Nyxoah announced data from a real-world case series evaluating treatment of three complete concentric collapse, or CCC, patients with the Genio hypoglossal nerve stimulation system. The investigator-sponsored case series was presented by Christian Plettenberg from the Universitatsklinikum Dusseldorf on December 8. Results showed an average apnea-hypopnea index, or AHI, decrease of 73% and Epworth Sleepiness Scale, or ESS, decrease of 58%. There were no implant related adverse events. The AHI in Patient 1 decreased from 44/h to 5.6/h, in Patient 2 from 24/h to 11.2/h and in Patient 3 from 36/h to 11.2/h. This resulted in an average reduction of 73%. The ESS in Patient 1 decreased from 15 to 2, in Patient 2 from 12 to 9 and in Patient 3 from 11 to 5. This resulted in an average reduction of 58%.
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