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Summit Therapeutics Announces Positive Phase III Trial Results

Story Highlights
  • Summit Therapeutics announced positive Phase III trial results for ivonescimab on May 30, 2025.
  • The trial showed significant improvement in progression-free survival, influencing potential FDA application timing.
  • Looking for the best stocks to buy? Follow the recommendations of top-performing analysts.
Summit Therapeutics Announces Positive Phase III Trial Results

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The latest update is out from Summit Therapeutics ( (SMMT) ).

On May 30, 2025, Summit Therapeutics announced positive topline results from its Phase III HARMONi clinical trial, which evaluated ivonescimab in combination with chemotherapy for patients with EGFR-mutated non-small cell lung cancer. The trial demonstrated a statistically significant improvement in progression-free survival and a positive trend in overall survival, suggesting potential benefits for patients in regions including North America and China. These results may influence Summit’s decision on the timing of a Biologics License Application filing with the FDA, as the agency requires a statistically significant overall survival benefit for marketing authorization.

The most recent analyst rating on (SMMT) stock is a Buy with a $31.00 price target. To see the full list of analyst forecasts on Summit Therapeutics stock, see the SMMT Stock Forecast page.

Spark’s Take on SMMT Stock

According to Spark, TipRanks’ AI Analyst, SMMT is a Neutral.

Summit Therapeutics’ stock score reflects significant financial challenges, including lack of revenue and ongoing losses, balanced by a strong equity position. Technical indicators show positive momentum, supporting short-term interest. Valuation remains weak due to negative earnings and no dividend. Positive clinical developments from the earnings call bolster the score, highlighting potential for future growth.

To see Spark’s full report on SMMT stock, click here.

More about Summit Therapeutics

Summit Therapeutics Inc. operates in the biotechnology industry, focusing on developing innovative therapies for unmet medical needs. The company is primarily engaged in the clinical development of ivonescimab, a novel bispecific antibody designed to treat non-small cell lung cancer (NSCLC) and other solid tumors.

Average Trading Volume: 3,939,205

Technical Sentiment Signal: Buy

Current Market Cap: $19.34B

Find detailed analytics on SMMT stock on TipRanks’ Stock Analysis page.

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