Hutchmed (HCM) announced that Takeda (TAK) has submitted a new drug application, or NDA, to the Ministry of Health, Labour and Welfare, or MHLW, in Japan for the approval of fruquintinib for the treatment of adult patients with previously treated metastatic colorectal cancer, or CRC. Fruquintinib is a selective inhibitor of vascular endothelial growth factor receptors -1, -2 and -3, which play a pivotal role in blocking tumor angiogenesis. CRC has the highest incidence and second highest mortality rate among both men and women in Japan.
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