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Lantheus Holdings Inc (LNTH)
NASDAQ:LNTH
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Lantheus (LNTH) AI Stock Analysis

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LNTH

Lantheus

(NASDAQ:LNTH)

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Outperform 72 (OpenAI - 5.2)
Rating:72Outperform
Price Target:
$113.00
▲(7.80% Upside)
Action:Reiterated
Date:08/06/26
LNTH’s score is driven primarily by strong financial performance, led by robust operating and free cash flow generation and solid operating margins, partially offset by net income volatility and moderate leverage. Corporate events are supportive due to the announced take-private deal with cash consideration and CVR upside. Technical signals are mixed (negative MACD and below short-term moving averages), while valuation is moderate with no dividend yield support included. Earnings call tone is balanced: guidance was reaffirmed and regulatory progress noted, but near-term margin and competitive pressures remain.
Positive Factors
Cash generation
Sustained high operating and free cash flow provides durable internal funding for commercialization, manufacturing scale-up, and R&D without relying on equity issuance. This supports meeting CVR-linked milestones, servicing debt, and funding integration or new product launches over the next 2–6 months.
Negative Factors
Net income volatility
Below-the-line volatility driven by nonrecurring charges, amortization and other adjustments makes earnings less predictable. That unpredictability can complicate covenant management, CVR achievement forecasting, and capital-allocation planning across the next several quarters.
Read all positive and negative factors
Positive Factors
Negative Factors
Cash generation
Sustained high operating and free cash flow provides durable internal funding for commercialization, manufacturing scale-up, and R&D without relying on equity issuance. This supports meeting CVR-linked milestones, servicing debt, and funding integration or new product launches over the next 2–6 months.
Read all positive factors

Lantheus (LNTH) vs. SPDR S&P 500 ETF (SPY)

Lantheus Business Overview & Revenue Model

Company Description
Lantheus Holdings, Inc. is a global pharmaceutical company dedicated to the development, manufacturing, and commercialization of advanced diagnostic and therapeutic agents. Their mission is to empower clinicians worldwide in the accurate diagnosis...
How the Company Makes Money
Lantheus makes money primarily by selling diagnostic imaging agents (radiopharmaceuticals and related imaging products) to healthcare providers (e.g., hospitals, imaging centers) and distributors, generating product revenue per dose/unit shipped. ...

Lantheus Earnings Call Summary

Earnings Call Date:May 07, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Oct 29, 2026
Earnings Call Sentiment Neutral
The call contained meaningful positives — regulatory progress with PYLARIFY TRUVU approval, solid cash generation, NEUROCEQ and DEFINITY growth, and a reaffirmed full-year outlook — balanced against near-term profitability pressure driven by lower oncology reported revenue, higher operating expenses from recent acquisitions and investments, competitive and pricing risks in PSMA PET, and regulatory timing uncertainty for some therapeutic assets. Management emphasized disciplined capital allocation and readiness to launch TRUVU, and expects growth acceleration in 2027, but near-term headwinds keep the tone measured.
Positive Updates
FDA Approval of PYLARIFY TRUVU
FDA approved PYLARIFY TRUVU on March 6, 2026. The new formulation offers larger batch sizes and improved stability at higher radioactive concentrations, enabling broader geographic reach and supply flexibility. Management estimates >70% of current PYLARIFY supply is produced at PMF sites equipped to realize TRUVU advantages.
Negative Updates
Oncology Revenue Decline (PYLARIFY reported revenue)
Oncology revenue (PYLARIFY) was $240.9 million in Q1, down 6.5% year-over-year despite volume growth, reflecting net price pressure and competitive dynamics in the PSMA PET space.
Read all updates
Q1-2026 Updates
Negative
FDA Approval of PYLARIFY TRUVU
FDA approved PYLARIFY TRUVU on March 6, 2026. The new formulation offers larger batch sizes and improved stability at higher radioactive concentrations, enabling broader geographic reach and supply flexibility. Management estimates >70% of current PYLARIFY supply is produced at PMF sites equipped to realize TRUVU advantages.
Read all positive updates
Company Guidance
Lantheus reiterated full‑year 2026 guidance of $1.40–$1.45 billion in revenue and $5.00–$5.25 in adjusted EPS while citing a strong Q1 start: Q1 revenue $377.3M (+1.2% YoY; +8.6% ex‑$25.2M divested spec revenue), reported net income $118.4M and adjusted net income $95.8M (‑12.5% YoY), GAAP diluted EPS $1.80 and adjusted EPS $1.46 (down ~4.6%), operating profit $129.1M (‑10.5%), gross margin 67.0%, operating expenses 32.8% of revenue, and an effective tax rate of 25.3%; product level Q1 results included PYLARIFY $240.9M (‑6.5% YoY; U.S. volume +5.8% YoY), NEUROCEQ $35.4M (+14.3% vs Q4 2025), DEFINITY $84.6M (+6.8% YoY) and strategic partnerships $16.3M (+52.1%). Cash generation remained strong with operating cash flow $125.1M, capex $3.2M, free cash flow $121.9M, cash & equivalents $498.6M, $200M remaining on the buyback authorization and a $750M undrawn revolver; management said guidance is being maintained out of prudence given competitive dynamics and an upcoming CEO transition, while expecting growth acceleration beginning in 2027.

Lantheus Financial Statement Overview

Summary
Strong cash generation (TTM operating cash flow ~$413M; free cash flow ~$388M; very strong TTM FCF growth) and healthy operating profitability support a solid base. The main offset is bottom-line volatility, with TTM net income down materially versus prior years despite strong margins, and a balance sheet that is improved but still carries a moderate debt load.
Income Statement
74
Positive
Balance Sheet
67
Positive
Cash Flow
86
Very Positive
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue1.56B1.54B1.53B1.30B935.06M425.21M
Gross Profit936.02M941.95M988.29M709.54M581.70M187.69M
EBITDA465.39M403.64M515.27M491.00M81.83M-25.00M
Net Income275.31M233.56M312.44M326.66M28.07M-71.28M
Balance Sheet
Total Assets2.41B2.23B1.98B1.65B1.32B863.78M
Cash, Cash Equivalents and Short-Term Investments593.30M359.12M912.81M713.66M415.65M98.51M
Total Debt624.96M619.43M619.44M616.95M583.51M191.31M
Total Liabilities1.10B1.14B892.33M835.26M874.11M399.35M
Stockholders Equity1.31B1.09B1.09B815.89M447.15M464.44M
Cash Flow
Free Cash Flow509.73M354.05M493.13M258.70M263.43M41.78M
Operating Cash Flow537.93M390.14M544.75M305.26M281.78M53.92M
Investing Cash Flow-281.03M-627.17M-226.01M5.94M-276.55M3.68M
Financing Cash Flow-218.69M-316.58M-118.54M-13.06M311.69M-39.33M

Lantheus Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price104.82
Price Trends
50DMA
103.97
Negative
100DMA
95.93
Positive
200DMA
81.20
Positive
Market Momentum
MACD
-0.90
Positive
RSI
43.26
Neutral
STOCH
17.58
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For LNTH, the sentiment is Neutral. The current price of 104.82 is above the 20-day moving average (MA) of 101.79, above the 50-day MA of 103.97, and above the 200-day MA of 81.20, indicating a neutral trend. The MACD of -0.90 indicates Positive momentum. The RSI at 43.26 is Neutral, neither overbought nor oversold. The STOCH value of 17.58 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for LNTH.

Lantheus Risk Analysis

Lantheus disclosed 67 risk factors in its most recent earnings report. Lantheus reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Lantheus Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
72
Outperform
$6.59B23.9723.27%2.35%7.38%
70
Outperform
$1.75B15.7319.19%30.90%
66
Neutral
$2.23B124.261.43%-8.81%-96.21%
60
Neutral
$5.88B37.03-326.75%9.28%4917.17%
56
Neutral
$2.81B-25.50-10.42%24.85%-264.42%
54
Neutral
$1.78B-1.03-55.97%11.50%-4.18%-2138.82%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
LNTH
Lantheus
100.26
45.11
81.80%
PRGO
Perrigo Company
12.97
-8.77
-40.35%
SUPN
Supernus Pharmaceuticals
49.03
7.03
16.74%
ANIP
ANI Pharmaceuticals
76.87
-13.25
-14.70%
HCM
HUTCHMED
12.64
-3.57
-22.02%
AMRX
Amneal Pharmaceuticals
18.19
8.86
94.96%

Lantheus Corporate Events

Business Operations and StrategyDelistings and Listing ChangesM&A Transactions
Curium to Acquire Lantheus, Taking Company Private
Positive
Aug 4, 2026
On August 3, 2026, Lantheus agreed to be acquired by Curium US Holdings via a merger that will take Lantheus private as a wholly owned subsidiary, with shareholders receiving $102.50 in cash per share plus a non-tradeable contingent value right of...
Business Operations and StrategyM&A TransactionsPrivate Placements and Financing
Curium to Acquire Lantheus in $8 Billion Merger
Positive
Aug 3, 2026
On August 3, 2026, Curium US Holdings and Lantheus agreed to a merger in which Curium will acquire all Lantheus shares for $102.50 in cash at closing, plus up to $12.00 per share in non-transferable contingent value rights tied to 2030 sales miles...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 06, 2026