Successful TECELRA Launch and Revenue Guidance
Adaptimmune launched TECELRA and provided full-year 2025 revenue guidance of $35 million to $45 million, with 21 patients apheresed so far in 2025 and 14 treatments invoiced, generating $4 million in Q1 net sales.
Efficient Manufacturing Operations
Achieved 100% manufacturing success rate from the U.S. TECELRA manufacturing center, with no capacity issues and an average turnaround time from apheresis to lot release of 27 days, beating the target of 30 days.
Expansion of Authorized Treatment Centers (ATCs)
Adaptimmune has 28 centers accepting referrals for TECELRA and anticipates having the full network of approximately 30 ATCs operational by the end of 2025, a year earlier than expected.
Regulatory Engagement and Future Plans
Progressed regulatory plans for lete-cel, with rolling BLA initiation anticipated before the end of 2025. Lete-cel has the potential to double the addressable patient population in the sarcoma franchise.
Positive Market Reception
No patient denials for TECELRA have been reported, indicating effective patient access and positive reception from the medical community.