ZimVie announces article on its Puros Cancellous Particulate Allograft

ZimVie announced the publication of an article titled Comparison of the Effects of Tissue Processing on the Physicochemical Properties of Bone Allografts in The International Journal of Oral & Maxillofacial Implants. ZimVie Dental’s Puros Cancellous Particulate Allograft bone substitute was shown to have a microstructure and preserved collagen matrix that suggests a higher ability to support bone formation than competitive freeze-dried allografts. The article looked at the impact of different tissue processing methods on the physicochemical properties of allografts, including Puros Cancellous Particulate Allograft, Creos, OraGraft, and MinerOss. The article highlights that the surface area of Puros Cancellous Particulate Allograft was 100 times higher than that of the freeze-dried allografts. A higher surface area as well as the strength and health of grafted sites are critical in implant dentistry, as an implant is only as strong as the bone that supports it. It further examined collagen fiber bundles and individual fibril arrangements on ZimVie’s Puros Cancellous Particulate Allograft compared to unprocessed human bone tissue. "The collagen microstructure of Puros Cancellous Particulate Allograft – and the size of individual fibers – was almost identical," states the research article. The surface area and microscopic texture of Puros Cancellous Particulate Allograft resulted in a significantly higher response from a specific type of stromal cells in vitro.