Perspective Therapeutics, Inc. ((CATX)) announced an update on their ongoing clinical study.
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Perspective Therapeutics, Inc. (CATX) is conducting a clinical study titled A Phase I/IIa Image-Guided, Alpha-Particle Therapy Study of [203Pb]Pb-PSV359 and [212Pb]Pb-PSV359 in Patients With Solid Tumors That Are Known to be Fibroblast Activation Protein (FAP)-Positive. The study aims to evaluate the safety and efficacy of these drugs in treating FAP-positive solid tumors, which include several types of cancer such as pancreatic, gastric, and ovarian. This research is significant as it explores a novel approach to targeting cancer cells.
The study tests two drugs: [203Pb]Pb-PSV359, used for imaging, and [212Pb]Pb-PSV359, used for treatment. Both are administered intravenously, with the imaging drug helping to identify FAP-expressing cancers, and the treatment drug aiming to combat these tumors.
This interventional study is non-randomized and follows a sequential intervention model. It is unmasked, meaning both researchers and participants know the treatment being administered. The primary purpose is treatment-focused, aiming to establish a recommended phase 2 dose for the therapy.
The study began on November 25, 2024, with its primary completion and estimated overall completion dates yet to be announced. The latest update was submitted on October 14, 2025, indicating ongoing progress in the trial.
For investors, this study could have significant implications for CATX’s stock performance. Successful outcomes may boost investor confidence and position the company as a leader in innovative cancer treatments. However, the competitive landscape in oncology remains fierce, with numerous companies pursuing similar breakthroughs.
The study is currently recruiting, with further details available on the ClinicalTrials portal.