Jaguar Health reports 2022 EPS ($36.18) vs. ($88.22) last year

Reports 2022 revenue $11.96M vs. $4.34M last year. "We are very pleased that growth in Mytesi revenue continued for the sixth quarter in a row in the fourth quarter of 2022," said Lisa Conte, Jaguar’s president and CEO. "As previously announced, the transition we completed throughout the end of 2021 and into the beginning of 2022 to a limited distribution network of specialty pharmacies resulted in a meaningful reduction in Mytesi distribution costs as well as a higher average net price. It is wonderful to see Mytesi continuing to grow following this transition and the successful implementation of our Mytesi patient access programs, including our ongoing disease state education and promotional activities. Most importantly, we are pleased with the realization of our mission of providing relief with a novel, plant-based, first-in-class mechanism of action to patients in need – including patients for whom no alternative therapeutic options exist. As I frequently state, what is really powerful about crofelemer is that it is a pipeline within a product. Our key near-term clinical activity is our Phase 3 pivotal OnTarget trial of our novel botanical drug, crofelemer, for our core follow-on indication of prophylaxis of cancer therapy-related diarrhea. Our efforts over the past year to expand the OnTarget trial to new U.S. and international sites – with trial sites now active in Eastern Europe – in both Georgia and the Republic of Serbia – as well as in Argentina and Taiwan – have significantly accelerated patient enrollment. As announced, enrollment reached approximately 75% one month ago. Enrollment is now at approximately 80%, and target trial enrollment of 256 patients is expected to complete in the second quarter of 2023, which is just around the corner," Conte said.