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ARWR Stock Chart & Stats
$88.88
-$1.18(-1.36%)
At close: 4:00 PM EDT
$88.88
-$1.18(-1.36%)
Day’s Range― - ―
52-Week Range$36.57 - $95.49
Previous CloseN/A
Volume1.83M
Average Volume (3M)2.23M
Market Cap
$7.90B
Enterprise Value$11.46B
Total Cash (Recent Filing)$1.60B
Total Debt (Recent Filing)$864.07M
Price to Earnings (P/E)―
Beta2.51
Next Earnings
Nov 30, 2026EPS Estimate
-1.52Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-2.24
Shares Outstanding141,254,470
10 Day Avg. Volume2,140,931
30 Day Avg. Volume2,225,218
Financial Highlights & Ratios
PEG Ratio28.34
Price to Book (P/B)9.90
Price to Sales (P/S)5.56
P/FCF Ratio29.41
Enterprise Value/Market Cap1.45
Enterprise Value/Revenue17.12
Enterprise Value/Gross Profit17.12
Enterprise Value/Ebitda-85.75
Forecast
1Y Price Target
$109.00Price Target Upside22.64% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering13
EPS Forecast (FY)-4.86
Revenue Forecast (FY)$336.79M
Bulls Say, Bears Say
Bulls Say
Phase III EfficacyPivotal trials delivered deep and consistent triglyceride reductions while also reducing acute pancreatitis events, including a 100% reduction in the highest-risk subgroup. These results materially strengthen the clinical and commercial case for plozasiran over the next several quarters.
Regulatory And Commercial ProgressBroad approvals and improving prescription activity indicate that Arrowhead is progressing from development toward commercialization. Geographic reach, prescriber adoption, and an accelerated sNDA plan can support durable product uptake as payer and physician engagement expands.
Financial FlexibilityA substantial cash and investment position provides funding capacity for clinical development, regulatory submissions, commercialization, and strategic initiatives. This liquidity gives Arrowhead room to pursue its pipeline and absorb near-term investment needs while products mature.
Bears Say
Persistent Losses And High SpendingLarge and widening losses show that Arrowhead has not yet converted clinical progress into sustainable profitability. Elevated R&D and commercial spending may be strategically necessary, but continued cost growth increases execution pressure and can extend the path to positive earnings.
Uneven Cash Generation And LeverageNegative trailing cash flow and still-elevated leverage reduce financial flexibility despite improvement from earlier periods. If cash burn persists while the company remains unprofitable, Arrowhead may face greater funding demands and less room to absorb development or launch setbacks.
Early Commercial ScaleInitial prescription growth is encouraging, but product revenue remains too small to materially support the cost base. Management expects a gradual ramp requiring physician and payer education, so commercialization must scale substantially before it offsets ongoing development spending.
Arrowhead Pharmaceuticals News
ARWR FAQ
What was Arrowhead Pharmaceuticals’s price range in the past 12 months?
Arrowhead Pharmaceuticals lowest stock price was $36.57 and its highest was $95.49 in the past 12 months.
What is Arrowhead Pharmaceuticals’s market cap?
Arrowhead Pharmaceuticals’s market cap is $7.90B.
When is Arrowhead Pharmaceuticals’s upcoming earnings report date?
Arrowhead Pharmaceuticals’s upcoming earnings report date is Nov 30, 2026 which is in 42 days.
How were Arrowhead Pharmaceuticals’s earnings last quarter?
Arrowhead Pharmaceuticals released its earnings results on Aug 04, 2026. The company reported -$1.36 earnings per share for the quarter, missing the consensus estimate of -$1.277 by -$0.083.
Is Arrowhead Pharmaceuticals overvalued?
According to Wall Street analysts Arrowhead Pharmaceuticals’s price is currently Undervalued.
Does Arrowhead Pharmaceuticals pay dividends?
Arrowhead Pharmaceuticals does not currently pay dividends.
What is Arrowhead Pharmaceuticals’s EPS estimate?
Arrowhead Pharmaceuticals’s EPS estimate is -1.52.
How many shares outstanding does Arrowhead Pharmaceuticals have?
Arrowhead Pharmaceuticals has 141,254,470 shares outstanding.
What happened to Arrowhead Pharmaceuticals’s price movement after its last earnings report?
Arrowhead Pharmaceuticals reported an EPS of -$1.36 in its last earnings report, missing expectations of -$1.277. Following the earnings report the stock price went down -2.991%.
Which hedge fund is a major shareholder of Arrowhead Pharmaceuticals?
Currently, no hedge funds are holding shares in ARWR
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Arrowhead Pharmaceuticals Stock Smart Score
Neutral
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10
Analyst Consensus
Strong Buy
Average Price Target:
$109.00 (22.64% Upside)
$109.00 (22.64% Upside)
Blogger Sentiment
Bullish
ARWR Sentiment 78%
Sector Average 67%
Sector Average 67%
Hedge Fund Trend
Decreased
By 285.0K Shares
Last Quarter.
Last Quarter.
Insider Transactions
Sold Shares
Worth $1.2M over
the Last 3 Months
the Last 3 Months
Crowd Wisdom
Positive
Last 7 Days ▲ 0.5%
Last 30 Days ▲ 2.9%
Last 30 Days ▲ 2.9%
News Sentiment
Very Bullish
Bullish news 100%
Bearish news 0%
Bearish news 0%
Technicals
SMA
Negative
20 days / 200 days
Momentum
43.44%
12-Months-Change
Fundamentals
Return on Equity
-60.54%
Trailing 12-Months
Asset Growth
52.98%
Trailing 12-Months
Learn more about TipRanks Smart Score
Company Description
Arrowhead Pharmaceuticals
Arrowhead Pharmaceuticals, Inc., founded in 1989 and based in Pasadena, California, is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for complex and challenging-to-treat diseases within the United States. The company's extensive therapeutic pipeline primarily leverages RNA interference (RNAi) technology. Among its advanced clinical programs are: ARO-AAT, a Phase II therapeutic targeting liver diseases associated with alpha-1 antitrypsin deficiency; ARO-APOC3, which is undergoing both Phase 2b and Phase 3 clinical evaluations for hypertriglyceridemia; ARO-ANG3, currently in Phase 2b development to reduce the production of angiopoietin-like protein 3; and ARO-HIF2, a Phase 1b candidate designed to treat clear cell renal cell carcinoma. Arrowhead also has several compounds in earlier clinical development, including ARO-HSD in Phase 1/2a for other liver diseases, ARO-ENaC in Phase 1/2a, aimed at decreasing the epithelial sodium channel alpha subunit in lung airways, and ARO-C3, also in Phase 1/2a, for complement-mediated diseases. Further expanding its diverse portfolio, the company is actively developing ARO-Lung2 for chronic obstructive pulmonary disorder (COPD), ARO-DUX4 for facioscapulohumeral muscular dystrophy, ARO-XDH for uncontrolled gout, and ARO-COV for COVID-19 and other pulmonary-borne pathogens. Beyond its core internal programs, Arrowhead is involved in the progression of JNJ-3989, a subcutaneously administered RNAi therapeutic for chronic hepatitis B virus infection; Olpasiran, intended to reduce apolipoprotein A production; and ARO-AMG1, which targets genetically validated cardiovascular pathways. Strategic collaborations are integral to Arrowhead's development efforts. The company holds a licensing and research agreement with Janssen Pharmaceuticals, Inc. for the co-development of ARO-JNJ1, ARO-JNJ2, and ARO-JNJ3, all RNAi therapeutics focused on liver-expressed targets. Additionally, Arrowhead has a licensing and research partnership with Takeda Pharmaceuticals U.S.A., Inc. to develop an RNAi therapeutic candidate specifically for liver disease.
ARWR Earnings Call
Q3 2026
0:00 / 0:00
Earnings Call Sentiment|Positive
The call was decidedly positive on clinical and strategic fronts: landmark Phase III SHASTA-3/4 results (deep TG reductions and major reductions in acute pancreatitis), broad regulatory approvals, accelerating commercial traction in FCS, strong partnership revenue and a robust pipeline with multiple near-term data catalysts. Offsetting items include increased net losses and higher operating spend as Arrowhead scales R&D and commercial infrastructure, a sizable near-term cash payment for a priority review voucher ($215M), and the fact that commercial product revenues remain small today. Overall, management portrayed the financial investments as deliberate and tied to significant near-term derisking and value-creation events.View all ARWR earnings summariesARWR Stock 12 Month Forecast
Average Price Target
$109.00
▲(22.64% Upside)
Technical Analysis
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Ownership Overview
3.64% Insiders
19.68% Mutual Funds
0.64% Other Institutional Investors
50.58% Public Companies and
Individual Investors