicates Positive momentum. The RSI at 37.85 is Neutral, neither overbought nor oversold. The STOCH value of 6.67 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AU:IMM.

Immutep Ltd Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
AU$541.41M-27.89%67.26%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
AU$294.19M-20.59-83.97%1271.12%36.87%
41
Neutral
$375.34M-35.86%-19.21%
41
Neutral
AU$97.88M-42.68%63.46%
41
Neutral
$96.17M-83.09%55.94%
40
Underperform
AU$106.68M-13.09-47.98%700.00%26.88%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:IMM
Immutep Ltd
0.26
-0.05
-17.74%
AU:IMU
Imugene
0.33
-1.31
-80.09%
AU:ATH
Alterity Therapeutics
0.01
0.00
0.00%
AU:DXB
Dimerix Limited
0.48
0.09
23.08%
AU:RAC
Race Oncology Ltd.
3.32
1.80
118.42%
AU:ALA
Arovella Therapeutics Limited
0.09
-0.10
-53.16%

Immutep Ltd Corporate Events

Immutep Secures A$4.6 Million R&D Tax Incentive from French Government
Nov 3, 2025

Immutep Limited has received a €2,588,954 (~ A$4,567,769) R&D tax incentive payment from the French Government under the Crédit d’Impôt Recherche scheme. This funding will support the global clinical development of eftilagimod alfa and IMP761, enhancing Immutep’s operations and potentially strengthening its position in the biotechnology industry.

The most recent analyst rating on (AU:IMM) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Immutep Limited Announces 2025 AGM with Key Resolutions
Oct 23, 2025

Immutep Limited has announced its 2025 Annual General Meeting (AGM) scheduled for November 27, 2025, in Sydney, with provisions for a live webcast for those unable to attend in person. The AGM will address the company’s financial statements and include a resolution on the adoption of the Remuneration Report, which is advisory and non-binding, reflecting the company’s commitment to transparency and shareholder engagement.

The most recent analyst rating on (AU:IMM) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Immutep Limited Releases 2025 Corporate Governance Statement
Oct 23, 2025

Immutep Limited has released its corporate governance statement for the financial year ending 30 June 2025, which is available on their website. The statement, approved by the board, outlines the company’s adherence to the ASX Corporate Governance Council’s principles and recommendations, highlighting its commitment to transparency and accountability in its operations. This disclosure is crucial for stakeholders as it ensures compliance with governance standards, potentially impacting the company’s reputation and investor confidence.

The most recent analyst rating on (AU:IMM) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Immutep Ltd Releases 2025 Annual Report Highlighting Strategic Developments
Oct 23, 2025

Immutep Ltd has released its annual report for the year ending June 30, 2025, detailing its financial performance and strategic developments. The report highlights the company’s ongoing commitment to advancing its immunotherapy pipeline, which could significantly impact its market position and offer potential benefits to stakeholders in the biotechnology sector.

The most recent analyst rating on (AU:IMM) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Immutep’s Efti Shows Promising Results in Lung Cancer Treatment
Oct 19, 2025

Immutep Limited has announced promising results from its INSIGHT-003 trial, presented at the ESMO Congress 2025, showcasing a novel combination of eftilagimod alfa (efti) with KEYTRUDA and chemotherapy. This combination has demonstrated strong objective response rates and disease control rates in first-line non-small cell lung cancer (1L NSCLC) patients across all PD-L1 expression levels, particularly benefiting those with low and no PD-L1 expression. The trial results suggest that efti could significantly alter the treatment landscape for 1L NSCLC, providing a new standard of care and addressing the high unmet need in patients with PD-L1 expression under 50%.

The most recent analyst rating on (AU:IMM) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Immutep’s Efti Shows Promising Results in Soft Tissue Sarcoma Trial
Oct 19, 2025

Immutep Limited announced positive results from its EFTISARC-NEO Phase II trial, which evaluated the novel combination of eftilagimod alfa (efti) with radiotherapy and KEYTRUDA® in treating resectable soft tissue sarcoma (STS). The trial met its primary endpoint, achieving a 51.5% tumor hyalinization/fibrosis rate, significantly surpassing the historical 15% rate from standard radiotherapy alone. This outcome suggests potential improvements in overall and recurrence-free survival for STS patients, addressing a critical unmet medical need. The findings, presented at the ESMO Congress 2025, highlight the promising efficacy and safety profile of efti, potentially paving the way for new therapeutic options in STS treatment.

The most recent analyst rating on (AU:IMM) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Immutep Completes FDA Project Optimus, Advances Cancer Immunotherapy
Oct 12, 2025

Immutep Limited has successfully completed the FDA’s Project Optimus requirements, confirming 30 mg as the optimal biological dose for its immunotherapy candidate efti, which is significant for its oncology pipeline and future Biological License Applications. This development is strategically important for Immutep’s ongoing and future clinical trials, including the Phase III TACTI-004 trial for non-small cell lung cancer, positioning the company to advance its novel immunotherapy to market and address global cancer patient needs.

The most recent analyst rating on (AU:IMM) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Immutep Achieves Key Milestone in Phase III Lung Cancer Trial
Oct 8, 2025

Immutep Limited has announced a significant milestone in its TACTI-004 (KEYNOTE-F91) Phase III trial for treating advanced non-small cell lung cancer (NSCLC). The trial, which combines eftilagimod alfa with KEYTRUDA and chemotherapy, has enrolled over 170 patients, surpassing the number needed for futility analysis. With over 100 clinical sites activated across 24 countries, the trial is on track for a futility analysis in early 2026. This development could potentially transform the treatment landscape for NSCLC, a major cancer type with high unmet medical needs, by enhancing response rates and improving efficacy regardless of PD-L1 expression.

The most recent analyst rating on (AU:IMM) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Immutep Director Converts Performance Rights into Shares
Oct 8, 2025

Immutep Ltd announced a change in the director’s interest, where Mr. Pete Meyers converted 388,889 performance rights into fully paid ordinary shares. This change reflects the director’s compensation strategy, where he receives part of his fees in performance rights, aligning his interests with those of the shareholders.

The most recent analyst rating on (AU:IMM) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Immutep Ltd Announces Director’s Interest Change
Oct 8, 2025

Immutep Ltd has announced a change in the interest of its director, Dr. Frederic Triebel, involving the conversion of 900,000 performance rights into fully paid ordinary shares. This adjustment, which was previously approved by shareholders, reflects the company’s ongoing commitment to aligning executive incentives with shareholder interests, potentially impacting its market perception and stakeholder confidence.

The most recent analyst rating on (AU:IMM) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Immutep Ltd Announces Director’s Acquisition of Shares
Oct 8, 2025

Immutep Ltd announced a change in the director’s interest, with Mr. Marc Voigt acquiring 1,200,000 fully paid ordinary shares through the vesting and exercise of performance rights. This change reflects the company’s ongoing commitment to aligning executive interests with shareholder value, potentially impacting investor confidence and market perception positively.

The most recent analyst rating on (AU:IMM) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Immutep Ltd Issues New Shares on ASX
Oct 1, 2025

Immutep Ltd has announced the issuance of 4,055,555 fully paid ordinary shares, which will be quoted on the Australian Securities Exchange (ASX) starting October 1, 2025. This move is part of the company’s strategy to enhance its capital structure and potentially strengthen its market position, offering stakeholders an opportunity to invest in its growth and development.

The most recent analyst rating on (AU:IMM) stock is a Buy with a A$1.20 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Immutep Collaborates with GW Cancer Center on Efti Trial for Breast Cancer
Sep 21, 2025

Immutep Limited has announced a research collaboration with the George Washington University Cancer Center to initiate a Phase II trial evaluating eftilagimod alfa (efti) as a neoadjuvant therapy for early-stage HR+/HER2-negative breast cancer. The trial will explore efti’s potential to activate a broad anti-cancer immune response, potentially leading to high pathologic complete response rates and improved disease-free survival. This collaboration allows Immutep to expand its clinical pipeline cost-effectively and further positions efti as a promising immunotherapy in both metastatic and neoadjuvant cancer settings.

The most recent analyst rating on (AU:IMM) stock is a Buy with a A$1.20 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Immutep’s Phase II Trial Data on Soft Tissue Sarcoma to be Presented at CTOS 2025
Sep 8, 2025

Immutep Limited announced that data from its EFTISARC-NEO Phase II trial will be presented at the Connective Tissue Oncology Society (CTOS) 2025 Annual Meeting. This trial is the first to evaluate eftilagimod alpha in a neoadjuvant setting combined with radiotherapy and pembrolizumab for soft tissue sarcoma, an orphan disease with significant unmet medical needs. The trial, conducted in Poland and funded by the Polish government, could have implications for the treatment of soft tissue sarcoma, potentially improving outcomes in a field with poor prognosis.

The most recent analyst rating on (AU:IMM) stock is a Buy with a A$0.46 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Immutep Reports Increased Loss Amid Rising R&D Costs
Aug 29, 2025

Immutep Limited reported a significant increase in its loss after tax for the financial year ending June 30, 2025, primarily due to a $19.9 million rise in research and development and intellectual property expenses, largely attributed to clinical trial costs. Despite a rise in other income and interest income, the company’s net tangible asset backing per ordinary security decreased, and no dividends were declared, indicating financial challenges amidst ongoing investments in its core research activities.

The most recent analyst rating on (AU:IMM) stock is a Buy with a A$0.98 price target. To see the full list of analyst forecasts on Immutep Ltd stock, see the AU:IMM Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 07, 2025