tiprankstipranks
Trending News
More News >
AbCellera Biologics (ABCL)
NASDAQ:ABCL

AbCellera Biologics (ABCL) AI Stock Analysis

Compare
1,730 Followers

Top Page

AB

AbCellera Biologics

(NASDAQ:ABCL)

45Neutral
AbCellera Biologics is currently facing significant financial and technical challenges, with declining revenues and weak technical indicators. Strategic advancements in drug development and a strong liquidity position offer some potential, but current valuation metrics are concerning. The recent patent appeal win and Health Canada approval are positive developments but not sufficient to fully offset the negatives.
Positive Factors
Financial Position
ABCL is leveraging its large $800M+ liquidity position to cultivate an internal pipeline and high-value strategic partnerships.
Market Potential
The new treatment targets a sizable market with high unmet needs, as nearly 40 million women in the US present with undertreated hot flashes.
Strategic Partnerships
AbCellera succeeded in signing two new partnerships in 2024, with Biogen and venture firms Viking and ArrowMark, and expanding two legacy programs.
Negative Factors
Competition
Leading NK3R competitors, including Astellas' Veozah and Bayer's elinzanetant, have a head start on ABCL-635.
Financial Performance
AbCellera Biologics reported financial results for their 4Q24, including revenues of $5.1 million and a net loss of ($0.12) per share, as compared to revenues of $9.2 million and a net loss of ($0.16) per share in the prior year period.
Revenue Expectations
ABCL's 4Q24 revenue of $5.0M fell below expectations as ABCL continues to wind down partner program activity.

AbCellera Biologics (ABCL) vs. S&P 500 (SPY)

AbCellera Biologics Business Overview & Revenue Model

Company DescriptionAbCellera Biologics Inc. develops antibody discovery platform. Its full-stack, artificial intelligence-powered antibody discovery platform searches and analyzes the database of natural immune systems to find antibodies that could be developed as drugs. As of December 31, 2021, the company had 156 discovery programs that are either completed, in progress, or under contract with 36 partners. AbCellera Biologics Inc. has a research collaboration and license agreement with Eli Lilly and Company. The company was incorporated in 2012 and is headquartered in Vancouver, Canada.
How the Company Makes MoneyAbCellera Biologics generates revenue through collaborations and partnerships with pharmaceutical and biotechnology companies. Its revenue model primarily involves upfront payments, milestone payments, and royalties. The company leverages its technology platform to provide discovery services, identifying potential therapeutic antibodies that partners can then further develop and commercialize. AbCellera enters into agreements where it receives payments upon achieving certain development and regulatory milestones, as well as a percentage of sales (royalties) from any successfully commercialized products. Significant partnerships with major industry players, such as Eli Lilly, contribute to its earnings by providing a steady flow of collaboration opportunities and financial commitments.

AbCellera Biologics Key Performance Indicators (KPIs)

Any
Any
Number of Discovery Partners
Number of Discovery Partners
Measures the number of companies collaborating with AbCellera, showcasing the breadth of its industry relationships and potential for diversified income streams.
Chart InsightsAbCellera's number of discovery partners has grown steadily, reaching 46 by the end of 2023. However, the latest earnings call reveals a strategic shift with reduced new partnership activities, focusing instead on advancing clinical programs like ABCL635 and ABCL575. This pivot to a clinical stage biotech, despite declining revenue and increased R&D expenses, suggests a long-term strategy prioritizing high-value partnerships and clinical advancements over sheer volume of discovery collaborations.
Data provided by:Main Street Data

AbCellera Biologics Financial Statement Overview

Summary
AbCellera Biologics faces notable financial challenges, with declining revenues and profitability affecting its income statement. While the balance sheet remains relatively stable, increased debt levels and weakened cash flow metrics pose potential risks. Strategic adjustments may be required to improve financial health and operational efficiency.
Income Statement
35
Negative
AbCellera Biologics has experienced a significant decrease in revenue from 2022 to 2024, which has adversely affected its gross profit margin. The net profit margin has turned negative due to substantial losses in 2023 and 2024, indicating operational challenges. Additionally, EBIT and EBITDA margins have deteriorated, reflecting negative operating efficiency.
Balance Sheet
55
Neutral
The company maintains a strong equity base, with a favorable equity ratio. However, the debt-to-equity ratio has increased, suggesting a rising reliance on debt financing, though it remains at manageable levels. The declining return on equity indicates reduced profitability on shareholders' investments.
Cash Flow
40
Negative
Free cash flow has turned negative, and operating cash flow is not sufficient to cover net income, indicating cash management issues. The significant decline in free cash flow growth rate from 2022 to 2024 further pressures financial stability.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
28.83M38.02M485.42M375.20M233.16M
Gross Profit
28.83M38.02M418.99M329.69M206.01M
EBIT
-314.77M-237.21M216.51M204.41M156.03M
EBITDA
-204.15M-192.16M272.20M241.62M169.62M
Net Income Common Stockholders
-162.86M-146.40M158.52M153.46M118.92M
Balance SheetCash, Cash Equivalents and Short-Term Investments
625.61M760.59M886.49M722.98M594.12M
Total Assets
1.36B1.49B1.54B1.32B1.01B
Total Debt
60.74M77.38M82.26M36.41M6.10M
Net Debt
-95.58M-55.94M-304.28M-439.73M-588.01M
Total Liabilities
304.47M335.78M307.63M292.84M175.03M
Stockholders Equity
1.06B1.15B1.23B1.03B830.51M
Cash FlowFree Cash Flow
-186.95M-121.38M204.70M186.13M8.02M
Operating Cash Flow
-108.56M-43.88M277.36M244.58M22.69M
Investing Cash Flow
121.41M-221.11M-352.63M-332.25M-119.78M
Financing Cash Flow
12.77M10.36M-1.63M-3.89M683.65M

AbCellera Biologics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price2.03
Price Trends
50DMA
2.30
Negative
100DMA
2.67
Negative
200DMA
2.69
Negative
Market Momentum
MACD
-0.11
Positive
RSI
36.87
Neutral
STOCH
21.00
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ABCL, the sentiment is Negative. The current price of 2.03 is below the 20-day moving average (MA) of 2.29, below the 50-day MA of 2.30, and below the 200-day MA of 2.69, indicating a bearish trend. The MACD of -0.11 indicates Positive momentum. The RSI at 36.87 is Neutral, neither overbought nor oversold. The STOCH value of 21.00 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ABCL.

AbCellera Biologics Risk Analysis

AbCellera Biologics disclosed 102 risk factors in its most recent earnings report. AbCellera Biologics reported the most risks in the “Tech & Innovation” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

AbCellera Biologics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
74
Outperform
$837.58M4.5928.12%910.33%
63
Neutral
$781.56M222.83%29.88%35.11%
52
Neutral
$5.15B3.02-44.64%2.83%16.44%-0.47%
52
Neutral
$999.95M236.9511.62%
45
Neutral
$605.92M-15.59%-35.41%-12.26%
42
Neutral
$902.41M-51.85%0.71%
41
Neutral
$754.06M-63.56%270.02%32.69%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ABCL
AbCellera Biologics
2.03
-1.71
-45.72%
GYRE
Gyre Therapeutics
11.35
-3.08
-21.34%
XERS
Xeris Pharmaceuticals
4.88
2.83
138.05%
CVAC
CureVac
3.72
0.32
9.41%
PRAX
Praxis Precision Medicines
37.02
-7.99
-17.75%
PHVS
Pharvaris
16.56
-4.10
-19.85%

AbCellera Biologics Earnings Call Summary

Earnings Call Date:May 08, 2025
(Q1-2025)
|
% Change Since: 1.00%|
Next Earnings Date:Aug 12, 2025
Earnings Call Sentiment Neutral
The earnings call highlighted significant progress in advancing key drug candidates, particularly ABCL635 and ABCL575, alongside a strong liquidity position to support ongoing and future programs. However, the call also noted a decline in revenue and increased net loss, with some development programs paused. The sentiment reflects a balance between ongoing challenges and strategic advancements.
Q1-2025 Updates
Positive Updates
Introduction of ABCL635
ABCL635 is a potential first-in-class therapeutic antibody for non-hormonal treatment of moderate-to-severe vasomotor symptoms associated with menopause. This represents a significant market opportunity with a potential for over $2 billion in annual sales.
Strong Liquidity Position
AbCellera continues to be in a strong liquidity position with approximately $630 million in cash and equivalents and roughly $180 million in available committed government funding.
Advancement of ABCL575
ABCL575 is on track with CTA filing in Q2 and anticipated start of Phase 1 clinical trials in Q3. Preclinical data will be presented at the Society for Investigative Dermatology's Annual Meeting.
Platform and Pipeline Development
AbCellera is transitioning from a platform company to a clinical-stage biotech with a portfolio of more than 20 internal and co-development programs. Investments in clinical manufacturing capabilities are nearing completion.
Negative Updates
Revenue Decline
Revenue for Q1 2025 was about $4 million, compared to $10 million in the same quarter of 2024. This decline is attributed to a focus on internal and co-development programs and a decrease in research fee revenue.
Net Loss Increase
AbCellera reported a net loss of approximately $46 million for the quarter, compared to a loss of around $41 million in the same quarter last year.
Paused Development Programs
The development of the four Trianni-license molecules that NovaRock advanced into Phase 1 are currently paused, potentially affecting near- and mid-term revenue from milestones and royalties.
Company Guidance
During the first quarter of 2025, AbCellera focused on advancing their key priorities, including initiating Phase 1 clinical trials for ABCL635 and ABCL575, which are set to start in Q3 of 2025, with key readouts expected by mid-2026. ABCL635, a first-in-class therapeutic antibody targeting the neurokinin 3 receptor (NK3R) for non-hormonal treatment of vasomotor symptoms associated with menopause, represents a significant market opportunity, valued at over $2 billion annually. Approximately 30% of women experience these symptoms, with more than half seeking treatment. AbCellera aims to differentiate ABCL635 with a monthly injectable format preferred by over 50% of surveyed women, compared to daily oral treatments. Financially, the company maintained a strong liquidity position with $630 million in cash and equivalents and $180 million in committed government funding, despite a net loss of $46 million for the quarter, driven by R&D expenses of $43 million. The company's ongoing investments focus on internal programs and completing clinical manufacturing capabilities, which are set to come online by the end of 2025.

AbCellera Biologics Corporate Events

Product-Related AnnouncementsBusiness Operations and StrategyRegulatory Filings and Compliance
AbCellera Biologics Receives Health Canada Approval for Trial
Positive
May 14, 2025

On May 14, 2025, AbCellera Biologics announced it received a No Objection Letter from Health Canada for its Clinical Trial Application for ABCL635, a novel antibody antagonist targeting the neurokinin 3 receptor for treating vasomotor symptoms associated with menopause. The Phase 1 clinical trial, expected to start in Q3 2025, will assess the safety and pharmacokinetics of ABCL635, marking a significant step in AbCellera’s efforts to offer a non-hormonal treatment for menopause-related hot flashes, potentially impacting the well-being of millions of women.

The most recent analyst rating on (ABCL) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

Spark’s Take on ABCL Stock

According to Spark, TipRanks’ AI Analyst, ABCL is a Neutral.

AbCellera Biologics faces significant financial and technical challenges, with declining revenues and weak technical indicators. Strategic advancements in drug development and a strong liquidity position offer some potential, but current valuation metrics are concerning. The recent patent appeal win provides a positive note, but substantial improvements are needed for a better outlook.

To see Spark’s full report on ABCL stock, click here.

Legal Proceedings
AbCellera Wins Patent Appeal Against Bruker
Positive
May 13, 2025

On May 12, 2025, AbCellera Biologics announced that the United States Court of Appeals for the Federal Circuit affirmed the validity of its U.S. Patent No. 10,087,408, which pertains to microfluidic devices used for culturing and selectively recovering cells. This decision follows a challenge by Bruker Cellular Analysis, Inc., which was rejected by the U.S. Patent Trial and Appeal Board and now confirmed by the Federal Circuit. This ruling strengthens AbCellera’s intellectual property portfolio and supports its ongoing patent infringement litigation against Bruker in the U.S. District Court for the Northern District of California.

The most recent analyst rating on (ABCL) stock is a Buy with a $14.00 price target. To see the full list of analyst forecasts on AbCellera Biologics stock, see the ABCL Stock Forecast page.

Spark’s Take on ABCL Stock

According to Spark, TipRanks’ AI Analyst, ABCL is a Neutral.

AbCellera Biologics exhibits a challenging financial and technical landscape, with declining revenues, profitability issues, and weak technical indicators. Although strategic drug development provides some future potential, current valuation metrics and financial performance are concerning, resulting in a low overall stock score.

To see Spark’s full report on ABCL stock, click here.

Product-Related AnnouncementsBusiness Operations and StrategyFinancial Disclosures
AbCellera Reports Q1 2025 Financial Results and New Antibody
Neutral
May 8, 2025

On May 8, 2025, AbCellera Biologics announced its financial results for the first quarter of 2025, reporting a total revenue of $4.2 million and a net loss of $45.6 million. The company highlighted the introduction of ABCL635, a potential first-in-class antibody for treating menopause-related vasomotor symptoms, with plans to start Phase 1 clinical trials in the latter half of 2025. Despite the financial loss, AbCellera maintained significant liquidity of over $800 million to support its strategic initiatives, including 97 partner-initiated programs and 16 molecules reaching the clinic.

Spark’s Take on ABCL Stock

According to Spark, TipRanks’ AI Analyst, ABCL is a Neutral.

AbCellera Biologics’ overall stock score is impacted by significant financial challenges, particularly in income and cash flow management, and negative valuation metrics. While technical indicators suggest some positive momentum, the company’s strategic transition to a clinical-stage biotech and strong liquidity offer potential, albeit with risks due to high R&D expenses and declining revenues.

To see Spark’s full report on ABCL stock, click here.

Business Operations and StrategyFinancial Disclosures
AbCellera Biologics Reports 2024 Financial Results and Growth
Neutral
Feb 27, 2025

AbCellera Biologics reported its financial results for the year 2024, highlighting significant progress in transitioning to a clinical-stage biotech company. The company maintained a strong cash position with over $800 million in liquidity and is set to initiate Phase 1 clinical trials for its first two programs in 2025. Despite a net loss of $162.9 million, AbCellera advanced three additional molecules into the clinic, bringing the total to 16, and started nine new partner-initiated programs, reflecting its continued growth and strategic investments.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.