Opthea has completed enrollment of all patients in the COAST Phase 3 pivotal clinical trial investigating sozinibercept in combination with aflibercept, an anti-VEGF-A therapy, for the treatment of wet Age-related Macular Degeneration. The sozinibercept clinical program includes two Phase 3 pivotal trials, COAST and ShORe. Enrollment in ShORe is expected to be completed in calendar Q2 2024. Opthea intends to report topline results from these two trials by mid-2025.
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