OPK Stock Chart & Stats
500.00
125.00(33.33%)
At close: 4:00 PM EDT
500.00
125.00(33.33%)
Day’s Range― - ―
52-Week Range310.00 - 516.90
Previous CloseN/A
Volume1.32M
Average Volume (3M)277.10K
Market Cap
₪3.12B
Enterprise Value1.23K
Total Cash (Recent Filing)₪300.76M
Total Debt (Recent Filing)₪392.26M
Price to Earnings (P/E)―
Beta0.02
Next Earnings
Nov 11, 2026EPS Estimate
-21.46Next Dividend Ex-DateN/A
Dividend YieldN/A
Share Statistics
EPS (TTM)-0.10
Shares Outstanding746,328,250
10 Day Avg. Volume233,795
30 Day Avg. Volume277,104
Financial Highlights & Ratios
PEG Ratio-0.01
Price to Book (P/B)0.75
Price to Sales (P/S)1.56
P/FCF Ratio-4.96
Enterprise Value/Market CapN/A
Enterprise Value/RevenueN/A
Enterprise Value/Gross ProfitN/A
Enterprise Value/EbitdaN/A
Forecast
1Y Price Target
₪923.30Price Target Upside84.66% Upside
Rating ConsensusModerate Buy
Number of Analyst Covering3
EPS Forecast (FY)-91.33
Revenue Forecast (FY)₪161.62B
Bulls Say, Bears Say
Bulls Say
Revenue Re-accelerationA large TTM revenue inflection (+116.6% YoY) signals durable demand improvement and better commercialization execution across pharma and services. That scale lift improves the company's ability to leverage fixed costs and supports longer-term margin recovery if revenue mix and pricing hold.
Strong Liquidity RunwayA >$300M cash balance provides meaningful runway to fund ongoing R&D, clinical programs and operations over the next several quarters without immediate financing. It also gives strategic optionality for partnerships, milestone funding or opportunistic buybacks that support execution flexibility.
Advanced Pipeline & Tier‑one CollaborationsMultiple clinical assets plus collaborations with Merck, Regeneron and BARDA create durable technical and commercial optionality. Tier‑one partnerships reduce single‑program risk, provide non‑dilutive funding and potential milestone/royalty upside that can materially diversify long‑term revenue sources.
Bears Say
Negative Operating & Free Cash FlowSustained negative OCF and FCF indicate the business still consumes cash despite revenue gains, raising reliance on existing cash, financings or asset monetizations. Continued cash burn constrains reinvestment and increases execution risk if revenue or partner funding do not materialize as planned.
Persistent GAAP Losses And Weak MarginsDespite higher sales, negative operating and net margins show the company has not yet converted growth into sustainable profitability. Low gross margins (~22.7%) and negative ROE reflect structural profitability weakness that could limit internal funding for R&D or commercialization unless margins improve.
Diagnostics Commercial & Reimbursement UncertaintyThe diagnostics business faces structural headwinds from prior divestitures and pending reimbursement decisions for 4Kscore. Durable expansion into primary‑care/payer channels is contingent on CMS actions, making meaningful commercial upside unlikely until policy and payer coverage shift, prolonging near‑term revenue risk.
Opko Health News
OPK FAQ
What was Opko Health Inc’s price range in the past 12 months?
Opko Health Inc lowest stock price was 310.00 and its highest was 516.90 in the past 12 months.
What is Opko Health Inc’s market cap?
Opko Health Inc’s market cap is ₪3.12B.
When is Opko Health Inc’s upcoming earnings report date?
Opko Health Inc’s upcoming earnings report date is Nov 11, 2026 which is in 103 days.
How were Opko Health Inc’s earnings last quarter?
Opko Health Inc released its earnings results on Jul 27, 2026. The company reported -3.065 earnings per share for the quarter, beating the consensus estimate of -24.52 by 21.455.
Is Opko Health Inc overvalued?
According to Wall Street analysts Opko Health Inc’s price is currently Undervalued.
Does Opko Health Inc pay dividends?
Opko Health Inc does not currently pay dividends.
What is Opko Health Inc’s EPS estimate?
Opko Health Inc’s EPS estimate is -21.46.
How many shares outstanding does Opko Health Inc have?
Opko Health Inc has 746,328,250 shares outstanding.
What happened to Opko Health Inc’s price movement after its last earnings report?
Opko Health Inc reported an EPS of -3.065 in its last earnings report, beating expectations of -24.52. Following the earnings report the stock price went up 33.333%.
Which hedge fund is a major shareholder of Opko Health Inc?
Currently, no hedge funds are holding shares in IL:OPK
What is the TipRanks Smart Score and how is it calculated?
Smart Score combines eight research factors - such as analyst recommendations, hedge fund trends, and technical indicators - to measure a stock’s outlook. These signals are unified into a single score that reflects bullish or bearish momentum. See detailed methodology
Opko Health Stock Smart Score
Outperform
1
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4
5
6
7
8
9
10
Analyst Consensus
Moderate Buy
Average Price Target:
₪923.30 (84.66% Upside)
₪923.30 (84.66% Upside)
Blogger Sentiment
Neutral
IL:OPK Sentiment 50%
Sector Average ―
Sector Average ―
News Sentiment
Very Bullish
Bullish news 83%
Bearish news 17%
Bearish news 17%
Technicals
SMA
Positive
20 days / 200 days
Momentum
-12.85%
12-Months-Change
Fundamentals
Return on Equity
―
Trailing 12-Months
Asset Growth
-7.28%
Trailing 12-Months
Company Description
Opko Health Inc
OPKO Health, Inc. operates as a healthcare enterprise with a dual focus on diagnostics and pharmaceuticals. Its operations span the United States, Ireland, Chile, Spain, Israel, Mexico, and other international markets. The company's Diagnostics division encompasses BioReference Laboratories, which delivers a comprehensive suite of laboratory testing services. These services are crucial for disease detection, diagnosis, evaluation, monitoring, and treatment, covering areas such as esoteric testing, molecular diagnostics, anatomical pathology, genetics, women's health, and correctional healthcare. BioReference serves a diverse client base, including medical practices, clinics, hospitals, employers, and government entities. Additionally, this segment provides a cutting-edge diagnostic instrument system designed for immediate, point-of-care blood test results, alongside its specialized 4Kscore testing for prostate cancer. Within the Pharmaceutical segment, OPKO offers a range of therapeutic products and a robust development pipeline. Key offerings include Rayaldee, indicated for the management of secondary hyperparathyroidism in adults suffering from stage 3 or 4 chronic kidney disease and vitamin D insufficiency. The pipeline features OPK88004, an investigational orally administered selective androgen receptor modulator; OPK88003, a peptide administered once weekly currently in Phase IIb trials for the treatment of type 2 diabetes and obesity; and hGH-CTP, a once-weekly human growth hormone injection that has successfully completed Phase III clinical trials in collaboration with Pfizer, Inc. A core strategy for this segment involves the development and commercialization of proprietary, extended-release versions of existing therapeutic proteins. Furthermore, OPKO Health supplies specialty active pharmaceutical ingredients (APIs) and is involved in the development, manufacturing, marketing, and sale of pharmaceutical, nutraceutical, veterinary, and ophthalmic products. The company also commercializes food supplements and over-the-counter products, produces and sells items primarily within the generics market, and handles the import, marketing, distribution, and sales of pharmaceutical products across various therapeutic areas, including cardiovascular conditions, vaccines, antibiotics, gastro-intestinal ailments, and hormone-related treatments, among others. Its pharmaceutical operations are further bolstered by platforms situated in Ireland, Chile, Spain, and Mexico. Founded in 1991, OPKO Health, Inc. maintains its corporate headquarters in Miami, Florida.
OPK Earnings Call
Q2 2026
0:00 / 0:00
Earnings Call Sentiment|Positive
The call conveyed materially positive operational and financial momentum: substantial pipeline progress across ModeX and OPKO biologics, significant revenue growth in the Pharmaceutical segment, a stronger cash position (> $300M), improved consolidated results (much smaller net loss) and upgraded full-year revenue guidance. However, the company faces near-term headwinds including a year-over-year decline in diagnostics revenue tied to prior divestitures, elevated and persistent operating and R&D expenses, timing/reimbursement uncertainty for 4Kscore expansion, and clinical data/enrollment timing risks. Overall, the positive items (cash runway, pipeline advances, large revenue inflection items and much improved profitability metrics) outweigh the lowlights, but several execution and timing risks warrant monitoring.View all IL:OPK earnings summariesOPK Stock 12 Month Forecast
Average Price Target
923.30
▲(84.66% Upside)












