Pfizer Inc ((PFE)) announced an update on their ongoing clinical study.
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Pfizer Inc. is conducting a clinical study titled ‘A Phase 2b/3, Randomized, Double-Blind Study to Investigate the Efficacy, Safety, and Tolerability of Ponsegromab (PF-06946860) Compared With Placebo Both With Background First-Line Chemotherapy in Adult Participants With Cachexia and Metastatic Pancreatic Ductal Adenocarcinoma.’ The study aims to evaluate the effectiveness and safety of ponsegromab, a drug intended to treat cachexia and metastatic pancreatic cancer, conditions that often lead to significant weight loss and fatigue in patients.
The intervention being tested is ponsegromab, administered via subcutaneous injection every four weeks. Two dosages are being evaluated: 200 mg and 400 mg. The study also includes a placebo group for comparison.
This interventional study follows a randomized, parallel assignment model with quadruple masking, meaning participants, care providers, investigators, and outcomes assessors are blinded to the treatment allocations. The primary purpose is to assess treatment efficacy.
The study began on May 7, 2025, with an ongoing recruitment phase. The latest update was submitted on October 20, 2025. These dates are crucial as they indicate the study’s progress and timeline for potential results.
For investors, this study could significantly impact Pfizer’s market position, especially if ponsegromab proves effective. Success in this trial could enhance Pfizer’s portfolio in oncology treatments, potentially boosting stock performance and investor confidence. Competitors in the oncology space will be closely monitoring these developments.
The study is currently ongoing, with further details available on the ClinicalTrials portal.