Edgewise Therapeutics "announced the publication of the article, ‘Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy,’ in the Journal of Clinical Investigation." "This article illuminates the biology behind EDG-5506, demonstrating that modulation of fast skeletal muscle contraction protects against muscle injury, degeneration and fibrosis in models of DMD," said Alan Russell, Ph.D., Chief Scientific Officer of Edgewise and senior author of the article. "Importantly, even 15% inhibition provides maximum and robust protection of skeletal muscles and was associated with increases in strength and physical activity in mouse and dog models of DMD."
Published first on TheFly
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