Sustained UnprofitabilityPersistent negative margins and reported losses constrain internal funding for growth and increase reliance on external capital. Over several quarters this limits ability to reinvest, may dilute shareholders if funded by equity, and raises execution risk for commercial scaling.
Negative Operating Cash FlowOperating cash flow deficits mean day-to-day operations do not generate sufficient cash, forcing dependence on financing or reserves. This weak cash generation limits capacity to expand manufacturing, support sales channels, or sustain clinical programs without outside funding in the medium term.
Product Concentration RiskRevenue is concentrated around a single commercial product while other assets remain pre-commercial. That concentration makes medium-term performance highly sensitive to Remplir adoption, reimbursement and regulatory outcomes, raising structural execution and market-acceptance risk.