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Fulcrum Therapeutics downgraded to Underperform from Neutral at BofA
The Fly

Fulcrum Therapeutics downgraded to Underperform from Neutral at BofA

BofA analyst Tazeen Ahmad downgraded Fulcrum Therapeutics to Underperform from Neutral with a price target of $5, down from $8, after the FDA placed a full clinical hold on FTX-6058 for the treatment of sickle cell disease, or SCD. While awaiting additional color from the company, the firm considers it "prudent to take a more conservative stance" given the program is on full clinical. BofA lowered its odds of success for FTX-6058 to 10% from 20% and pushed out its launch assumption to 2026 from 2025.

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