Hutchmed announced that Inmagene Biopharmaceuticals, a clinical stage biotechnology company developing differentiated therapies for immunological and inflammatory diseases, exercised the option to obtain an exclusive, worldwide and royalty-bearing license for IMG-007, a non-depleting humanized anti-OX40 mAb, and IMG-004, an oral non-covalent and reversible BTK inhibitor, with the right to sublicense through multiple tiers. The option was exercised pursuant to a collaboration between Inmagene and Hutchmed announced in 2021 to develop and commercialize a portfolio of drug candidates for I&I diseases. IMG-007 is being evaluated in Phase 2a studies in two indications: moderate-to-severe atopic dermatitis and alopecia areata. IMG-004 is being evaluated in a Phase 1 multiple ascending dose study.
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