Kazia Therapeutics announces the presentation of data highlighting promising clinical activity of EVT801 in high grade serous, HGS, Ovarian Cancer at the 15th Biennial Ovarian Cancer Research Symposium, co-presented by American Association of Cancer Research, AACR, and the Rivkin Center for Ovarian Cancer Research on Saturday, September 21, 2024 in Seattle Washington. Key points of the presentation included: A total of 26 patients were treated across 6 dosing cohorts ranging from 50mg once daily (QD) to 500mg twice daily; Patients with eleven different cancer types were enrolled in the study, with heavily pretreated advanced ovarian cancer being the most prevalent indication; Biomarkers have shown strong VEGFR3 expression in multiple indications, including ovarian cancer; Encouraging clinical activity in High Grade Serous ovarian cancer patients with forty-six percent having stable disease or for at least three cycles, including two patients who received 9 cycles; One patient had a partial response after 2 cycles of EVT801 therapy
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