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Ginkgo Bioworks Holdings, Inc. (DNA)
NYSE:DNA
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Ginkgo Bioworks Holdings (DNA) AI Stock Analysis

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DNA

Ginkgo Bioworks Holdings

(NYSE:DNA)

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Neutral 50 (OpenAI - 5.2)
Rating:50Neutral
Price Target:
$7.50
▲(1.90% Upside)
Action:Reiterated
Date:08/06/26
DNA scores lowest on financial performance due to shrinking revenue, very large operating losses, and continued negative free cash flow, partially offset by strong gross margins and positive equity. Technicals are moderately supportive with the stock trading above major moving averages, but momentum signals are mixed and volatility is high. The earnings call adds some support via reaffirmed cash-burn guidance, strong liquidity, and reduced cloud commitments, but near-term revenue and profitability trends remain unfavorable; valuation provides limited help given the negative P/E and no dividend yield data.
Positive Factors
High gross margin (strong unit economics)
An ~86.9% TTM gross margin indicates favorable unit economics on delivered services. Durable high gross margins give room to absorb fixed R&D and automation costs, improve leverage as volume recovers, and increase the potential value capture from downstream royalties and licensing.
Negative Factors
Shrinking revenue base
A multi-year collapse in revenue materially weakens operating leverage and the firm's ability to cover fixed costs. Persistently lower top-line reduces the runway for scaling automation economics, slows attainment of sustainable margins, and raises risk that investments won’t be fully monetized.
Read all positive and negative factors
Positive Factors
Negative Factors
High gross margin (strong unit economics)
An ~86.9% TTM gross margin indicates favorable unit economics on delivered services. Durable high gross margins give room to absorb fixed R&D and automation costs, improve leverage as volume recovers, and increase the potential value capture from downstream royalties and licensing.
Read all positive factors

Ginkgo Bioworks Holdings Key Performance Indicators (KPIs)

Any
Any
Operating Income by Segment
Operating Income by Segment
Reveals profitability across different business units, highlighting which segments drive earnings and where there may be challenges or opportunities for growth.
Chart InsightsCell Engineering’s outsized operating losses from 2022–early 2023 have narrowed materially since late 2024, suggesting meaningful cost discipline, project rationalization, or early revenue realization that materially cuts cash burn. Biosecurity, which delivered strong, lumpy profits in 2021–2022, has normalized into modest, steady losses—consistent with waning one‑off contract tailwinds. Together these moves point to a shift from heavy scale‑up spending toward operational consolidation, but persistent quarter‑to‑quarter volatility means profitability still hinges on sustained commercial wins or new large contracts.
Data provided by:The Fly

Ginkgo Bioworks Holdings (DNA) vs. SPDR S&P 500 ETF (SPY)

Ginkgo Bioworks Holdings Business Overview & Revenue Model

Company Description
Ginkgo Bioworks Holdings, Inc., together with its subsidiaries, develops a platform for cell engineering in the United States. It operates through the Cell Engineering and Biosecurity segments. The company offers cell engineering research and deve...
How the Company Makes Money
Ginkgo primarily generates revenue through two broad models: (1) platform (foundry) services and (2) downstream value participation. Platform services revenue comes from customer-funded programs where Ginkgo performs R&D work—such as organism/stra...

Ginkgo Bioworks Holdings Earnings Call Summary

Earnings Call Date:Aug 05, 2026
(Q2-2026)
|
% Change Since: |
Next Earnings Date:Nov 16, 2026
Earnings Call Sentiment Neutral
The call balanced significant strategic and operational progress with near-term financial headwinds. Positives include major academic and national lab contracts, rapid expansion and scale demonstration of Nebula, a competitive ADME product with strong price/performance and a solid cash position plus a reduced long‑term Google Cloud commitment. Negatives include steep year‑over‑year revenue declines, wider GAAP losses and worse adjusted EBITDA in Q2, elevated quarter‑specific cash burn and ongoing excess lease costs. Management emphasizes cost discipline, a shift toward investing in autonomous labs and predictable cash burn guidance for 2026, but revenue recognition timing for automation deals and the need to further mature operations create near‑term uncertainty.
Positive Updates
Strategic NSF and Academic Wins
Selected to build autonomous labs for MIT, Caltech, University of Maryland and Northwestern (NSF-funded or separate grant for MIT), positioning Ginkgo as a supplier of campus cloud/autonomous labs and training the next generation of scientists.
Negative Updates
Sharp Revenue Decline
Q2 2026 revenue was $20M, down 48% YoY; revenue for the first 6 months of 2026 was $40M, down 49% YoY (or ~42% decline excluding $7.5M noncash revenue in H1 2025 related to BiomEdit).
Read all updates
Q2-2026 Updates
Negative
Strategic NSF and Academic Wins
Selected to build autonomous labs for MIT, Caltech, University of Maryland and Northwestern (NSF-funded or separate grant for MIT), positioning Ginkgo as a supplier of campus cloud/autonomous labs and training the next generation of scientists.
Read all positive updates
Company Guidance
Management reaffirmed full‑year 2026 cash‑burn guidance of $125 million to $150 million while saying they expect further cash‑burn improvement in H2; the company enters H2 with $302 million of cash and cash equivalents plus $87 million of restricted cash. Key Q2 and H1 metrics cited: Q2 revenue $20 million (down 48% YoY) and H1 revenue $40 million (down 49% YoY; ~42% decline ex. $7.5 million non‑cash BiomEdit item), R&D $30 million in Q2 (down 4% YoY), G&A $12 million in Q2 (down 26% YoY), net loss from continuing operations of $57 million in Q2 (vs $53 million prior year), and adjusted EBITDA of negative $36 million in Q2 (vs negative $25 million), which includes $14 million of excess‑lease carrying costs (up from $12 million). Cash‑burn was $45 million in Q2 and $93 million in the first half (down 3% from $96 million), noting a $17 million ATM raise (excluded from cash‑burn) and a $14 million Google Cloud payment in Q1 that raised near‑term burn; the Google Cloud reset reduced future minimum commitments by more than $100 million and extended the term from 3 to 6 years.

Ginkgo Bioworks Holdings Financial Statement Overview

Summary
Overall fundamentals are weak: revenue has contracted sharply (2022 $477.7M to 2025 $170.2M; TTM $111.9M) with negative TTM growth (-20.8%) and extremely large losses (TTM EBIT margin ~-330%, net margin ~-403%). Positives include very strong gross margin (~86.9%) and positive equity ($420.3M), but ongoing cash burn (TTM operating cash flow -$167.9M; TTM free cash flow -$187.8M) and higher leverage (debt-to-equity ~0.96) keep financial risk elevated despite improved FCF versus prior years.
Income Statement
22
Negative
Balance Sheet
46
Neutral
Cash Flow
28
Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue111.86M170.16M227.04M251.46M477.71M313.84M
Gross Profit89.59M138.63M188.49M197.45M273.49M184.15M
EBITDA-209.15M-254.61M-484.39M-821.29M-2.06B-1.81B
Net Income-290.80M-312.76M-547.03M-892.87M-2.10B-1.83B
Balance Sheet
Total Assets990.05M1.12B1.38B1.67B2.54B2.07B
Cash, Cash Equivalents and Short-Term Investments302.16M422.62M561.57M944.07M1.32B1.55B
Total Debt404.11M439.88M467.73M239.31M442.59M23.03M
Total Liabilities569.76M611.11M661.39M568.19M803.04M503.61M
Stockholders Equity420.28M508.59M716.06M1.10B1.74B1.51B
Cash Flow
Free Cash Flow-190.12M-178.72M-382.13M-336.30M-304.47M-310.34M
Operating Cash Flow-170.24M-171.06M-319.58M-295.50M-252.20M-253.82M
Investing Cash Flow56.50M-240.29M-62.24M-80.69M-67.39M-73.26M
Financing Cash Flow34.55M17.77M-1.74M-3.22M95.34M1.53B

Ginkgo Bioworks Holdings Technical Analysis

Technical Analysis Sentiment
Negative
Last Price7.36
Price Trends
50DMA
8.53
Negative
100DMA
8.26
Negative
200DMA
8.53
Negative
Market Momentum
MACD
-0.40
Positive
RSI
36.29
Neutral
STOCH
4.15
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DNA, the sentiment is Negative. The current price of 7.36 is below the 20-day moving average (MA) of 7.87, below the 50-day MA of 8.53, and below the 200-day MA of 8.53, indicating a bearish trend. The MACD of -0.40 indicates Positive momentum. The RSI at 36.29 is Neutral, neither overbought nor oversold. The STOCH value of 4.15 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for DNA.

Ginkgo Bioworks Holdings Risk Analysis

Ginkgo Bioworks Holdings disclosed 69 risk factors in its most recent earnings report. Ginkgo Bioworks Holdings reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Ginkgo Bioworks Holdings Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
69
Neutral
$238.96M15.2920.50%10.99%-12.12%
63
Neutral
$1.58B-11.55-63.58%-62.28%15.36%
57
Neutral
$758.74M-49.78-13.08%29.73%
55
Neutral
$1.57B-9.20-49.11%91.41%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$457.24M-1.38-60.21%-51.54%7.05%
43
Neutral
$341.85M-0.85-91.62%-55.00%51.58%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DNA
Ginkgo Bioworks Holdings
6.92
-5.02
-42.04%
NAGE
Niagen Bioscience
3.04
-6.59
-68.43%
MNPR
Monopar Therapeutics Inc
116.49
82.98
247.63%
LYEL
Lyell Immunopharma
13.55
2.72
25.12%
JBIO
Jade Biosciences
23.45
16.09
218.61%
ABSI
AbSci
9.24
6.62
252.67%

Ginkgo Bioworks Holdings Corporate Events

Business Operations and StrategyFinancial Disclosures
Ginkgo Bioworks to Review Q2 2026 Performance
Neutral
Jul 30, 2026
Ginkgo Bioworks Holdings, Inc., a synthetic biology tools provider offering autonomous, robotics-powered labs and cloud-based contract research services, focuses on making biological engineering more accessible and productive for scientists and co...
Executive/Board ChangesShareholder Meetings
Ginkgo Bioworks Shareholders Back Board, Governance Structure
Positive
Jun 12, 2026
On June 11, 2026, Ginkgo Bioworks Holdings, Inc. held its 2026 annual meeting of shareholders, with approximately 77.15% of the combined Class A and Class B shares and 93.77% of Class B shares represented. Shareholders confirmed the company’...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 06, 2026