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Merck announces results from Phase 3 CORALreef Lipids trial

Merck (MRK), known as MSD outside of the United States and Canada, announced the first presentation of results from the Phase 3 CORALreef Lipids trial demonstrating that treatment with enlicitide decanoate resulted in a statistically significant and clinically meaningful reduction in low-density lipoprotein cholesterol of 55.8% and of 59.7% in a post-hoc reanalysis compared to placebo at week 24. These late-breaking data will be presented for the first time today at the American Heart Association, AHA, Scientific Sessions 2025 and were selected for the Late-Breaking Science News Briefing.

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