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Lisata Therapeutics (LSTA)
NASDAQ:LSTA
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Lisata Therapeutics (LSTA) AI Stock Analysis

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LSTA

Lisata Therapeutics

(NASDAQ:LSTA)

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Neutral 43 (OpenAI - Gpt-5.6Sol)
Rating:43Neutral
Price Target:
$1.50
▼(-17.58% Downside)
Action:Reiterated
Date:08/25/26
The score is primarily dragged down by weak financial performance—minimal and declining revenue alongside large losses and persistent cash burn—partly offset by a debt-free balance sheet. Technicals remain broadly weak versus longer-term averages (despite some near-term stabilization), and valuation signals provide limited support due to a negative P/E and no dividend yield data.
Positive Factors
Proprietary Oncology Platform
CEND is designed to improve delivery of anti-cancer agents into solid tumors, giving Lisata a differentiated platform that could support multiple combination therapies if clinical development validates its approach.
Negative Factors
Limited Commercial Revenue
Lisata lacks recurring product revenue from commercialized drugs, while losses remain far larger than sales. This leaves the business dependent on clinical success, partnerships or external capital rather than internally funded growth.
Read all positive and negative factors
Positive Factors
Negative Factors
Proprietary Oncology Platform
CEND is designed to improve delivery of anti-cancer agents into solid tumors, giving Lisata a differentiated platform that could support multiple combination therapies if clinical development validates its approach.
Read all positive factors

Lisata Therapeutics (LSTA) vs. SPDR S&P 500 ETF (SPY)

Lisata Therapeutics Business Overview & Revenue Model

Company Description
Lisata Therapeutics, Inc. is a clinical-stage biopharmaceutical firm focused on pioneering and bringing to market cellular therapies. These treatments are designed to either reverse disease progression or facilitate the repair of damaged bodily ti...
How the Company Makes Money
Lisata Therapeutics does not have publicly disclosed recurring product revenue from commercialized drugs; as a clinical-stage biotech, its ability to generate revenue is primarily tied to external funding rather than ongoing sales. The company typ...

Lisata Therapeutics Financial Statement Overview

Summary
Very weak fundamentals: TTM revenue is minimal ($0.1M) and declining (-41.2%), while profitability and cash generation are deeply negative (TTM net income -$14.6M; operating and free cash flow both -$15.4M). The main positive is no debt (debt-to-equity 0.0), but equity has been shrinking (down to $8.2M TTM), increasing dilution/financing risk.
Income Statement
12
Very Negative
Balance Sheet
46
Neutral
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue100.00K170.00K1.00M0.000.000.00
Gross Profit95.00K24.00K1.00M0.000.000.00
EBITDA-16.01M-17.40M-20.61M-22.98M-56.63M-28.92M
Net Income-14.62M-16.59M-19.98M-20.84M-54.23M-27.47M
Balance Sheet
Total Assets11.03M17.74M35.00M54.69M73.03M97.01M
Cash, Cash Equivalents and Short-Term Investments10.44M15.96M31.25M50.53M69.23M94.97M
Total Debt0.000.00137.00K168.00K485.00K714.00K
Total Liabilities3.04M3.14M5.68M6.80M6.71M5.01M
Stockholders Equity8.24M14.86M29.57M48.15M66.58M92.25M
Cash Flow
Free Cash Flow-12.32M-15.98M-19.36M-20.03M-21.45M-22.30M
Operating Cash Flow-12.32M-15.95M-19.36M-20.03M-21.17M-22.25M
Investing Cash Flow5.15M15.09M13.23M10.10M28.91M-54.90M
Financing Cash Flow768.00K599.00K-206.00K385.00K-224.00K85.28M

Lisata Therapeutics Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price1.82
Price Trends
50DMA
2.03
Negative
100DMA
2.67
Negative
200DMA
3.13
Negative
Market Momentum
MACD
-0.02
Negative
RSI
58.27
Neutral
STOCH
66.93
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For LSTA, the sentiment is Neutral. The current price of 1.82 is above the 20-day moving average (MA) of 1.46, below the 50-day MA of 2.03, and below the 200-day MA of 3.13, indicating a neutral trend. The MACD of -0.02 indicates Negative momentum. The RSI at 58.27 is Neutral, neither overbought nor oversold. The STOCH value of 66.93 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for LSTA.

Lisata Therapeutics Risk Analysis

Lisata Therapeutics disclosed 83 risk factors in its most recent earnings report. Lisata Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Lisata Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$5.75M-0.39-394.24%90.37%
48
Neutral
$60.38M-3.24288.40%86.10%
46
Neutral
$16.13M-0.28-67.15%57.48%
45
Neutral
$3.15M>-0.01-201.49%99.41%
43
Neutral
$14.87M-1.13-113.79%0.03%-90.65%26.48%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
LSTA
Lisata Therapeutics
1.86
-0.34
-15.45%
APVO
Aptevo Therapeutics
1.88
-25.66
-93.17%
CTXR
Citius Pharmaceuticals
0.60
-0.61
-50.41%
PCSA
Processa Pharmaceuticals
2.16
-2.33
-51.89%
APLM
Apollomics
24.50
18.75
326.09%

Lisata Therapeutics Corporate Events

Business Operations and StrategyExecutive/Board ChangesLegal Proceedings
Lisata Therapeutics Announces Major Workforce Reduction and Retrenchment
Negative
Aug 4, 2026
On August 3, 2026, Lisata Therapeutics’ board approved an immediate workforce reduction of approximately 72%, a drastic cost-cutting move intended to lower operating expenses and support a search for strategic options. The company expects ab...
Business Operations and StrategyLegal ProceedingsM&A Transactions
Lisata Therapeutics Ends Kuva Merger, Starts Strategic Review
Negative
Jul 24, 2026
On July 24, 2026, Lisata Therapeutics terminated its March 6, 2026 merger agreement with Kuva Labs and Kuva Acquisition Corp. after the buyer failed to accept and pay for tendered shares when the offer expired on July 20, 2026. Kuva Labs informed ...
Business Operations and StrategyM&A Transactions
Lisata Therapeutics Extends Merger Timeline with Kuva Labs
Neutral
Jul 17, 2026
On July 16, 2026, Lisata Therapeutics, Inc. and Kuva Labs Inc., along with Kuva Acquisition Corp., amended their previously announced March 6, 2026 Agreement and Plan of Merger. The amendment extends the transaction’s contractual Outside Dat...
Business Operations and StrategyM&A TransactionsPrivate Placements and Financing
Lisata Therapeutics Amends Kuva Labs Merger Agreement Timeline
Negative
Jun 9, 2026
On June 8, 2026, Lisata Therapeutics, Kuva Labs and its subsidiary Kuva Acquisition Corp. amended their March 6, 2026 merger agreement, extending the deadline to commence the tender offer for Lisata’s outstanding common shares to June 10, 20...
M&A Transactions
Lisata Therapeutics Faces Uncertainty in Kuva Tender Offer
Negative
Jun 1, 2026
On May 29, 2026, Lisata Therapeutics, Kuva Labs and Kuva Acquisition Corp. amended their March 6, 2026 merger agreement so that the tender offer for all outstanding Lisata common shares would commence on June 1, 2026 instead of May 29, 2026, or on...
Business Operations and StrategyM&A Transactions
Lisata Therapeutics Revises Merger Terms, Adds Milestone CVRs
Neutral
May 29, 2026
On May 29, 2026, Lisata Therapeutics, Kuva Labs and its acquisition subsidiary amended their March 6, 2026 merger agreement, revising the offer for Lisata’s common stock from $5.00 in cash plus a $1.00 contingent value right to $4.00 in cash...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 25, 2026