MiNK Therapeutics (INKT) announced the publication of a peer-reviewed article titled “CAR-iNKT Cells: Redefining the Frontiers of Cellular Immunotherapy” in Frontiers in Immunology. The publication, authored by leading experts in iNKT biology, underscores the power of iNKT cells as the next-generation off-the-shelf platform for treating solid tumors-where conventional cell therapies have failed to deliver lasting results. “This publication highlights what sets MiNK apart,” said Jennifer Buell, PhD, President and CEO of MiNK Therapeutics. “Our allogeneic iNKT platform, agenT-797, has already demonstrated potent, durable activity in solid tumors-without lymphodepletion, genetic modification, or complex conditioning. Building on that, we have shown that our CAR-iNKT cells deliver dual targeting through the invariant TCR and CAR, while actively reshaping the tumor microenvironment. With MiNK-215, our IL-15-armored, FAP-targeting CAR-iNKT therapy, we’re now tackling the stromal barriers that have long prevented immune infiltration in resistant tumors.”
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