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Acelyrin downgraded to Equal Weight from Overweight at Morgan Stanley
The Fly

Acelyrin downgraded to Equal Weight from Overweight at Morgan Stanley

Morgan Stanley downgraded Acelyrin to Equal Weight from Overweight with a price target of $19, down from $39, after the company announced that Part B of the Phase 2/3 study evaluating izokibep for hidradenitis suppurativa, or HS, did not meet the primary endpoint. A high discontinuation rate and strong placebo response contributed to a miss, notes the analyst, who moves to Equal Weight based on greater uncertainty on HS and what the firm calls a “challenging near-term set-up” for Acelyrin.

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