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Ionis Pharmaceuticals initiated with an Underperform at Bernstein

Bernstein analyst William Pickering initiated coverage of Ionis Pharmaceuticals with an Underperform rating and $31 price target. The company’s ASO technology appears to underperform RNAi on knockdown depth and/or dosing frequency, the analyst tells investors in a research note. The firm says Ionis has experienced "quite a few setbacks over the years," and that this trend will continue "until we have strong evidence to the contrary."

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